{"id":{"repo_id":"ku","oai_identifier":"oai:kuscholarworks.ku.edu:1808/36619"},"canonical_url":"https://search.dev.ndltd.org/etd/ku/oai:kuscholarworks.ku.edu:1808/36619","repository":{"repo_id":"ku","name":"University of Kansas","base_url":"https://kuscholarworks.ku.edu/server/oai/request"},"display":{"title":"Decarboxylative Transformations Facilitated via Intermolecular Halogen Transposition using gem-Bromonitroalkanes","abstract":"Carboxylic acids offer a sustainable alternative to fossil-fuel derived feedstocks. These shelf-stable and highly abundant substrates can be sourced from renewable biological sources in the form of amino acids, fatty acids, and sugar acids. In addition to being readily available, their facile activation via decarboxylation delivers value-added chemicals in a cost effective and eco-friendly manner. In this context, photoredox-catalyzed elimination and cross-coupling methodologies were developed via merger of decarboxylation with intermolecular halogen transposition using gem-bromonitroalkanes. A systematic investigation of this novel synthetic framework enabled mild, green, and efficient conversion of carboxylic acids into electron-deficient styrenes, enamides, and β-nitroamines.","abstract_html":"Carboxylic acids offer a sustainable alternative to fossil-fuel derived feedstocks. These shelf-stable and highly abundant substrates can be sourced from renewable biological sources in the form of amino acids, fatty acids, and sugar acids. In addition to being readily available, their facile activation via decarboxylation delivers value-added chemicals in a cost effective and eco-friendly manner. In this context, photoredox-catalyzed elimination and cross-coupling methodologies were developed via merger of decarboxylation with intermolecular halogen transposition using gem-bromonitroalkanes. A systematic investigation of this novel synthetic framework enabled mild, green, and efficient conversion of carboxylic acids into electron-deficient styrenes, enamides, and β-nitroamines.","abstract_has_math":false,"creators":["Brar, Deshkanwar Singh"],"institution":"University of Kansas","degree_name":"Ph.D.","degree_level":null,"degree_discipline":"Chemistry","degree_department":null,"school":null,"contributors":[],"advisors":["Tunge, Jon A."],"committee_chairs":[],"committee_members":[],"year":2026,"date_issued":"2026-05-31","date_published":"2026-05-31","updated_at":"2026-07-24T02:45:54Z","subjects":["Decarboxylation","Free-Radicals","Halogen-Atom Transfer","Photoredox Catalysis"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["https://www.proquest.com/LegacyDocView/DISSNUM/32404907"],"render_values":[{"text":"https://www.proquest.com/LegacyDocView/DISSNUM/32404907","href":"https://www.proquest.com/LegacyDocView/DISSNUM/32404907","code":true}]}]},"links":{"outbound_url":"https://hdl.handle.net/1808/36619","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Tunge, Jon A."]},{"key":"dc:creator","label":"Author","values":["Brar, Deshkanwar Singh"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2026-04-08T19:38:44Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2026-04-08T19:38:44Z"]},{"key":"dc:date.issued","label":"Date","values":["2026-05-31"]},{"key":"dc:publisher","label":"Institution","values":["University of Kansas"]},{"key":"dc:type","label":"Dc Type","values":["Dissertation"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Chemistry"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Decarboxylation","Free-Radicals","Halogen-Atom Transfer","Photoredox Catalysis"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.other","label":"Dc Identifier Other","values":["https://www.proquest.com/LegacyDocView/DISSNUM/32404907"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://hdl.handle.net/1808/36619"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Carboxylic acids offer a sustainable alternative to fossil-fuel derived feedstocks. These shelf-stable and highly abundant substrates can be sourced from renewable biological sources in the form of amino acids, fatty acids, and sugar acids. In addition to being readily available, their facile activation via decarboxylation delivers value-added chemicals in a cost effective and eco-friendly manner. In this context, photoredox-catalyzed elimination and cross-coupling methodologies were developed via merger of decarboxylation with intermolecular halogen transposition using gem-bromonitroalkanes. A systematic investigation of this novel synthetic framework enabled mild, green, and efficient conversion of carboxylic acids into electron-deficient styrenes, enamides, and β-nitroamines."]},{"key":"dc:title","label":"Title","values":["Decarboxylative Transformations Facilitated via Intermolecular Halogen Transposition using gem-Bromonitroalkanes"]}]}],"canonical_facts":{"dc:contributor.advisor":["Tunge, Jon A."],"dc:creator":["Brar, Deshkanwar Singh"],"dc:date.accessioned":["2026-04-08T19:38:44Z"],"dc:date.available":["2026-04-08T19:38:44Z"],"dc:date.issued":["2026-05-31"],"dc:description.abstract":["Carboxylic acids offer a sustainable alternative to fossil-fuel derived feedstocks. These shelf-stable and highly abundant substrates can be sourced from renewable biological sources in the form of amino acids, fatty acids, and sugar acids. In addition to being readily available, their facile activation via decarboxylation delivers value-added chemicals in a cost effective and eco-friendly manner. In this context, photoredox-catalyzed elimination and cross-coupling methodologies were developed via merger of decarboxylation with intermolecular halogen transposition using gem-bromonitroalkanes. A systematic investigation of this novel synthetic framework enabled mild, green, and efficient conversion of carboxylic acids into electron-deficient styrenes, enamides, and β-nitroamines."],"dc:identifier.other":["https://www.proquest.com/LegacyDocView/DISSNUM/32404907"],"dc:identifier.uri":["https://hdl.handle.net/1808/36619"],"dc:language.iso":["en"],"dc:publisher":["University of Kansas"],"dc:subject":["Decarboxylation","Free-Radicals","Halogen-Atom Transfer","Photoredox Catalysis"],"dc:title":["Decarboxylative Transformations Facilitated via Intermolecular Halogen Transposition using gem-Bromonitroalkanes"],"dc:type":["Dissertation"],"thesis:degree_discipline":["Chemistry"],"thesis:degree_name":["Ph.D."]},"updated_at":"2026-07-24T02:45:54Z"}