The Effect of Glucose on Neutrophilic Phagocytosis

<p>Samples of blood were obtained from thirty healthy young adult males (Loma Linda University School of Dentistry), and contaminated with bacteria. Varying concentrations of pure glucose were added to this mixture to observe the effect of the glucose on in vitro neutrophilic phagocytosis. As the glucose levels increased a statistically significant suppression was noted in the ability of the neutrophilic leukocytes to engulf Staphylococcus epidermidis.</p> <p>It was not possible, however, to predict the degree of suppression for any particular level of glucose added nor is it possible to state that suppression will occur in any one individual.</p> <p>Two methods of phagocytic index determinations were used. The first recorded the percentage of neutrophils that had phagocytized and the second counted the number of bacteria per phagocyte. Statistically no difference was noted between the two methods.</p>

Name thesis:degree_name

Master of Science (MS)

Level thesis:degree_level

Thesis

Discipline thesis:degree_discipline

Periodontics

Year

1967

Author dc:creator

• Adams, Donald F.

Contributors dc:contributor

• Edwin M. Collins
• Charles T. Smith
• Ralph R. Steinman
• Richard C. Oliver
• Alvin V. Schiess

• Bacteriology
• Periodontics and Periodontology
• Glucose; Phagocytosis

Statement dc:rights

• This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.

Language dc:language

English

Repository record dc:identifier

https://scholarsrepository.llu.edu/etd/1415

OAI identifier oai:identifier

oai:scholarsrepository.llu.edu:etd-2187