Patterns of Fetal Lamb Regional Cerebral Blood Flow during and after Prolonged Hypoxia
type: CreativeWork
description: [Abstract not included] Speculation: In the fetal lamb during prolonged intrauterine hypoxia, total and regional cerebral blood flows increase to the same extent without evidence of preferential shunting to critical brainstem or subcortical areas. Neuropathologic studies have indicated relative sparing of these areas during similar animal experimental or human neonatal conditions. This suggests that the pattern of hypoxic ischemic insult to the neonatal central nervous system associated with asphyxia may differ from that produced by hypoxia alone. In addition, during asphyxia these pathologic changes may result primarily from hypotension and decreased regional cerebral blood flow, or from regional metabolic derangements in the cerebral tissue.
abstract: [Abstract not included] Speculation: In the fetal lamb during prolonged intrauterine hypoxia, total and regional cerebral blood flows increase to the same extent without evidence of preferential shunting to critical brainstem or subcortical areas. Neuropathologic studies have indicated relative sparing of these areas during similar animal experimental or human neonatal conditions. This suggests that the pattern of hypoxic ischemic insult to the neonatal central nervous system associated with asphyxia may differ from that produced by hypoxia alone. In addition, during asphyxia these pathologic changes may result primarily from hypotension and decreased regional cerebral blood flow, or from regional metabolic derangements in the cerebral tissue.
author: Ashwal, Stephen
author: Majcher, John S.
author: Vain, Nestor
author: Longo, Lawrence D.
language: English
keywords: Circulatory and Respiratory Physiology, Neuroscience and Neurobiology, Physiology, Cerebral Anoxia.
date published: 1979-12-01T08:00:00Z
date modified: 2026-07-24T02:54:10Z
provider: Loma Linda University
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: Loma Linda University