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Loma Linda University

Artificial Respiration during the Apnea of Cerebral Trauma

Abstract

dc:description.abstract

<p>Cerebral concussion often results in profound respiratory depression. The earlier workers in the field of experimental concussion concluded that artificial respiration could be a life preserving procedure in 4 many instances. More recently, however, it has been held that this form of resuscitation is of little or no value.</p> <p>Because of this conflict in viewpoint and inasmuch as the latter interpretation was made as a result of studies that were not primarily directed towards assessing the worth of artificial respiration during the apnea of experimentally induced concussion, this study was planned with the hope of resolving the differences of opinion.</p> <p>A series of experiments was performed in which concussion, together with prolonged apnea, was induced in anesthetized c^ts by a spring 1 loaded hammer while recording arterial blood pressure and respiration. When it appeared that the demise of the animal was imminent because of a rapidly falling arterial pressure, artificial respiration was provided in order to study the beneficial effects, if any, on the blood pressure and respiration.</p> <p>In 6 instances out of 27 preparations, adequate spontaneous respiration returned. The arterial blood pressure was maintained at levels of 90 ram Hg. or higher for variable periods of ti e up to 12 hours after which the animals were electively sacrificed. Four preparations expired while being ventilated; in the balance demise accompanied the discontinuance of artificial respiration.</p> <p>It is concluded that artificial respiration may be of value in the apnea of concussion in certain instances. In a majority of cases, however. j it appears that when the blow is strong enough to cause profound 1 respiratory depression, survival of the animal may not be anticipated.</p>

Degree

thesis:*
Name thesis:degree_name
Master of Science (MS)
Level thesis:degree_level
Thesis
Discipline thesis:degree_discipline
Physiology
Year
1958

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Christiansen, Thorvald W.
Contributors dc:contributor
  • J. Earl Thomas
  • Kenneth E. Kellogg
  • Raymond A. Mortensen
  • Jack D. Zwemer
  • Vernon C. Bohr
  • Melvin I Haley

Subjects

dc:subject × 2

Rights

dc:rights
Statement dc:rights
  • This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights.
Language dc:language
English

Identifiers

dc:identifier.*
Repository record dc:identifier
https://scholarsrepository.llu.edu/etd/617
OAI identifier oai:identifier
oai:scholarsrepository.llu.edu:etd-1704

Chain of custody

source
Harvested from
Loma Linda University
Base URL
scholarsrepository.llu.edu/do/oai/
Last updated
2026-07-24
Source record
OAI-PMH GetRecord
citation

Christiansen, Thorvald W.. Artificial Respiration during the Apnea of Cerebral Trauma. Thesis thesis, 1958. https://scholarsrepository.llu.edu/etd/617