The Effects and Mechanisms of Phytochemicals on Alzheimer’s Disease Neuropathology

<p>Alzheimer’s disease effects millions of people, yet pharmacological treatments are limited. In the absence of effective treatments, identifying factors that can decrease the risk of developing Alzheimer’s disease is of significant interest. A growing body of epidemiological and experimental evidence suggests that dietary fruits and vegetables can have neuroprotective effects against the harmful effects of oxidative stress, neuroinflammation, and aging. These effects are mediated by various phytochemicals, which are compounds found in plants that can possess antioxidant, anti-inflammatory, and other beneficial properties. This review addresses epidemiological and experimental evidence for the effects and potential mechanisms of several commonly consumed phytochemicals on Alzheimer’s disease neuropathology and outcomes. The data suggest that regular consumption of bioactive phytochemicals from a variety of fruits and vegetables attenuates age- and insult-related Alzheimer’s disease neuropathology.</p>

Name thesis:degree_name

Doctor of Psychology (PsyD)

Level thesis:degree_level

Doctoral Project

Discipline thesis:degree_discipline

Psychology

Year

2021

Author dc:creator

• Ross, David

Contributors dc:contributor

• Richard E. Hartman
• Grace J. Lee

• Psychology
• Alzheimer Disease--drug therapy
• Phytochemicals--Therapeutic use.

Statement dc:rights

• This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Language dc:language

English

Repository record dc:identifier

https://scholarsrepository.llu.edu/etd/1168

OAI identifier oai:identifier

oai:scholarsrepository.llu.edu:etd-2688