ΣΥΜΒΟΛΗ ΣΤΗ ΜΕΛΕΤΗ ΤΗΣ ΠΕΡΙΕΚΤΙΚΟΤΗΤΑΣ ΣΕ ΚΑΛΛΙΚΡΕΙΝΗ ΤΟΥ ΟΛΙΚΟΥ ΣΙΑΛΟΥ ΤΟΥ ΑΝΘΡΩΠΟΥ IN VIVO ΚΑΙ ΤΩΝ ΥΠΟΓΝΑΘΙΩΝ ΑΔΕΝΩΝ ΤΩΝ ΕΠΙΜΥΩΝ IN VITRO ΜΕΤΑ ΤΗ ΧΟΡΗΓΗΣΗ ΑΝΤΙΦΛΕΓΜΟΝΩΔΩΝ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΟΥΣΙΩΝ.
THE CONCENTRATION OF KALLIKREIN OF THE WHOLE SALIVA WAS STUDIED IN 20 PERSONS. BEFORE AND AFTER THE ADMINISTRATION OF TWO ANTINFLAMMATORY AGENTS (INDOMETHACIN, NIFLEUMIC ACID) AS WELL AS IN THE EXTRACTION OF THE SUBMANDIBULAR GLANDS OF 15 RATS AFTER THE ADMINISTRATION OF PHENYLBUTAZONE, DEXAMETHAZONE, INDOMETHACIN AND NIFLEUMIC ACID IN DIFFERENT MALARITIES. IN BOTH GROUPS THE RATES OF KALLIKREIN ARE CHARACTERIZED BY A QUICK DECREASE WHICH BEGINS IMMEDIATELY AFTER THE ADMINISTRATION OF THE ANTINFLAMMATORY AGENTS. IT IS CONCLUDED THAT: 1) THE USE OFTHE ANTINFLAMMATORY AGENTS IS RECOMMENDED BECAUSE THEY HAVE THE ABILITY TO REDUCE THE PRODUCTION OF THE ENZYME OF KALLIKREIN 2) THE SALIVARY GLANDS OF THE MAN HAVE AN IMPRESSIVE ABILITY TO REPRODUCE THE KALLIKREIN IN A SHORT PERIOD OF TIME 3) FURTHER STUDIES WILL INVESTIGATE EVERY AGENT WHICH INHIBITED OR REDUCED THE KALLIKREIN PRODUCTION, THEREFORE WITH ITS GENERAL USE OR ITS LOCAL APPLICATION THE INFLAMMATION SYMPTOMS WILL BE REDUCED.
Αντιφλεγμονώδεις ουσίες, Δεξαμεθαζόνη, Επίμυες, Ινδομεθακίνη, Καλλικρεΐνες, ΝΙΦΛΟΥΜΙΚΟΝ ΟΞΥ, ΣΙΑΛΟΣ, ΥΠΟΓΝΑΘΙΟΙ ΑΔΕΝΕΣ, Φαινυλβουταζόνη, ANTINFLAMMATORY AGENTS, DEXAMETHAZONE, Indomethacin, Kallikreins, NIFLUMIC ACID, Phenylbutazone, Rats, Saliva, SUBMAXILLARY GLANDS, Ιατρική και Επιστήμες Υγείας, Κλινική Ιατρική, Medical and Health Sciences, Clinical Medicine
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