INVESTIGATION OF PLANT DERIVED NANOVESICLES FROM PLANT PRODUCTS AS NEW BIOACTIVE INGREDIENTS FOR FOOD SUPPLEMENTS AND FUNCIONAL FOODS DEVELOPMENT

Plant-derived nanovesicles represent an emerging research area that addresses critical challenges such as the stability, bioavailability, and efficacy of traditionally known plant extracts. This thesis explores plant-derived vesicles obtained from arugula leaves (ALVs) as a novel ingredient for the prevention of metabolic syndrome. Specifically, ALVs were obtained through the development of an innovative production method and their biological activites were investigated both in vitro and in vivo. The results of the in vivo study support the efficacy and safety of plant-derived nanovesicles, highlighting their potential as promising new ingredients for the development of functional foods and food supplements.

Grantor dc:publisher

Università degli Studi di Milano

Year dc:date

2025

Author dc:creator

• D'ADDUZIO, LORENZA

Contributors dc:contributor

• tutor: C. Lammi ; phd coordinator: G. Vistoli
• L. D'Adduzio
• LAMMI, CARMEN
• VISTOLI, GIULIO

• plant derived nanovesicle
• Caco-2 cell
• in vivo study
• metabolic syndrome
• Settore CHEM-07/B - Chimica degli alimenti

Statement dc:rights

• info:eu-repo/semantics/embargoedAccess

Language dc:language

eng

Handle dc:identifier

https://hdl.handle.net/2434/1163383

OAI identifier oai:identifier

oai:air.unimi.it:2434/1163383