{"id":{"repo_id":"lethbridge","oai_identifier":"oai:opus.uleth.ca:10133/6342"},"canonical_url":"https://search.dev.ndltd.org/etd/lethbridge/oai:opus.uleth.ca:10133/6342","repository":{"repo_id":"lethbridge","name":"University of Lethbridge","base_url":"https://opus.uleth.ca/server/oai/request"},"display":{"title":"Impact of aerobic exercise training on body weight, energy intake, and appetite-regulating hormones in rats","abstract":"Post-exercise energy compensation (EC) through increased energy intake (EI) leads to lower than anticipated weight reduction. This study sought to determine the mechanisms, independent of bodyweight (BW), that are involved in EC over an 8-week period of voluntary wheel running. Twelve-week-old male Sprague Dawley rats (n=30) fed an AIN-93M diet were randomized into 3 groups: 1) sedentary control (SED); 2) voluntary wheel exercise (EX); and 3) sedentary, weight-matched to aerobic exercise (SED-WM) for 8 weeks. Measures of BW, adiposity, appetite-regulating hormones, gut microbiota, and NA/VTA volume were assessed. BW was initially reduced in EX, but no differences were present between SED and EX at the end of the study. EI in EX steadily increased over the course of the study. Fat mass, leptin, and insulin were reduced in EX. Exercise-induced improvements in body composition may contribute to reductions in tonic hormones and satiety, potentially contributing to an increase in EI.","abstract_html":"Post-exercise energy compensation (EC) through increased energy intake (EI) leads to lower than anticipated weight reduction. This study sought to determine the mechanisms, independent of bodyweight (BW), that are involved in EC over an 8-week period of voluntary wheel running. Twelve-week-old male Sprague Dawley rats (n=30) fed an AIN-93M diet were randomized into 3 groups: 1) sedentary control (SED); 2) voluntary wheel exercise (EX); and 3) sedentary, weight-matched to aerobic exercise (SED-WM) for 8 weeks. Measures of BW, adiposity, appetite-regulating hormones, gut microbiota, and NA/VTA volume were assessed. BW was initially reduced in EX, but no differences were present between SED and EX at the end of the study. EI in EX steadily increased over the course of the study. Fat mass, leptin, and insulin were reduced in EX. Exercise-induced improvements in body composition may contribute to reductions in tonic hormones and satiety, potentially contributing to an increase in EI.","abstract_has_math":false,"creators":["Durocher, Isabelle","University of Lethbridge. Faculty of Arts and Science"],"institution":null,"degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2022,"date_issued":"2022","date_published":"2022","updated_at":"2026-07-27T20:02:20Z","subjects":["Energy compensation","Nutrition","Exercise","Hedonic appetite-regulatory system","Homeostatic appetite-regulatory system","Gut microbiota","Body Weight Regulation"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["hdl:10133/6342"],"render_values":[{"text":"hdl:10133/6342","href":null,"code":true}]}]},"links":{"outbound_url":null,"outbound_label":null,"outbound_source":null},"metadata_groups":[{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.issued","label":"Date","values":["2022"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Energy compensation","Nutrition","Exercise","Hedonic appetite-regulatory system","Homeostatic appetite-regulatory system","Gut microbiota","Body Weight Regulation"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["hdl:10133/6342"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.other","label":"Dc Description Other","values":["Post-exercise energy compensation (EC) through increased energy intake (EI) leads to lower than anticipated weight reduction. This study sought to determine the mechanisms, independent of bodyweight (BW), that are involved in EC over an 8-week period of voluntary wheel running. Twelve-week-old male Sprague Dawley rats (n=30) fed an AIN-93M diet were randomized into 3 groups: 1) sedentary control (SED); 2) voluntary wheel exercise (EX); and 3) sedentary, weight-matched to aerobic exercise (SED-WM) for 8 weeks. Measures of BW, adiposity, appetite-regulating hormones, gut microbiota, and NA/VTA volume were assessed. BW was initially reduced in EX, but no differences were present between SED and EX at the end of the study. EI in EX steadily increased over the course of the study. Fat mass, leptin, and insulin were reduced in EX. Exercise-induced improvements in body composition may contribute to reductions in tonic hormones and satiety, potentially contributing to an increase in EI."]},{"key":"dc:title","label":"Title","values":["Impact of aerobic exercise training on body weight, energy intake, and appetite-regulating hormones in rats"]}]}],"canonical_facts":{"dc:date.issued":["2022"],"dc:description.other":["Post-exercise energy compensation (EC) through increased energy intake (EI) leads to lower than anticipated weight reduction. This study sought to determine the mechanisms, independent of bodyweight (BW), that are involved in EC over an 8-week period of voluntary wheel running. Twelve-week-old male Sprague Dawley rats (n=30) fed an AIN-93M diet were randomized into 3 groups: 1) sedentary control (SED); 2) voluntary wheel exercise (EX); and 3) sedentary, weight-matched to aerobic exercise (SED-WM) for 8 weeks. Measures of BW, adiposity, appetite-regulating hormones, gut microbiota, and NA/VTA volume were assessed. BW was initially reduced in EX, but no differences were present between SED and EX at the end of the study. EI in EX steadily increased over the course of the study. Fat mass, leptin, and insulin were reduced in EX. Exercise-induced improvements in body composition may contribute to reductions in tonic hormones and satiety, potentially contributing to an increase in EI."],"dc:identifier":["hdl:10133/6342"],"dc:subject":["Energy compensation","Nutrition","Exercise","Hedonic appetite-regulatory system","Homeostatic appetite-regulatory system","Gut microbiota","Body Weight Regulation"],"dc:title":["Impact of aerobic exercise training on body weight, energy intake, and appetite-regulating hormones in rats"],"dc:type":["Thesis"]},"updated_at":"2026-07-27T20:02:20Z"}