In concurrent infections of Trichinella spiralis and Trypanosoma equiperdum, the survival times vary in the early stages of the Trichinella infection. On Days 1 and 4, the mean survival times are significantly increased, and on Days 3 and 7 they are markedly decreased. This decrease is probably due to intestinal tissue invasion. Mice infected with trypanosomes after the 7th day of the Trichinella infection have survival time increases to a significant point and a steady leveling off to Day 21. It is suggested that the antibodies produced against the Trichinella worms slow down multiplication of trypanosomes and increase the survival time in the mice. It is proposed that a protective effect is produced in the mixed infection of T. spiralis and T. equiperdum.
","abstract_html":"<p>In concurrent infections of <em>Trichinella spiralis</em> and <em>Trypanosoma equiperdum</em>, the survival times vary in the early stages of the <em>Trichinella</em> infection. On Days 1 and 4, the mean survival times are significantly increased, and on Days 3 and 7 they are markedly decreased. This decrease is probably due to intestinal tissue invasion. Mice infected with trypanosomes after the 7th day of the <em>Trichinella</em> infection have survival time increases to a significant point and a steady leveling off to Day 21. It is suggested that the antibodies produced against the <em>Trichinella</em> worms slow down multiplication of trypanosomes and increase the survival time in the mice. It is proposed that a protective effect is produced in the mixed infection of <em>T. spiralis</em> and <em>T. equiperdum</em>.</p>","abstract_has_math":false,"creators":["Nembhard, Pauline A."],"institution":null,"degree_name":"Master of Science (MS)","degree_level":"Thesis","degree_discipline":"Microbiology","degree_department":null,"school":null,"contributors":["Edward D. Wagner","Raymond E. Ryckman","Yuk Lin Ho","Robert F. Wood"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1974,"date_issued":"1974-08-01T07:00:00Z","date_published":"1974-08-01T07:00:00Z","updated_at":"2026-07-24T02:54:10Z","subjects":["Animal Experimentation and Research","Microbiology","Parasitology","Trypanosoma; Trichinella"],"languages":["English"],"rights":["This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://scholarsrepository.llu.edu/etd/1691","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Edward D. Wagner","Raymond E. Ryckman","Yuk Lin Ho","Robert F. Wood"]},{"key":"dc:creator","label":"Author","values":["Nembhard, Pauline A."]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"thesis:degree_discipline","label":"Discipline","values":["Microbiology"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science (MS)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Animal Experimentation and Research","Microbiology","Parasitology","Trypanosoma; Trichinella"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["English"]},{"key":"dc:rights","label":"Dc Rights","values":["This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://scholarsrepository.llu.edu/etd/1691"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["In concurrent infections of Trichinella spiralis and Trypanosoma equiperdum, the survival times vary in the early stages of the Trichinella infection. On Days 1 and 4, the mean survival times are significantly increased, and on Days 3 and 7 they are markedly decreased. This decrease is probably due to intestinal tissue invasion. Mice infected with trypanosomes after the 7th day of the Trichinella infection have survival time increases to a significant point and a steady leveling off to Day 21. It is suggested that the antibodies produced against the Trichinella worms slow down multiplication of trypanosomes and increase the survival time in the mice. It is proposed that a protective effect is produced in the mixed infection of T. spiralis and T. equiperdum.
"]},{"key":"dc:title","label":"Title","values":["Concurrent Infections of TRYPANOSOMA EQUIPERDUM and TRICHINELLA SPIRALIS in Mice"]}]}],"canonical_facts":{"dc:contributor":["Edward D. Wagner","Raymond E. Ryckman","Yuk Lin Ho","Robert F. Wood"],"dc:creator":["Nembhard, Pauline A."],"dc:description.abstract":["In concurrent infections of Trichinella spiralis and Trypanosoma equiperdum, the survival times vary in the early stages of the Trichinella infection. On Days 1 and 4, the mean survival times are significantly increased, and on Days 3 and 7 they are markedly decreased. This decrease is probably due to intestinal tissue invasion. Mice infected with trypanosomes after the 7th day of the Trichinella infection have survival time increases to a significant point and a steady leveling off to Day 21. It is suggested that the antibodies produced against the Trichinella worms slow down multiplication of trypanosomes and increase the survival time in the mice. It is proposed that a protective effect is produced in the mixed infection of T. spiralis and T. equiperdum.
"],"dc:identifier":["https://scholarsrepository.llu.edu/etd/1691"],"dc:language":["English"],"dc:rights":["This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights."],"dc:subject":["Animal Experimentation and Research","Microbiology","Parasitology","Trypanosoma; Trichinella"],"dc:title":["Concurrent Infections of TRYPANOSOMA EQUIPERDUM and TRICHINELLA SPIRALIS in Mice"],"thesis:degree_discipline":["Microbiology"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["Master of Science (MS)"]},"updated_at":"2026-07-24T02:54:10Z"}