Lower Limb Amputation in Patients with Vascular Disease
type: CreativeWork
description: The current prevalence of persons amputated at transmetatarsal level or higher in Sweden can be estimated to be between 5000 and 5500 persons (approx. 0.06 % of the population). The majority of these are patients with vascular disease (≈ 80%). In Sweden between 1000 and1100 new amputees can be expect every year. Less than 5% of all amputations will be related to causes other than vascular disease. Lower limb amputation (LEA) in patients with vascular disease may not only be highly disabling but also costly in hospital management. The incidence differs between countries due to age structure of the population, prevalence of vascular disease and the prevalence of diabetes. In Paper I we prospectively evaluated LLA performed at transmetatarsal level or higher during 10 years. The overall incidence of initial unilateral amputation in the diabetic population was eight times higher compared with that in the nondiabetic population (195 vs. 23 per 100,000 person-years). The incidence of contralateral amputation among diabetic amputees was 17 and among the nondiabetic amputees 13 per 100 amputee-years. The most frequent contralateral amputation level among the diabetic and nondiabetic patients was trans-tibial. The incidence of re-amputation among the diabetic amputees was 19 and among the nondiabetic amputees 14 per 100 amputee-years. The most frequent re-amputation level among diabetic patients was trans-tibial and among nondiabetic patients was trans-femoral. The 1-year mortality rate, adjusted for age and gender, did not differ significantly between the two groups. In Paper II we introduce a Swedish version of the Locomotor Capabilities Index (LCI) outcome instrument and evaluate its reliability and validity. Following the process of translation and cultural adaptation, the Swedish version of the LCI was found to be reliable and valid instrument that can provide a standardized measure of amputee-centered outcomes. In Paper III we tested two different dressings after trans…
abstract: The current prevalence of persons amputated at transmetatarsal level or higher in Sweden can be estimated to be between 5000 and 5500 persons (approx. 0.06 % of the population). The majority of these are patients with vascular disease (≈ 80%). In Sweden between 1000 and1100 new amputees can be expect every year. Less than 5% of all amputations will be related to causes other than vascular disease. Lower limb amputation (LEA) in patients with vascular disease may not only be highly disabling but also costly in hospital management. The incidence differs between countries due to age structure of the population, prevalence of vascular disease and the prevalence of diabetes. In Paper I we prospectively evaluated LLA performed at transmetatarsal level or higher during 10 years. The overall incidence of initial unilateral amputation in the diabetic population was eight times higher compared with that in the nondiabetic population (195 vs. 23 per 100,000 person-years). The incidence of contralateral amputation among diabetic amputees was 17 and among the nondiabetic amputees 13 per 100 amputee-years. The most frequent contralateral amputation level among the diabetic and nondiabetic patients was trans-tibial. The incidence of re-amputation among the diabetic amputees was 19 and among the nondiabetic amputees 14 per 100 amputee-years. The most frequent re-amputation level among diabetic patients was trans-tibial and among nondiabetic patients was trans-femoral. The 1-year mortality rate, adjusted for age and gender, did not differ significantly between the two groups. In Paper II we introduce a Swedish version of the Locomotor Capabilities Index (LCI) outcome instrument and evaluate its reliability and validity. Following the process of translation and cultural adaptation, the Swedish version of the LCI was found to be reliable and valid instrument that can provide a standardized measure of amputee-centered outcomes. In Paper III we tested two different dressings after trans…
author: Johannesson, Anton
language: eng
keywords: Orthopaedics, rehabilitation outcome, prosthetic, mortality, amputation, Incidence, limb
date published: 2009
date modified: 2026-07-24T03:00:02Z
provider: University of Lund
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: Department of Clinical Sciences, Lund University