{"id":{"repo_id":"greece","oai_identifier":"oai:10442/1224"},"canonical_url":"https://search.dev.ndltd.org/etd/greece/oai:10442/1224","repository":{"repo_id":"greece","name":"Greek National Archive of PhD Theses","base_url":"https://phdtheses.ekt.gr/eadd_oai/request"},"display":{"title":"ΠΟΡΕΙΕΣ ΣΥΝΘΕΣΕΩΣ ΚΑΙ ΗΜΙΣΥΝΘΕΣΕΩΣ ΝΕΩΝ ΑΝΤΙΒΙΟΤΙΚΩΝ 'Η ΑΝΑΛΟΓΩΝ ΤΟΥΣ","abstract":"SYNTHESIS OF 6'-N DERIVATIVES OF NEAMINE WITH ALANINE, PHENYLALANINE AND LYCINEAND THEIR ANTIBACTERIAL ACTIVITY. SYNTHESIS OF 1,3-DI-AMINO AND MONO AMINOACIDDERIVATIVES OF 2- DEOXYSTREPTAMINE (TO BE USED FOR MOUTA SYNTHESIS OF AMINOCYCLITOL ANTIBIOTICS). SYNTHESIS OF A 3-DEOXY- PROUMYCIN-AN ANTIFUNGAL AND ANTILEUKEMIC ANTIBIOTIC VIA 2H-PYRAN-3(6H)-ONE. MICHAEL ADDITION OF BENZYLAMINE TO 2H-PYRAN-3(6H)-ONES. RESOLYTION OF RACEMIC D, L 2H-PYRAN-E(6H)-ONES SEVERAL 6-HYDROXY-2H-PYRAN-3(6H)-ONES WERE ESTERIFIED WITH BOC-ALA-OH IN LIGH YIELD. SYNTHESIS OF D AND L SUGARS. SYNTHESIS OF L AND D ACULOSE.","abstract_html":"SYNTHESIS OF 6'-N DERIVATIVES OF NEAMINE WITH ALANINE, PHENYLALANINE AND LYCINEAND THEIR ANTIBACTERIAL ACTIVITY. SYNTHESIS OF 1,3-DI-AMINO AND MONO AMINOACIDDERIVATIVES OF 2- DEOXYSTREPTAMINE (TO BE USED FOR MOUTA SYNTHESIS OF AMINOCYCLITOL ANTIBIOTICS). SYNTHESIS OF A 3-DEOXY- PROUMYCIN-AN ANTIFUNGAL AND ANTILEUKEMIC ANTIBIOTIC VIA 2H-PYRAN-3(6H)-ONE. MICHAEL ADDITION OF BENZYLAMINE TO 2H-PYRAN-3(6H)-ONES. RESOLYTION OF RACEMIC D, L 2H-PYRAN-E(6H)-ONES SEVERAL 6-HYDROXY-2H-PYRAN-3(6H)-ONES WERE ESTERIFIED WITH BOC-ALA-OH IN LIGH YIELD. SYNTHESIS OF D AND L SUGARS. SYNTHESIS OF L AND D ACULOSE.","abstract_has_math":false,"creators":["Constantinou-Kokotou, Violeta","Κωνσταντίνου-Κόκοτου, Βιολέττα"],"institution":"Agricultural University of Athens","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1989,"date_issued":"1989","date_published":"1989","updated_at":"2026-07-24T02:24:49Z","subjects":["ΑΜΙΝΟΚΥΚΛΙΤΟΛΟ-ΑΝΤΙΒΙΟΤΙΚΑ (ΑΜΙΝΟΓΛΥΚΟΣΙΔΕΣ)","ΜΟΥΤΑΣΥΝΘΕΣΗ ΑΜΙΝΟΚΥΚΛΙΤΟΛΟ-ΑΝΤΙΒΙΟΤΙΚΩΝ","ΝΕΑΜΙΝΗ, 2-ΔΕΟΞΥΣΤΡΕΠΤΑΜΙΝΗ","ΟΠΤΙΚΩΣ ΕΝΕΡΓΟΙ ΣΥΝΘΕΣΕΙΣ","2-DEOXYSTREPTAMINE, ANTIBACTERIAL ACTIVITY","AMINOCYCLITOL ANTIBIOTICS-NEAMINE-MUTASYNTHESIS","BOTRYTIS CINEREA, S. SCLERETORIUM","MICHAEL ADDITION, RESOLUTION","Pseudomonas aeruginosa","SYNTHESIS OF D- AND L- SUGARS","Φυσικές Επιστήμες","Χημεία","Natural Sciences","Chemical Sciences"],"languages":["gre"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["10.12681/eadd/1224"],"render_values":[{"text":"10.12681/eadd/1224","href":"https://doi.org/10.12681/eadd/1224","code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/10442/hedi/1224","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Constantinou-Kokotou, Violeta","Κωνσταντίνου-Κόκοτου, Βιολέττα"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["1989"]},{"key":"dc:publisher","label":"Institution","values":["Agricultural University of Athens","Ανωτάτη Γεωπονική Σχολή Αθηνών"]},{"key":"dc:type","label":"Dc Type","values":["PhD Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["ΑΜΙΝΟΚΥΚΛΙΤΟΛΟ-ΑΝΤΙΒΙΟΤΙΚΑ (ΑΜΙΝΟΓΛΥΚΟΣΙΔΕΣ)","ΜΟΥΤΑΣΥΝΘΕΣΗ ΑΜΙΝΟΚΥΚΛΙΤΟΛΟ-ΑΝΤΙΒΙΟΤΙΚΩΝ","ΝΕΑΜΙΝΗ, 2-ΔΕΟΞΥΣΤΡΕΠΤΑΜΙΝΗ","ΟΠΤΙΚΩΣ ΕΝΕΡΓΟΙ ΣΥΝΘΕΣΕΙΣ","2-DEOXYSTREPTAMINE, ANTIBACTERIAL ACTIVITY","AMINOCYCLITOL ANTIBIOTICS-NEAMINE-MUTASYNTHESIS","BOTRYTIS CINEREA, S. SCLERETORIUM","MICHAEL ADDITION, RESOLUTION","Pseudomonas aeruginosa","SYNTHESIS OF D- AND L- SUGARS","Φυσικές Επιστήμες","Χημεία","Natural Sciences","Chemical Sciences"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["gre"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["10.12681/eadd/1224","http://hdl.handle.net/10442/hedi/1224"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["SYNTHESIS OF 6'-N DERIVATIVES OF NEAMINE WITH ALANINE, PHENYLALANINE AND LYCINEAND THEIR ANTIBACTERIAL ACTIVITY. SYNTHESIS OF 1,3-DI-AMINO AND MONO AMINOACIDDERIVATIVES OF 2- DEOXYSTREPTAMINE (TO BE USED FOR MOUTA SYNTHESIS OF AMINOCYCLITOL ANTIBIOTICS). SYNTHESIS OF A 3-DEOXY- PROUMYCIN-AN ANTIFUNGAL AND ANTILEUKEMIC ANTIBIOTIC VIA 2H-PYRAN-3(6H)-ONE. MICHAEL ADDITION OF