Assessing the impact of container marking implementation

Amgen is implementing new capabilities across the Amgen manufacturing network in order to code containers at the unit-level to reduce the possibility of mix-ups of unlabeled drug products. In order to prepare for the roll-out of these new capabilities, an assessment of the impact to throughput, packaging yield and eject rates was conducted. Discrete event simulation was utilized to assess the impact of implementing these new container marking capabilities on a vial inspection and packaging line at one of Amgen's key manufacturing sites. The impact assessment confirms that the new capabilities will have no impact to the throughput of the production line and minimal to no impact on packaging yield and eject rates. This assessment provides confidence that implementation can move forward without concerns of negative impacts to the production lines.

Department dc:contributor.department

Leaders for Global Operations Program at MIT

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2016

Author dc:creator

• Zielske, Iris Marie

Advisor dc:contributor.advisor

• Jarrod Goentzel and Y. Karen Zheng.

• Institute for Data, Systems, and Society.
• Sloan School of Management.
• Engineering Systems Division.
• Leaders for Global Operations Program.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/105629

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/105629