{"id":{"repo_id":"iastate","oai_identifier":"oai:dr.lib.iastate.edu:20.500.12876/30918"},"canonical_url":"https://search.dev.ndltd.org/etd/iastate/oai:dr.lib.iastate.edu:20.500.12876/30918","repository":{"repo_id":"iastate","name":"Iowa State University","base_url":"https://dr.lib.iastate.edu/server/oai/request"},"display":{"title":"A stochastic simulation approach for improving response in genomic selection","abstract":"<p>The world population is increasing rapidly and is projected to hit 9.1 billion by 2050.</p> <p>As the demand for food increases, agriculture production will continue to play a signiﬁcant</p> <p>role. As a method to maintain and increase agriculture production, plant breeding is critical.</p> <p>To improve eﬃciency in the plant breeding process, an interdisciplinary eﬀort is needed.</p> <p>Operations research as a discipline focuses on decision making and eﬃcient and eﬀective</p> <p>strategy design. In this thesis, operations research tools of simulation, optimization and</p> <p>mathematical modeling are applied to plant breeding, speciﬁcally Genomic Selection (GS).</p> <p>GS techniques allow breeders to select the best plants to make crosses by predicting, for</p> <p>example, the heights of the plants using the genotypic data at an early stage of the plant</p> <p>growth cycle, saving both time and cost that would otherwise be necessary to grow the</p> <p>plants to maturity before their heights can be measured. A major limitation of existing GS</p> <p>approaches is the trade-oﬀ between short-term genetic gains and long-term growth potential.</p> <p>Some approaches focus on achieving short-term genetic gains at the cost of losing genetic</p> <p>diversity for long-term gains, and others aim to maximize the long-term genetic gains but</p> <p>are unable to achieve it by the breeding deadline. Our contribution is to deﬁne a new look</p> <p>ahead method for assessing a selection decision, which evaluates the probability to achieve</p> <p>both genetic diversity and breeding deadline. Moreover, we propose a heuristic algorithm</p> <p>to ﬁnd an optimal selection decision with respect to the new method. Our new selection</p> <p>method outperforms the other selection methods in the literature.</p>","abstract_html":"&lt;p&gt;The world population is increasing rapidly and is projected to hit 9.1 billion by 2050.&lt;/p&gt; &lt;p&gt;As the demand for food increases, agriculture production will continue to play a signiﬁcant&lt;/p&gt; &lt;p&gt;role. As a method to maintain and increase agriculture production, plant breeding is critical.&lt;/p&gt; &lt;p&gt;To improve eﬃciency in the plant breeding process, an interdisciplinary eﬀort is needed.&lt;/p&gt; &lt;p&gt;Operations research as a discipline focuses on decision making and eﬃcient and eﬀective&lt;/p&gt; &lt;p&gt;strategy design. In this thesis, operations research tools of simulation, optimization and&lt;/p&gt; &lt;p&gt;mathematical modeling are applied to plant breeding, speciﬁcally Genomic Selection (GS).&lt;/p&gt; &lt;p&gt;GS techniques allow breeders to select the best plants to make crosses by predicting, for&lt;/p&gt; &lt;p&gt;example, the heights of the plants using the genotypic data at an early stage of the plant&lt;/p&gt; &lt;p&gt;growth cycle, saving both time and cost that would otherwise be necessary to grow the&lt;/p&gt; &lt;p&gt;plants to maturity before their heights can be measured. A major limitation of existing GS&lt;/p&gt; &lt;p&gt;approaches is the trade-oﬀ between short-term genetic gains and long-term growth potential.&lt;/p&gt; &lt;p&gt;Some approaches focus on achieving short-term genetic gains at the cost of losing genetic&lt;/p&gt; &lt;p&gt;diversity for long-term gains, and others aim to maximize the long-term genetic gains but&lt;/p&gt; &lt;p&gt;are unable to achieve it by the breeding deadline. Our contribution is to deﬁne a new look&lt;/p&gt; &lt;p&gt;ahead method for assessing a selection decision, which evaluates the probability to achieve&lt;/p&gt; &lt;p&gt;both genetic diversity and breeding deadline. Moreover, we propose a heuristic algorithm&lt;/p&gt; &lt;p&gt;to ﬁnd an optimal selection decision with respect to the new method. Our new selection&lt;/p&gt; &lt;p&gt;method outperforms the other selection methods in the literature.&lt;/p&gt;","abstract_has_math":false,"creators":["Moeinizade, Saba"],"institution":null,"degree_name":"Master of Science","degree_level":"thesis","degree_discipline":"Industrial and Manufacturing Systems Engineering","degree_department":"Department of Industrial and Manufacturing Systems Engineering","school":null,"contributors":[],"advisors":["Guiping Hu"],"committee_chairs":[],"committee_members":[],"year":2018,"date_issued":"2018-01-01","date_published":"2018-01-01","updated_at":"2026-07-24T02:39:41Z","subjects":[],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["archive/lib.dr.iastate.edu/etd/16735/"],"render_values":[{"text":"archive/lib.dr.iastate.edu/etd/16735/","href":null,"code":true}]}]},"links":{"outbound_url":"https://dr.lib.iastate.edu/handle/20.500.12876/30918","outbound_label":"Repository record","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Guiping Hu"]},{"key":"dc:contributor.department","label":"Department","values":["Department of Industrial and Manufacturing Systems Engineering"]},{"key":"dc:creator","label":"Author","values":["Moeinizade, Saba"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2019-01-15T09:15:34.000"]},{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2020-06-30T03:13:14Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2020-06-30T03:13:14Z"]},{"key":"dc:date.issued","label":"Date","values":["2018-01-01"]},{"key":"dc:type","label":"Dc Type","values":["thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Industrial and Manufacturing Systems Engineering"]},{"key":"thesis:degree_level","label":"Degree Level","values":["thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["archive/lib.dr.iastate.edu/etd/16735/"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://dr.lib.iastate.edu/handle/20.500.12876/30918"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["<p>The world population is increasing rapidly and is projected to hit 9.1 billion by 2050.