SAFETY AND EFFICACY OF INFLATABLE PENILE PROSTHESES IN PEOPLE WITH SPINAL CORD INJURY/DYSFUNCTION: A HOLISTIC TERTIARY REFERRAL CENTER WORKFLOW
type: CreativeWork
description: 1. Introduction ED is common after SCI/D and often coexists with NLUTD, NBD, spasticity, AD risk and high vulnerability to pressure injuries. PP implantation in SCI/D has historically been regarded as “high risk,” mainly because of increased infection, erosion/extrusion, revision and explant rates reported in older series. This study approaches IPP surgery in SCI/D as a workflow-dependent intervention, where outcomes are influenced by all steps in a Spinal Unit: pre-operative optimization, surgical technique and post-operative management. 2. Aim of the study The primary objective of the study was to assess the safety of contemporary IPP implantation in selected men with SCI/D managed within a structured multidisciplinary workflow by a tertiary referral Spinal Unit. Secondary objectives included: to assess functional efficacy of IPPs; to quantify patient satisfaction and likelihood of recommending the procedure; to evaluate impact on bladder and bowel management, and IC; to evaluate referral appropriateness in a large screened cohort and develop a referral appropriateness PP score (SCI/D-RAPPS) to use in routine clinical practice; to collect and summarize all the precautions adopted in a practical risk mitigation plan for other surgeons who are approaching IPP surgery in SCI/D. 3. Materials and methods After the approval by the Institutional Review Board, a prospective, longitudinal, single-center study was initiated in an Italian tertiary referral Spinal Unit setting. The initial enrollment period was from Feb 2023 to Jan 2024 with a 12-month-long follow-up period ending in Jan 2025. Due to reduced enrollment for strict selection process, the study was extended with a new enrollment period from Jun 2024 to May 2025, with follow-up period prolonged up to May 2026. Two linked samples were analyzed: (1) a consecutive cohort of 263 men with SCI/D evaluated for IPP during the enrollment period by our center, considered to develop the SCI/D-RAPPS; (2) the subgroup that un…
abstract: 1. Introduction ED is common after SCI/D and often coexists with NLUTD, NBD, spasticity, AD risk and high vulnerability to pressure injuries. PP implantation in SCI/D has historically been regarded as “high risk,” mainly because of increased infection, erosion/extrusion, revision and explant rates reported in older series. This study approaches IPP surgery in SCI/D as a workflow-dependent intervention, where outcomes are influenced by all steps in a Spinal Unit: pre-operative optimization, surgical technique and post-operative management. 2. Aim of the study The primary objective of the study was to assess the safety of contemporary IPP implantation in selected men with SCI/D managed within a structured multidisciplinary workflow by a tertiary referral Spinal Unit. Secondary objectives included: to assess functional efficacy of IPPs; to quantify patient satisfaction and likelihood of recommending the procedure; to evaluate impact on bladder and bowel management, and IC; to evaluate referral appropriateness in a large screened cohort and develop a referral appropriateness PP score (SCI/D-RAPPS) to use in routine clinical practice; to collect and summarize all the precautions adopted in a practical risk mitigation plan for other surgeons who are approaching IPP surgery in SCI/D. 3. Materials and methods After the approval by the Institutional Review Board, a prospective, longitudinal, single-center study was initiated in an Italian tertiary referral Spinal Unit setting. The initial enrollment period was from Feb 2023 to Jan 2024 with a 12-month-long follow-up period ending in Jan 2025. Due to reduced enrollment for strict selection process, the study was extended with a new enrollment period from Jun 2024 to May 2025, with follow-up period prolonged up to May 2026. Two linked samples were analyzed: (1) a consecutive cohort of 263 men with SCI/D evaluated for IPP during the enrollment period by our center, considered to develop the SCI/D-RAPPS; (2) the subgroup that un…
author: SAMPOGNA, GIANLUCA
language: eng
keywords: Settore MEDS-14/C - Urologia
date published: 2026-03-20
date modified: 2026-07-27T20:18:43Z
provider: Università degli Studi di Milano
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: Università degli Studi di Milano

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property ID: Handle
value: https://hdl.handle.net/2434/1227575