[Abstract not included]
Speculation: In the fetal lamb during prolonged intrauterine hypoxia, total and regional cerebral blood flows increase to the same extent without evidence of preferential shunting to critical brainstem or subcortical areas. Neuropathologic studies have indicated relative sparing of these areas during similar animal experimental or human neonatal conditions. This suggests that the pattern of hypoxic ischemic insult to the neonatal central nervous system associated with asphyxia may differ from that produced by hypoxia alone. In addition, during asphyxia these pathologic changes may result primarily from hypotension and decreased regional cerebral blood flow, or from regional metabolic derangements in the cerebral tissue.
","abstract_html":"<p>[Abstract not included]</p> <p>Speculation: In the fetal lamb during prolonged intrauterine hypoxia, total and regional cerebral blood flows increase to the same extent without evidence of preferential shunting to critical brainstem or subcortical areas. Neuropathologic studies have indicated relative sparing of these areas during similar animal experimental or human neonatal conditions. This suggests that the pattern of hypoxic ischemic insult to the neonatal central nervous system associated with asphyxia may differ from that produced by hypoxia alone. In addition, during asphyxia these pathologic changes may result primarily from hypotension and decreased regional cerebral blood flow, or from regional metabolic derangements in the cerebral tissue.</p>","abstract_has_math":false,"creators":["Ashwal, Stephen","Majcher, John S.","Vain, Nestor","Longo, Lawrence D."],"institution":null,"degree_name":"Master of Science (MS)","degree_level":"Thesis","degree_discipline":"Physiology","degree_department":null,"school":null,"contributors":["Lawrence D. Longo","Raymond D. Gilbert","Donald D. Rafuse"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1979,"date_issued":"1979-12-01T08:00:00Z","date_published":"1979-12-01T08:00:00Z","updated_at":"2026-07-24T02:54:10Z","subjects":["Circulatory and Respiratory Physiology","Neuroscience and Neurobiology","Physiology","Cerebral Anoxia."],"languages":["English"],"rights":["This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://scholarsrepository.llu.edu/etd/1751","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Lawrence D. Longo","Raymond D. Gilbert","Donald D. Rafuse"]},{"key":"dc:creator","label":"Author","values":["Ashwal, Stephen","Majcher, John S.","Vain, Nestor","Longo, Lawrence D."]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"thesis:degree_discipline","label":"Discipline","values":["Physiology"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science (MS)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Circulatory and Respiratory Physiology","Neuroscience and Neurobiology","Physiology","Cerebral Anoxia."]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["English"]},{"key":"dc:rights","label":"Dc Rights","values":["This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://scholarsrepository.llu.edu/etd/1751"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["[Abstract not included]
Speculation: In the fetal lamb during prolonged intrauterine hypoxia, total and regional cerebral blood flows increase to the same extent without evidence of preferential shunting to critical brainstem or subcortical areas. Neuropathologic studies have indicated relative sparing of these areas during similar animal experimental or human neonatal conditions. This suggests that the pattern of hypoxic ischemic insult to the neonatal central nervous system associated with asphyxia may differ from that produced by hypoxia alone. In addition, during asphyxia these pathologic changes may result primarily from hypotension and decreased regional cerebral blood flow, or from regional metabolic derangements in the cerebral tissue.
"]},{"key":"dc:title","label":"Title","values":["Patterns of Fetal Lamb Regional Cerebral Blood Flow during and after Prolonged Hypoxia"]}]}],"canonical_facts":{"dc:contributor":["Lawrence D. Longo","Raymond D. Gilbert","Donald D. Rafuse"],"dc:creator":["Ashwal, Stephen","Majcher, John S.","Vain, Nestor","Longo, Lawrence D."],"dc:description.abstract":["[Abstract not included]
Speculation: In the fetal lamb during prolonged intrauterine hypoxia, total and regional cerebral blood flows increase to the same extent without evidence of preferential shunting to critical brainstem or subcortical areas. Neuropathologic studies have indicated relative sparing of these areas during similar animal experimental or human neonatal conditions. This suggests that the pattern of hypoxic ischemic insult to the neonatal central nervous system associated with asphyxia may differ from that produced by hypoxia alone. In addition, during asphyxia these pathologic changes may result primarily from hypotension and decreased regional cerebral blood flow, or from regional metabolic derangements in the cerebral tissue.
"],"dc:identifier":["https://scholarsrepository.llu.edu/etd/1751"],"dc:language":["English"],"dc:rights":["This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights."],"dc:subject":["Circulatory and Respiratory Physiology","Neuroscience and Neurobiology","Physiology","Cerebral Anoxia."],"dc:title":["Patterns of Fetal Lamb Regional Cerebral Blood Flow during and after Prolonged Hypoxia"],"thesis:degree_discipline":["Physiology"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["Master of Science (MS)"]},"updated_at":"2026-07-24T02:54:10Z"}