{"id":{"repo_id":"greece","oai_identifier":"oai:10442/1755"},"canonical_url":"https://search.dev.ndltd.org/etd/greece/oai:10442/1755","repository":{"repo_id":"greece","name":"Greek National Archive of PhD Theses","base_url":"https://phdtheses.ekt.gr/eadd_oai/request"},"display":{"title":"ΓΟΝΙΔΙΑΚΗ ΕΚΦΡΑΣΗ ΔΙΕΓΕΡΜΕΝΩΝ ΑΝΘΡΩΠΙΝΩΝ Τ-ΛΕΜΦΟΚΥΤΤΑΡΩΝ: ΡΥΘΜΙΣΗ ΤΗΣ ΕΚΦΡΑΣΗΣ ΤΟΥ ΓΟΝΙΔΙΟΥ 2 ΚΑΤΑ ΤΗ ΔΙΑΡΚΕΙΑ ΤΟΥ ΚΥΤΤΑΡΙΚΟΥ ΚΥΚΛΟΥ","abstract":"THE OBJECT OF THIS STUDY WAS TO RESEARCH INTO THE CELL CYCLE AND REGULATION OF THE CD2 GLUE EXPRESSION IN PHA STIMULATED HUMAN PERIPHERAL BLOOD T-LYMPHOCYTES.THE ACCURATE POSITION OF STIMULATED LYMPHOCYTES IN THE CELL CYCLE WAS DETERMINED BY USING THE \"PREMATURE CHROMOSOME CONDENSATION\" METHOD (PCC), WHICH OFFERS THE POSSIBILITY OF STUDYING THE DISTRIBUTION OF LYMPHOCYTES IN G1, S AND G2 PHASES. THE RESULTS OF THIS STUDY SUPPORT THE ASPECT THAT THE CD2 GENE EXPRESSION SEEMS TO BE CONTROLLED BY A COMBINATION OF REGULATORY MECHANISMS WHICH ARE ACTIVE AT TRANSCRIPTIONAL, POST TRANSCRIPTIONAL AND POST TRANSLATIONAL LEVEL. THE POSSIBILITY OF REGULATORY MECHANISMS AT OTHER LEVELS TOO, CANNOT BE EXCLUDED. THE CD2 GENE IS ONE OF A LARGE GROUP OF PHA INDUCIBLE GENES. THE FLUCTUATION OF CD2-MRNA THROUGH THE CELL CYCLE SUGGESTS THAT CD2 GENE IS PROBABLY EXPRESSED IN A CELL CYCLE DEPENDENT MANNER (MAINLY THROUGH G1 PHASE). FURTHERMORE THE INCREASED EXPRESSION OF THE CD2 GENE (MULTILAYER ROSE BE USED AS A MARKER OF CELL CYCLE PROGRESSION IN THE TRANSITION OF T-LYMPHOCYTES FROM GO TO S PHASE.","abstract_html":"THE OBJECT OF THIS STUDY WAS TO