Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, c2009
Escherichia coli O157:H7 lineage persistence and colonization of cattle in vitro
Abstract
dc:description.abstractEscherichia coli O157:H7 is an important human pathogen that resides primarily in cattle and feedlot environments. E. coli O157:H7 can be divided into phylogenetic groups termed lineages; lineage I strains are responsible for most human illnesses. An understanding of the etiology of these lineages within cattle and the feedlot environment could allow for more effective surveillance and mitigation strategies. There were no lineage associated differences in growth or survival of E. coli O157:H7 in bovine feces at 4°C, 12°C or 25°C. Lineage I strains more readily colonized cattle jejunum tissue and a bovine colonic cell line than lineage II and intermediate type strains. Enhanced colonization of cattle by lineage I strains may increase the persistence of these strains in feedlots via re-infection and increased shedding. This outcome could increase the transmission of lineage I strains to the food supply and increase the potential for these strains to cause human illness.
Degree
thesis:*- Grantor dc:publisher
- Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, c2009
- Year dc:date.issued
- 2009
Author and committee
dc:creator, dc:contributor.*- Authors dc:creator
-
- Lowe, Ross M.S.
- University of Lethbridge. Faculty of Arts and Science
- Advisors dc:contributor.supervisor
-
- Sharma, Ranjana
- Selinger, L. Brent
Subjects
dc:subject × 4Rights
- Language dc:language.iso
- en_US
Identifiers
dc:identifier.*- Identifier
- hdl:10133/2509