ΜΕΛΕΤΗ ΤΩΝ ΧΗΜΙΚΩΝ ΣΥΣΤΑΤΙΚΩΝ ΤΟΥ ΦΥΤΟΥ CYCLAMEN GRAECUM L
THIS WORK CONCERNS THE STUDY OF CHEMICAL COMPOSITION OF THE TUBERS AND LEAVES OF THE CYCLAMEN GRACEUM L PLANT. FLAVONOIDS, SUGARS AND LIPIDS ARE THE MAIN CONSTITUENTS STUDIED. IN THE TUBERS SAPONINS, SAPOGENINS, TRITERPENIC ACIDS, STARCH, FREE AND BONDED SUGARS (ANABINOSE, WHAMNOSE, XYLOSE, FRUCTOSE, GLUCOSE, AND GALACTOSE), TANNINS, LEUCOANTOCYANIDIUS, CATEHINES, PHENOLIC ACIDS AND LIPIDS HAVE BEEN DETECTED BUT THE SEARCH FOR QUINONES WAS NEGATIVE. AMINO ACIDS AND FLAVONOIDS HAVE BEEN ALSO DETECTED IN THE TUBERS AS WELL AS IN THE LEAVES. IN THE TUBERS STEROLS, FATTY ACIDS AND FLAVONOIDS WERE IDENTIFIED USING CLASSICAL TECHNIQUES (PC,TLC,CC,HPLC,UV,IR,NMR,MS,GLC,HYDROLYSIS). THE FLAVONOIDS ARE FOUR GLUCOSIDES OF DIHYDROKAEMPFEROL (3-0- GALACTOSIDE, 3-0-GLU 3-0-GALACTOSYL-GLUCOSIDE AND 3-0-GLUCOSYL- GLUCOSIDE) AND THE QUENKETIN-3-0-GLUCO IN THE LEAVES HAVE BEEN IDENTIFIED THE FLAVONOIDS: QUERKETIN-3-0-GALACTOSIDE (HYPERIN) KAEMPFEROL-3-GLUCOSYL-RHAMNOSIDE, VICENIN-2, KAEMPFEROL, QUERCETIN, MYRICETIN AND FOUR FLAVONOIDS IN SMALLER AMOUNTS WHICH PRESUMABLY CAN BE IDENTIFIED TO WERE GOSSYPETINE-7-METHYL ETHER, 3',4',DI-04-ISOFLAVONE 7 METHYL ETHER, 8-OH- E. SOME TUBER EXTRACTS HAVE BEEN STUDIED FOR ANTICANCER ACTIVITY USING MICE IN WHICH ASCITES FLUID OF P388 LYMPHOCYTIC LEUKEMIA HAS BEEN IMPLANTED. MOST OF THE EXTRACTS WERE FOUND TO BE TOXIC, EXCEPT THE SAPONIN EXTRACT, WHICH FOUND TO INCREASE THE MEDIAN LIFE OF THE ANIMALS, IN LOW DOSES.
CHEMICAL COMPOSITION OF THE TUBERS, LEAVES, CYCLAMEN GRAECUM L, Fatty acids, Flavonoids, Sterols, SUGARS, ΚΥΚΛΑΜΙΝΟ ΕΛΛΗΝΙΚΟ (L), Σάκχαρα, ΣΤΕΡΟΛΕΣ, ΛΙΠΑΡΑ ΟΞΕΑ, Φλαβονοειδή, ΧΗΜΙΚΑ ΣΥΣΤΑΤΙΚΑ ΒΟΛΒΩΝ ΚΑΙ ΦΥΛΛΩΝ, Φυσικές Επιστήμες, Natural Sciences, Χημεία, Chemical Sciences
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