RESEARCH INTO THE CELL CYCLE AND REGULATION OF THE CD2 GLUE EXPRESSION IN PHA STIMULATED HUMAN PERIPHERAL BLOOD T-LYMPHOCYTES.THE ACCURATE POSITION OF STIMULATED LYMPHOCYTES IN THE CELL CYCLE WAS DETERMINED BY USING THE "PREMATURE CHROMOSOME CONDENSATION" METHOD (PCC), WHICH OFFERS THE POSSIBILITY OF STUDYING THE DISTRIBUTION OF LYMPHOCYTES IN G1, S AND G2 PHASES. THE RESULTS OF THIS STUDY SUPPORT THE ASPECT THAT THE CD2 GENE EXPRESSION SEEMS TO BE CONTROLLED BY A COMBINATION OF REGULATORY MECHANISMS WHICH ARE ACTIVE AT TRANSCRIPTIONAL, POST TRANSCRIPTIONAL AND POST TRANSLATIONAL LEVEL. THE POSSIBILITY OF REGULATORY MECHANISMS AT OTHER LEVELS TOO, CANNOT BE EXCLUDED. THE CD2 GENE IS ONE OF A LARGE GROUP OF PHA INDUCIBLE GENES. THE FLUCTUATION OF CD2-MRNA THROUGH THE CELL CYCLE SUGGESTS THAT CD2 GENE IS PROBABLY EXPRESSED IN A CELL CYCLE DEPENDENT MANNER (MAINLY THROUGH G1 PHASE). FURTHERMORE THE INCREASED EXPRESSION OF THE CD2 GENE (MULTILAYER ROSE BE USED AS A MARKER OF CELL CYCLE PROGRESSION IN THE TRANSITION OF T-LYMPHOCYTES FROM GO TO S PHASE.","abstract_has_math":false,"creators":["Kitsiou, Paraskevi","Κίτσιου, Παρασκευή"],"institution":"National and Kapodistrian University of Athens","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1991,"date_issued":"1991","date_published":"1991","updated_at":"2026-07-24T02:25:05Z","subjects":["CD2 ΓΟΝΙΔΙΟ","CD2 ΚΥΤΤΑΡΟΕΠΙΦΑΝΕΙΑΚΟ ΑΝΤΙΓΟΝΟ","ΑΝΘΡΩΠΙΝΑ Τ-ΛΕΜΦΟΚΥΤΤΑΡΑ","Γονιδιακή έκφραση","Γονιδιακή ρύθμιση","Ε-ΡΟΔΑΚΑΣ","Κυτταρικός κύκλος","ΠΡΟΩΡΗ ΧΡΩΜΟΣΩΜΑΤΙΚΗ ΣΥΜΠΥΚΝΩΣΗ","Φυτοαιμαγλουτινίνη (PHA)","CD2 CELL