Phytochemical and biological investigation of erigeron annus (L.) Pers for antimicrobial activity and potential DNA gyrase inhibitors
Compositae plants of the genus Erigeron have ca. 390 species, widely distributed in in most temperate regions around the world. Erigeron annus (L.) Pers. (fleabane) is one of the most valuable plants in the genus, used in Chinese folk medicine to treat indigestion, malaria, enteritis, hepatitis and hematuria increasingly since the 1970s. However it is not an indigenous species in China and has not been officially recorded in the Chinese Pharmacopeia. Very little research has been published on it biological activity and no activity against MRSA has been reported. In this research, whole plant material was collected in Shanghai, China and its chemical composition, antibacterial activity, DNA gyrase inhibitory activity and mutagenicity assessment were evaluated on isolated compounds and extracts.
Networked Digital Library of Theses and Dissertations