The Effect of a PUFA Diet on Human Red Blood Cell Levels of 2, 3-DPG
Fasting blood was collected at weekly intervals and the level of 2,3-DPG of the red blood cell was determined in 15 male subjects age 28 to 57 with serum cholesterol levels greater than 250 mg%. A lactovegetarian diet containing no cholesterol, a high level of dietary fiber and a P/S ratio of 4.0 was provided for 28 days. During the course of the experimental period the 2,3-DPG increased by an average of 0.83> «moles/ml red blood cell which was highly significant (p^.001). This significant increase of 2,3-DPG which relates to an increased oxygen delivery capability of the red blood cells would indicate the benefit of this type of diet to the individual with a high risk of heart disease.
Biochemical Phenomena, Metabolism, and Nutrition, Dietetics and Clinical Nutrition, Cholesterol, Dietary; Blood Cell Count
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