Sleep-wake Cycle Assessment in Type 2 Diabetes and Salivary Melatonin Correlates
type: CreativeWork
description: p=.047). Additionally, there were significant inverse relationships between melatonin collected at two hours before bed time and latency (Ï=-.87; p=.001), wake after sleep onset (Ï =-.69; p=.02) and nocturnal activity (Ï =-.67; p=.03). Latency was inversely correlated with melatonin collected at bed time (Ï =-.69; p=.02). These findings suggest that T2DM presents disturbances in the homeostatic and circadian drives, mainly characterized by less consistency across days of the daily circadian signal, higher rhythm fragmentation and lower rhythm amplitude. In addition to the lower melatonin levels, the decrease in the amplitude of the activity rhythm may also be involved in circadian alterations of the sleep-wake cycle.
abstract: p=.047). Additionally, there were significant inverse relationships between melatonin collected at two hours before bed time and latency (Ï=-.87; p=.001), wake after sleep onset (Ï =-.69; p=.02) and nocturnal activity (Ï =-.67; p=.03). Latency was inversely correlated with melatonin collected at bed time (Ï =-.69; p=.02). These findings suggest that T2DM presents disturbances in the homeostatic and circadian drives, mainly characterized by less consistency across days of the daily circadian signal, higher rhythm fragmentation and lower rhythm amplitude. In addition to the lower melatonin levels, the decrease in the amplitude of the activity rhythm may also be involved in circadian alterations of the sleep-wake cycle.
author: Cavalcanti, Paula Regina Aguiar
language: English
keywords: Physical Therapy, Diabetes Mellitus, Type 2; Circadian Rhythm; Sleep physiology; Melantonin - physiology;, Sleep-wake cycle, Salivary melatonin, circadian rhythms, Homeostatic rhythms, Rhythm fragmentation
date published: 2013-06-01T07:00:00Z
date modified: 2026-07-24T02:52:15Z
provider: Loma Linda University
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: Loma Linda University