SURFACE ANTIGEN","CD2 GENE","Cell cycle","E-ROSETTE","Gene expression","Gene regulation","Human T-lympocytes","Phytohemagglutinin (PHA)","Premature chromosome condensation","Φυσικές Επιστήμες","Βιολογία","Natural Sciences","Biological Sciences"],"languages":["gre"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["10.12681/eadd/1755"],"render_values":[{"text":"10.12681/eadd/1755","href":"https://doi.org/10.12681/eadd/1755","code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/10442/hedi/1755","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Kitsiou, Paraskevi","Κίτσιου, Παρασκευή"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["1991"]},{"key":"dc:publisher","label":"Institution","values":["National and Kapodistrian University of Athens","Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)"]},{"key":"dc:type","label":"Dc Type","values":["PhD Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["CD2 ΓΟΝΙΔΙΟ","CD2 ΚΥΤΤΑΡΟΕΠΙΦΑΝΕΙΑΚΟ ΑΝΤΙΓΟΝΟ","ΑΝΘΡΩΠΙΝΑ Τ-ΛΕΜΦΟΚΥΤΤΑΡΑ","Γονιδιακή έκφραση","Γονιδιακή ρύθμιση","Ε-ΡΟΔΑΚΑΣ","Κυτταρικός κύκλος","ΠΡΟΩΡΗ ΧΡΩΜΟΣΩΜΑΤΙΚΗ ΣΥΜΠΥΚΝΩΣΗ","Φυτοαιμαγλουτινίνη (PHA)","CD2 CELL SURFACE ANTIGEN","CD2 GENE","Cell cycle","E-ROSETTE","Gene expression","Gene regulation","Human T-lympocytes","Phytohemagglutinin (PHA)","Premature chromosome condensation","Φυσικές Επιστήμες","Βιολογία","Natural Sciences","Biological Sciences"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["gre"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["10.12681/eadd/1755","http://hdl.handle.net/10442/hedi/1755"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["THE