</p> <p>As the demand for food increases, agriculture production will continue to play a signiﬁcant</p> <p>role. As a method to maintain and increase agriculture production, plant breeding is critical.</p> <p>To improve eﬃciency in the plant breeding process, an interdisciplinary eﬀort is needed.</p> <p>Operations research as a discipline focuses on decision making and eﬃcient and eﬀective</p> <p>strategy design. In this thesis, operations research tools of simulation, optimization and</p> <p>mathematical modeling are applied to plant breeding, speciﬁcally Genomic Selection (GS).</p> <p>GS techniques allow breeders to select the best plants to make crosses by predicting, for</p> <p>example, the heights of the plants using the genotypic data at an early stage of the plant</p> <p>growth cycle, saving both time and cost that would otherwise be necessary to grow the</p> <p>plants to maturity before their heights can be measured. A major limitation of existing GS</p> <p>approaches is the trade-oﬀ between short-term genetic gains and long-term growth potential.</p> <p>Some approaches focus on achieving short-term genetic gains at the cost of losing genetic</p> <p>diversity for long-term gains, and others aim to maximize the long-term genetic gains but</p> <p>are unable to achieve it by the breeding deadline. Our contribution is to deﬁne a new look</p> <p>ahead method for assessing a selection decision, which evaluates the probability to achieve</p> <p>both genetic diversity and breeding deadline. Moreover, we propose a heuristic algorithm</p> <p>to ﬁnd an optimal selection decision with respect to the new method. Our new selection</p> <p>method outperforms the other selection methods in the literature.</p>"]},{"key":"dc:format.mimetype","label":"Dc Format Mimetype","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["A stochastic simulation approach for improving response in genomic selection"]}]}],"canonical_facts":{"dc:contributor.advisor":["Guiping Hu"],"dc:contributor.department":["Department of Industrial and Manufacturing Systems Engineering"],"dc:creator":["Moeinizade, Saba"],"dc:date":["2019-01-15T09:15:34.000"],"dc:date.accessioned":["2020-06-30T03:13:14Z"],"dc:date.available":["2020-06-30T03:13:14Z"],"dc:date.issued":["2018-01-01"],"dc:description.abstract":["<p>The world population is increasing rapidly and is projected to hit 9.1 billion by 2050.</p> <p>As the demand for food increases, agriculture production will continue to play a signiﬁcant</p> <p>role. As a method to maintain and increase agriculture production, plant breeding is critical.</p> <p>To improve eﬃciency in the plant breeding process, an interdisciplinary eﬀort is needed.</p> <p>Operations research as a discipline focuses on decision making and eﬃcient and eﬀective</p> <p>strategy design. In this thesis, operations research tools of simulation, optimization and</p> <p>mathematical modeling are applied to plant breeding, speciﬁcally Genomic Selection (GS).</p> <p>GS techniques allow breeders to select the best plants to make crosses by predicting, for</p> <p>example, the heights of the plants using the genotypic data at an early stage of the plant</p> <p>growth cycle, saving both time and cost that would otherwise be necessary to grow the</p> <p>plants to maturity before their heights can be measured. A major limitation of existing GS</p> <p>approaches is the trade-oﬀ between short-term genetic gains and long-term growth potential.</p> <p>Some approaches focus on achieving short-term genetic gains at the cost of losing genetic</p> <p>diversity for long-term gains, and others aim to maximize the long-term genetic gains but</p> <p>are unable to achieve it by the breeding deadline. Our contribution is to deﬁne a new look</p> <p>ahead method for assessing a selection decision, which evaluates the probability to achieve</p> <p>both genetic diversity and breeding deadline. Moreover, we propose a heuristic algorithm</p> <p>to ﬁnd an optimal selection decision with respect to the new method. Our new selection</p> <p>method outperforms the other selection methods in the literature.</p>"],"dc:format.mimetype":["application/pdf"],"dc:identifier":["archive/lib.dr.iastate.edu/etd/16735/"],"dc:identifier.uri":["https://dr.lib.iastate.edu/handle/20.500.12876/30918"],"dc:language.iso":["en"],"dc:title":["A stochastic simulation approach for improving response in genomic selection"],"dc:type":["thesis"],"thesis:degree_discipline":["Industrial and Manufacturing Systems Engineering"],"thesis:degree_level":["thesis"],"thesis:degree_name":["Master of Science"]},"updated_at":"2026-07-24T02:39:41Z"}