Nine male marathon runners were exercised to exhaustion to determine the effects of a 27-hour fast on endurance performance. Each subject completed two exercise tests at 72% peak oxygen uptake (Vo2max), one following a 27-hour fast and one three hours after a pre-exercise meal, in random order. Fasting caused a 44.7±5.8% (±SE) decrease in endurance performance (p2(9.3±2.0%), heart rate (8.4±2.4%), rating of perceived exertion (RPE), and psychological fatigue, evident within the first 60 minutes of exercise. There was no difference in plasma glucose or epinephrine levels. Muscle glycogen degraded at the same rate (0.48±.15 vs 0.47±.28 u moles • g -1.min-1 in the non-fasted and fasted tests, respectively) despite lower respiratory exchange ratio (R) and elevated free fatty acid (FFA) levels. Lactate, insulin,. norepinephrine (NE), and 3,4-dihydroxyphenylacetic acid (dopac) were all increased in the fasted test (p
","abstract_html":"<p>Nine male marathon runners were exercised to exhaustion to determine the effects of a 27-hour fast on endurance performance. Each subject completed two exercise tests at 72% peak oxygen uptake (Vo<sub>2</sub>max), one following a 27-hour fast and one three hours after a pre-exercise meal, in random order. Fasting caused a 44.7±5.8% (±SE) decrease in endurance performance (p2(9.3±2.0%), heart rate (8.4±2.4%), rating of perceived exertion (RPE), and psychological fatigue, evident within the first 60 minutes of exercise. There was no difference in plasma glucose or epinephrine levels. Muscle glycogen degraded at the same rate (0.48±.15 vs 0.47±.28 u moles • g <sup><sub>-1.min-1 </sub></sup>in the non-fasted and fasted tests, respectively) despite lower respiratory exchange ratio (R) and elevated free fatty acid (FFA) levels. Lactate, insulin,. norepinephrine (NE), and 3,4-dihydroxyphenylacetic acid (dopac) were all increased in the fasted test (p</p>","abstract_has_math":false,"creators":["Carlson, Kristin A."],"institution":null,"degree_name":"Master of Science (MS)","degree_level":"Thesis","degree_discipline":"Nutrition","degree_department":null,"school":null,"contributors":["David C. Nieman","U.D. Regisler","James W. Blankenship","Kristian Lindsted","Murray E. Brandstater"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1986,"date_issued":"1986-12-01T08:00:00Z","date_published":"1986-12-01T08:00:00Z","updated_at":"2026-07-24T02:52:59Z","subjects":["Exercise Physiology","Nutrition","Running; Fasting"],"languages":["English"],"rights":["This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://scholarsrepository.llu.edu/etd/624","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["David C. Nieman","U.D. Regisler","James W. Blankenship","Kristian Lindsted","Murray E. Brandstater"]},{"key":"dc:creator","label":"Author","values":["Carlson, Kristin A."]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"thesis:degree_discipline","label":"Discipline","values":["Nutrition"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science (MS)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Exercise Physiology","Nutrition","Running; Fasting"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["English"]},{"key":"dc:rights","label":"Dc Rights","values":["This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://scholarsrepository.llu.edu/etd/624"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Nine male marathon runners were exercised to exhaustion to determine the effects of a 27-hour fast on endurance performance. Each subject completed two exercise tests at 72% peak oxygen uptake (Vo2max), one following a 27-hour fast and one three hours after a pre-exercise meal, in random order. Fasting caused a 44.7±5.8% (±SE) decrease in endurance performance (p2(9.3±2.0%), heart rate (8.4±2.4%), rating of perceived exertion (RPE), and psychological fatigue, evident within the first 60 minutes of exercise. There was no difference in plasma glucose or epinephrine levels. Muscle glycogen degraded at the same rate (0.48±.15 vs 0.47±.28 u moles • g -1.min-1 in the non-fasted and fasted tests, respectively) despite lower respiratory exchange ratio (R) and elevated free fatty acid (FFA) levels. Lactate, insulin,. norepinephrine (NE), and 3,4-dihydroxyphenylacetic acid (dopac) were all increased in the fasted test (p
"]},{"key":"dc:title","label":"Title","values":["Running Endurance in 27-hour Fasted Humans"]}]}],"canonical_facts":{"dc:contributor":["David C. Nieman","U.D. Regisler","James W. Blankenship","Kristian Lindsted","Murray E. Brandstater"],"dc:creator":["Carlson, Kristin A."],"dc:description.abstract":["Nine male marathon runners were exercised to exhaustion to determine the effects of a 27-hour fast on endurance performance. Each subject completed two exercise tests at 72% peak oxygen uptake (Vo2max), one following a 27-hour fast and one three hours after a pre-exercise meal, in random order. Fasting caused a 44.7±5.8% (±SE) decrease in endurance performance (p2(9.3±2.0%), heart rate (8.4±2.4%), rating of perceived exertion (RPE), and psychological fatigue, evident within the first 60 minutes of exercise. There was no difference in plasma glucose or epinephrine levels. Muscle glycogen degraded at the same rate (0.48±.15 vs 0.47±.28 u moles • g -1.min-1 in the non-fasted and fasted tests, respectively) despite lower respiratory exchange ratio (R) and elevated free fatty acid (FFA) levels. Lactate, insulin,. norepinephrine (NE), and 3,4-dihydroxyphenylacetic acid (dopac) were all increased in the fasted test (p
"],"dc:identifier":["https://scholarsrepository.llu.edu/etd/624"],"dc:language":["English"],"dc:rights":["This title appears here courtesy of the author, who has granted Loma Linda University a limited, non-exclusive right to make this publication available to the public. The author retains all other copyrights."],"dc:subject":["Exercise Physiology","Nutrition","Running; Fasting"],"dc:title":["Running Endurance in 27-hour Fasted Humans"],"thesis:degree_discipline":["Nutrition"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["Master of Science (MS)"]},"updated_at":"2026-07-24T02:52:59Z"}