OBJECT OF THIS STUDY WAS TO RESEARCH INTO THE CELL CYCLE AND REGULATION OF THE CD2 GLUE EXPRESSION IN PHA STIMULATED HUMAN PERIPHERAL BLOOD T-LYMPHOCYTES.THE ACCURATE POSITION OF STIMULATED LYMPHOCYTES IN THE CELL CYCLE WAS DETERMINED BY USING THE \"PREMATURE CHROMOSOME CONDENSATION\" METHOD (PCC), WHICH OFFERS THE POSSIBILITY OF STUDYING THE DISTRIBUTION OF LYMPHOCYTES IN G1, S AND G2 PHASES. THE RESULTS OF THIS STUDY SUPPORT THE ASPECT THAT THE CD2 GENE EXPRESSION SEEMS TO BE CONTROLLED BY A COMBINATION OF REGULATORY MECHANISMS WHICH ARE ACTIVE AT TRANSCRIPTIONAL, POST TRANSCRIPTIONAL AND POST TRANSLATIONAL LEVEL. THE POSSIBILITY OF REGULATORY MECHANISMS AT OTHER LEVELS TOO, CANNOT BE EXCLUDED. THE CD2 GENE IS ONE OF A LARGE GROUP OF PHA INDUCIBLE GENES. THE FLUCTUATION OF CD2-MRNA THROUGH THE CELL CYCLE SUGGESTS THAT CD2 GENE IS PROBABLY EXPRESSED IN A CELL CYCLE DEPENDENT MANNER (MAINLY THROUGH G1 PHASE). FURTHERMORE THE INCREASED EXPRESSION OF THE CD2 GENE (MULTILAYER ROSE BE USED AS A MARKER OF CELL CYCLE PROGRESSION IN THE TRANSITION OF T-LYMPHOCYTES FROM GO TO S PHASE.","ΣΚΟΠΟΣ ΑΥΤΗΣ ΤΗΣ ΕΡΓΑΣΙΑΣ ΗΤΑΝ Η ΜΕΛΕΤΗ ΤΟΥ ΚΥΤΤΑΡΙΚΟΥ ΚΥΚΛΟΥ ΚΑΙ ΤΗΣ ΡΥΘΜΙΣΗΣ ΤΗΣ ΕΚΦΡΑΣΗΣ ΤΟΥ CD2 ΓΟΝΙΔΙΟΥ ΣΕ ΔΙΕΓΕΡΜΕΝΑ ΜΕ PHA ΑΝΘΡΩΠΙΝΑ Τ-ΛΕΜΦΟΚΥΤΤΑΡΑ ΤΟΥΠΕΡΙΦΕΡΙΚΟΥ ΑΙΜΑΤΟΣ. Η ΑΚΡΙΒΗΣ ΘΕΣΗ ΤΟΥ ΔΙΕΓΕΡΜΕΝΟΥ ΛΕΜΦΟΚΥΤΤΑΡΟΥ ΜΕΣΑ ΣΤΟΝ ΚΥΤΤΑΡΙΚΟ ΚΥΚΛΟ ΠΡΟΣΔΙΟΡΙΣΤΗΚΕ ΜΕ ΤΗ ΜΕΘΟΔΟ ΤΗΣ \"ΠΡΟΩΡΗΣ ΧΡΩΜΟΣΩΜΑΤΙΚΗΣ ΣΥΜΠΥΚΝΩΣΗΣ\" Η ΟΠΟΙΑ ΔΙΝΕΙ ΤΗΝ ΔΥΝΑΤΟΤΗΤΑ ΝΑ ΜΕΛΕΤΗΘΕΙ Η ΚΑΤΑΝΟΜΗ ΤΩΝ ΛΕΜΦΟΚΥΤΤΑΡΩΝ ΣΤΙΣΥΠΟΦΑΣΕΙΣ ΤΗΣ G1 ΚΑΙ ΣΤΙΣ ΦΑΣΕΙΣ S KAI G2. ΤΑ ΑΠΟΤΕΛΕΣΜΑΤΑ ΑΥΤΗΣ ΤΗΣ ΜΕΛΕΤΗΣ ΥΠΟΣΤΗΡΙΖΟΥΝ ΤΗΝ ΑΠΟΨΗ ΟΤΙ Η ΕΚΦΡΑΣΗ ΤΟΥ CD2 ΓΟΝΙΔΙΟΥ ΦΑΙΝΕΤΑΙ ΝΑ ΕΛΕΓΧΕΤΑΙ ΑΠΟ ΕΝΑ ΣΥΝΔΙΑΣΜΟ ΡΥΘΜΙΣΤΙΚΩΝ ΜΗΧΑΝΙΣΜΩΝ ΠΟΥ ΔΡΟΥΝ ΣΕ ΜΕΤΑΓΡΑΦΙΚΗ, ΜΕΤΑ-ΜΕΤΑΓΡΑΦΙΚΟΚΑΙ ΜΕΤΑ-ΜΕΤΑΦΡΑΣΤΙΚΟ ΕΠΙΠΕΔΟ ΧΩΡΙΣ Ν'ΑΠΟΚΛΕΙΟΝΤΑΙ ΕΛΕΓΧΟΙ ΚΑΙ ΣΕ ΑΛΛΑ ΕΠΙΠΕΔΑ. ΤΟ CD2 ΓΟΝΙΔΙΟ ΑΝΗΚΕΙ ΣΤΗΝ ΟΜΑΔΑ ΓΟΝΙΔΙΩΝ ΤΩΝ Τ- ΛΕΜΦΟΚΥΤΤΑΡΩΝ ΠΟΥ ΕΝΕΡΓΟΠΟΙΟΥΝΤΑΙ ΚΑΤΟΠΙΝ ΔΙΕΓΕΡΣΗΣ ΤΟΥ ΚΥΤΤΑΡΟΥ ΜΕ ΡΗΑ. Η ΔΙΑΚΥΜΑΝΣΗ ΤΗΣ ΣΥΣΣΩΡΕΥΣΗΣ ΤΟΥ CD2-MRNA ΚΑΤΑ ΤΗ ΔΙΑΡΚΕΙΑ ΤΟΥ ΚΥΤΤΑΡΙΚΟΥ ΚΥΚΛΟΥ ΔΕΙΧΝΕΙ ΟΤΙ Η ΕΚΦΡΑΣΗ ΤΟΥ ΓΟΝΙΔΙΟΥ ΠΙΘΑΝΟΝ ΝΑ ΕΛΕΓΧΕΤΑΙ ΑΠΟ ΤΟΝ ΚΥΤΤΑΡΙΚΟ ΚΥΚΛΟ. ΕΠΙΠΛΕΟΝ Η ΑΥΞΗΜΕΝΗ ΕΚΦΡΑΣΗ ΤΟΥ ΓΟΝΙΔΙΟΥ CD2 (ΟΠΩΣ ΑΥΤΗ ΕΛΕΓΧΕΤΑΙ ΑΠΟ ΤΗΝ ΑΥΞΗΜΕΝΗ ΙΚΑΝΟΤΗΤΑ ΤΩΝ ΛΕΜΦΟΚΥΤΤΑΡΩΝ ΝΑ ΣΧΗΜΑΤΙΖΟΥΝ ΠΟΛΥΣΤΡΩΜΑΤΙΚΕΣ ΡΟΖΕΤΤΕΣ), ΜΠΟΡΕΙ ΝΑ ΧΡΗΣΙΜΟΠΟΙΗΘΕΙ ΣΑΝ ΔΕΙΚΤΗΣ ΕΛΕΓΧΟΥ ΤΗΣ ΠΡΟΟΔΟΥ ΤΟΥ ΛΕΜΦΟΚΥΤΤΑΡΟΥ ΜΕΣΑ ΣΤΟ ΚΥΤΤΑΡΙΚΟ ΚΥΚΛΟ ΚΑΙ ΚΥΡΙΩΣ ΝΑ ΔΙΑΠΙΣΤΩΘΕΙ Η ΜΕΤΑΒΑΣΗ ΤΟΥ ΚΥΤΤΑΡΟΥ ΑΠΟ ΤΗ ΦΑΣΗ ΗΡΕΜΙΑΣ (GO) ΣΤΗ ΦΑΣΗ ΣΥΝΘΕΣΗΣ (S)."]},{"key":"dc:title","label":"Title","values":["ΓΟΝΙΔΙΑΚΗ ΕΚΦΡΑΣΗ ΔΙΕΓΕΡΜΕΝΩΝ ΑΝΘΡΩΠΙΝΩΝ Τ-ΛΕΜΦΟΚΥΤΤΑΡΩΝ: ΡΥΘΜΙΣΗ ΤΗΣ ΕΚΦΡΑΣΗΣ ΤΟΥ ΓΟΝΙΔΙΟΥ 2 ΚΑΤΑ ΤΗ ΔΙΑΡΚΕΙΑ ΤΟΥ ΚΥΤΤΑΡΙΚΟΥ ΚΥΚΛΟΥ","GENE EXPRESSION IN STIMULATED HUMAN T-LYMPHOCYTES: REGULATION OF THE CD2 GENE EXPRESSION"]}]}],"canonical_facts":{"dc:creator":["Kitsiou, Paraskevi","Κίτσιου, Παρασκευή"],"dc:date":["1991"],"dc:description":["THE OBJECT OF THIS STUDY WAS TO RESEARCH INTO THE CELL CYCLE AND REGULATION OF THE CD2 GLUE EXPRESSION IN PHA STIMULATED HUMAN PERIPHERAL BLOOD T-LYMPHOCYTES.THE ACCURATE POSITION OF STIMULATED LYMPHOCYTES IN THE CELL CYCLE WAS DETERMINED BY USING THE \"PREMATURE CHROMOSOME CONDENSATION\" METHOD (PCC), WHICH OFFERS THE POSSIBILITY OF STUDYING THE DISTRIBUTION OF LYMPHOCYTES IN G1, S AND G2 PHASES. THE RESULTS OF THIS STUDY SUPPORT THE ASPECT THAT THE CD2 GENE EXPRESSION SEEMS TO BE CONTROLLED BY A COMBINATION OF REGULATORY MECHANISMS WHICH ARE ACTIVE AT TRANSCRIPTIONAL, POST TRANSCRIPTIONAL AND POST TRANSLATIONAL LEVEL. THE POSSIBILITY OF REGULATORY MECHANISMS AT OTHER LEVELS TOO, CANNOT BE EXCLUDED. THE CD2 GENE IS ONE OF A LARGE GROUP OF PHA INDUCIBLE GENES. THE FLUCTUATION OF CD2-MRNA THROUGH THE CELL CYCLE SUGGESTS THAT CD2 GENE IS PROBABLY EXPRESSED IN A CELL CYCLE DEPENDENT MANNER (MAINLY THROUGH G1 PHASE). FURTHERMORE THE INCREASED EXPRESSION OF THE CD2 GENE (MULTILAYER ROSE BE USED AS A MARKER OF CELL CYCLE PROGRESSION IN THE TRANSITION OF T-LYMPHOCYTES FROM GO TO S PHASE.","ΣΚΟΠΟΣ ΑΥΤΗΣ ΤΗΣ ΕΡΓΑΣΙΑΣ ΗΤΑΝ Η ΜΕΛΕΤΗ ΤΟΥ ΚΥΤΤΑΡΙΚΟΥ ΚΥΚΛΟΥ ΚΑΙ ΤΗΣ ΡΥΘΜΙΣΗΣ ΤΗΣ ΕΚΦΡΑΣΗΣ ΤΟΥ CD2 ΓΟΝΙΔΙΟΥ ΣΕ ΔΙΕΓΕΡΜΕΝΑ ΜΕ PHA ΑΝΘΡΩΠΙΝΑ Τ-ΛΕΜΦΟΚΥΤΤΑΡΑ ΤΟΥΠΕΡΙΦΕΡΙΚΟΥ ΑΙΜΑΤΟΣ. Η ΑΚΡΙΒΗΣ ΘΕΣΗ ΤΟΥ ΔΙΕΓΕΡΜΕΝΟΥ ΛΕΜΦΟΚΥΤΤΑΡΟΥ ΜΕΣΑ ΣΤΟΝ ΚΥΤΤΑΡΙΚΟ ΚΥΚΛΟ ΠΡΟΣΔΙΟΡΙΣΤΗΚΕ ΜΕ ΤΗ ΜΕΘΟΔΟ ΤΗΣ \"ΠΡΟΩΡΗΣ ΧΡΩΜΟΣΩΜΑΤΙΚΗΣ ΣΥΜΠΥΚΝΩΣΗΣ\" Η ΟΠΟΙΑ ΔΙΝΕΙ ΤΗΝ ΔΥΝΑΤΟΤΗΤΑ ΝΑ ΜΕΛΕΤΗΘΕΙ Η ΚΑΤΑΝΟΜΗ ΤΩΝ ΛΕΜΦΟΚΥΤΤΑΡΩΝ ΣΤΙΣΥΠΟΦΑΣΕΙΣ ΤΗΣ G1 ΚΑΙ ΣΤΙΣ ΦΑΣΕΙΣ S KAI G2. ΤΑ ΑΠΟΤΕΛΕΣΜΑΤΑ ΑΥΤΗΣ ΤΗΣ ΜΕΛΕΤΗΣ ΥΠΟΣΤΗΡΙΖΟΥΝ ΤΗΝ ΑΠΟΨΗ ΟΤΙ Η ΕΚΦΡΑΣΗ ΤΟΥ CD2 ΓΟΝΙΔΙΟΥ ΦΑΙΝΕΤΑΙ ΝΑ ΕΛΕΓΧΕΤΑΙ ΑΠΟ ΕΝΑ ΣΥΝΔΙΑΣΜΟ ΡΥΘΜΙΣΤΙΚΩΝ ΜΗΧΑΝΙΣΜΩΝ ΠΟΥ ΔΡΟΥΝ ΣΕ ΜΕΤΑΓΡΑΦΙΚΗ, ΜΕΤΑ-ΜΕΤΑΓΡΑΦΙΚΟΚΑΙ ΜΕΤΑ-ΜΕΤΑΦΡΑΣΤΙΚΟ ΕΠΙΠΕΔΟ ΧΩΡΙΣ Ν'ΑΠΟΚΛΕΙΟΝΤΑΙ ΕΛΕΓΧΟΙ ΚΑΙ ΣΕ ΑΛΛΑ ΕΠΙΠΕΔΑ. ΤΟ CD2 ΓΟΝΙΔΙΟ ΑΝΗΚΕΙ ΣΤΗΝ ΟΜΑΔΑ ΓΟΝΙΔΙΩΝ ΤΩΝ Τ- ΛΕΜΦΟΚΥΤΤΑΡΩΝ ΠΟΥ ΕΝΕΡΓΟΠΟΙΟΥΝΤΑΙ ΚΑΤΟΠΙΝ ΔΙΕΓΕΡΣΗΣ ΤΟΥ ΚΥΤΤΑΡΟΥ ΜΕ ΡΗΑ. Η ΔΙΑΚΥΜΑΝΣΗ ΤΗΣ ΣΥΣΣΩΡΕΥΣΗΣ ΤΟΥ CD2-MRNA ΚΑΤΑ ΤΗ ΔΙΑΡΚΕΙΑ ΤΟΥ ΚΥΤΤΑΡΙΚΟΥ ΚΥΚΛΟΥ ΔΕΙΧΝΕΙ ΟΤΙ Η ΕΚΦΡΑΣΗ ΤΟΥ ΓΟΝΙΔΙΟΥ ΠΙΘΑΝΟΝ ΝΑ ΕΛΕΓΧΕΤΑΙ ΑΠΟ ΤΟΝ ΚΥΤΤΑΡΙΚΟ ΚΥΚΛΟ. ΕΠΙΠΛΕΟΝ Η ΑΥΞΗΜΕΝΗ ΕΚΦΡΑΣΗ ΤΟΥ ΓΟΝΙΔΙΟΥ CD2 (ΟΠΩΣ ΑΥΤΗ ΕΛΕΓΧΕΤΑΙ ΑΠΟ ΤΗΝ ΑΥΞΗΜΕΝΗ ΙΚΑΝΟΤΗΤΑ ΤΩΝ ΛΕΜΦΟΚΥΤΤΑΡΩΝ ΝΑ ΣΧΗΜΑΤΙΖΟΥΝ ΠΟΛΥΣΤΡΩΜΑΤΙΚΕΣ ΡΟΖΕΤΤΕΣ), ΜΠΟΡΕΙ ΝΑ ΧΡΗΣΙΜΟΠΟΙΗΘΕΙ ΣΑΝ ΔΕΙΚΤΗΣ ΕΛΕΓΧΟΥ ΤΗΣ ΠΡΟΟΔΟΥ ΤΟΥ ΛΕΜΦΟΚΥΤΤΑΡΟΥ ΜΕΣΑ ΣΤΟ ΚΥΤΤΑΡΙΚΟ ΚΥΚΛΟ ΚΑΙ ΚΥΡΙΩΣ ΝΑ ΔΙΑΠΙΣΤΩΘΕΙ Η ΜΕΤΑΒΑΣΗ ΤΟΥ ΚΥΤΤΑΡΟΥ ΑΠΟ ΤΗ ΦΑΣΗ ΗΡΕΜΙΑΣ (GO) ΣΤΗ ΦΑΣΗ ΣΥΝΘΕΣΗΣ (S)."],"dc:identifier":["10.12681/eadd/1755","http://hdl.handle.net/10442/hedi/1755"],"dc:language":["gre"],"dc:publisher":["National and Kapodistrian University of Athens","Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)"],"dc:subject":["CD2 ΓΟΝΙΔΙΟ","CD2 ΚΥΤΤΑΡΟΕΠΙΦΑΝΕΙΑΚΟ ΑΝΤΙΓΟΝΟ","ΑΝΘΡΩΠΙΝΑ Τ-ΛΕΜΦΟΚΥΤΤΑΡΑ","Γονιδιακή έκφραση","Γονιδιακή ρύθμιση","Ε-ΡΟΔΑΚΑΣ","Κυτταρικός κύκλος","ΠΡΟΩΡΗ ΧΡΩΜΟΣΩΜΑΤΙΚΗ ΣΥΜΠΥΚΝΩΣΗ","Φυτοαιμαγλουτινίνη (PHA)","CD2 CELL SURFACE ANTIGEN","CD2 GENE","Cell cycle","E-ROSETTE","Gene expression","Gene regulation","Human T-lympocytes","Phytohemagglutinin (PHA)","Premature chromosome condensation","Φυσικές Επιστήμες","Βιολογία","Natural Sciences","Biological Sciences"],"dc:title":["ΓΟΝΙΔΙΑΚΗ ΕΚΦΡΑΣΗ ΔΙΕΓΕΡΜΕΝΩΝ ΑΝΘΡΩΠΙΝΩΝ Τ-ΛΕΜΦΟΚΥΤΤΑΡΩΝ: ΡΥΘΜΙΣΗ ΤΗΣ ΕΚΦΡΑΣΗΣ ΤΟΥ ΓΟΝΙΔΙΟΥ 2 ΚΑΤΑ ΤΗ ΔΙΑΡΚΕΙΑ ΤΟΥ ΚΥΤΤΑΡΙΚΟΥ ΚΥΚΛΟΥ","GENE EXPRESSION IN STIMULATED HUMAN T-LYMPHOCYTES: REGULATION OF THE CD2 GENE EXPRESSION"],"dc:type":["PhD Thesis"]},"updated_at":"2026-07-24T02:25:05Z"}