BENZYLAMINE TO 2H-PYRAN-3(6H)-ONES. RESOLYTION OF RACEMIC D, L 2H-PYRAN-E(6H)-ONES SEVERAL 6-HYDROXY-2H-PYRAN-3(6H)-ONES WERE ESTERIFIED WITH BOC-ALA-OH IN LIGH YIELD. SYNTHESIS OF D AND L SUGARS. SYNTHESIS OF L AND D ACULOSE.","ΣΥΝΘΕΣΗ 6'-Ν ΠΑΡΑΓΩΓΩΝ ΝΕΑΜΙΝΗΣ ΜΕ H-RHE-OH, H-ALA-OH, H-LYS-OH Η ΕΝΑ ΣΤΑΔΙΟ, ΕΙΤΕ ΜΕΣΩ ΠΑΡΑΓΩΓΟΥ ΜΕ ΕΛΕΥΘΕΡΗ ΜΟΝΟ ΤΗΝ 6' ΑΜΙΝΟΜΑΔΑ. ΕΛΕΓΧΟΣ ΑΝΤΙΒΑΚΤΗΡΙΑΚΗΣ ΔΡΑΣΗΣ. ΣΥΝΘΕΣΗ ΜΟΝΟ ΚΑΙ ΔΙ ΠΑΡΑΓΩΓΩΝ-2-ΔΕΟΞΥΣΤΡΕΠΤΑΜΙΝΗΣ ΓΙΑ ΤΗΝ ΜΟΝΤΑΣΥΝΘΕΣΗ ΑΜΙΝΟΚΥΚΛΙΤΟΛΟ -ΑΝΤΙΒΙΟΤΙΚΩΝ. ΟΛΙΚΗ ΣΥΝΘΕΣΗ ΤΟΥ ΑΝΤΙΒΙΟΤΙΚΟΥ 3-ΔΕΟΞΥΠΡΟΥΜΥΚΙΝΗ. ΣΥΝΘΕΣΗ ΒΕΝΖΥΛΟΞΥ-ΠΑΡΑΓΩΓΩΝ 2Η-ΠΥΡΑΝ-3-(6Η)-ΟΝΩΝ ΣΥΝΘΕΣΗ ΚΑΙ ΜΕΛΕΤΗ ΠΡΟΙΟΝΤΩΝ ΠΡΟΣΘΗΚΗΣ MICHAEL (ΑΖΙΔΙΟΥ-ΒΕΝΖΥΛΑΜΙΝΗΣ ΣΤΙΣ 2Η- ΠΥΡΑΝ-3(6Η)-ΑΝΕΣ. ΣΥΝΘΕΣΗ 6-ΑΚΥΛΟΞΥ ΚΑΙ 6-ΑΚΥΛΑΜΙΝΟ ΠΑΡΑΓΩΓΩΝ 2Η- ΠΥΡΑΝ-3(6Η)-ΟΝΩΝ. ΔΙΑΧΩΡΙΣΜΟΣ ΟΠΤΙΚΩΝ ΑΝΤΙΠΟΔΩΝ ΡΑΚΑΜΙΑΚΩΝ 2Η- ΠΥΡΑΝ-3(6Η)-ΟΝΩ ΣΥΝΘΕΣΗ L ΚΑΙ D-ΑΚΟΥΛΟΖΗΣ ΧΡΗΣΙΜΟΤΗΣ ΣΤΗ ΣΥΝΘΕΣΗ D ΚΑΙ L ΣΑΚΧΑΡΩΝ."]},{"key":"dc:title","label":"Title","values":["ΠΟΡΕΙΕΣ ΣΥΝΘΕΣΕΩΣ ΚΑΙ ΗΜΙΣΥΝΘΕΣΕΩΣ ΝΕΩΝ ΑΝΤΙΒΙΟΤΙΚΩΝ 'Η ΑΝΑΛΟΓΩΝ ΤΟΥΣ"]}]}],"canonical_facts":{"dc:creator":["Constantinou-Kokotou, Violeta","Κωνσταντίνου-Κόκοτου, Βιολέττα"],"dc:date":["1989"],"dc:description":["SYNTHESIS OF 6'-N DERIVATIVES OF NEAMINE WITH ALANINE, PHENYLALANINE AND LYCINEAND THEIR ANTIBACTERIAL ACTIVITY. SYNTHESIS OF 1,3-DI-AMINO AND MONO AMINOACIDDERIVATIVES OF 2- DEOXYSTREPTAMINE (TO BE USED FOR MOUTA SYNTHESIS OF AMINOCYCLITOL ANTIBIOTICS). SYNTHESIS OF A 3-DEOXY- PROUMYCIN-AN ANTIFUNGAL AND ANTILEUKEMIC ANTIBIOTIC VIA 2H-PYRAN-3(6H)-ONE. MICHAEL ADDITION OF BENZYLAMINE TO 2H-PYRAN-3(6H)-ONES. RESOLYTION OF RACEMIC D, L 2H-PYRAN-E(6H)-ONES SEVERAL 6-HYDROXY-2H-PYRAN-3(6H)-ONES WERE ESTERIFIED WITH BOC-ALA-OH IN LIGH YIELD. SYNTHESIS OF D AND L SUGARS. SYNTHESIS OF L AND D ACULOSE.","ΣΥΝΘΕΣΗ 6'-Ν ΠΑΡΑΓΩΓΩΝ ΝΕΑΜΙΝΗΣ ΜΕ H-RHE-OH, H-ALA-OH, H-LYS-OH Η ΕΝΑ ΣΤΑΔΙΟ, ΕΙΤΕ ΜΕΣΩ ΠΑΡΑΓΩΓΟΥ ΜΕ ΕΛΕΥΘΕΡΗ ΜΟΝΟ ΤΗΝ 6' ΑΜΙΝΟΜΑΔΑ. ΕΛΕΓΧΟΣ ΑΝΤΙΒΑΚΤΗΡΙΑΚΗΣ ΔΡΑΣΗΣ. ΣΥΝΘΕΣΗ ΜΟΝΟ ΚΑΙ ΔΙ ΠΑΡΑΓΩΓΩΝ-2-ΔΕΟΞΥΣΤΡΕΠΤΑΜΙΝΗΣ ΓΙΑ ΤΗΝ ΜΟΝΤΑΣΥΝΘΕΣΗ ΑΜΙΝΟΚΥΚΛΙΤΟΛΟ -ΑΝΤΙΒΙΟΤΙΚΩΝ. ΟΛΙΚΗ ΣΥΝΘΕΣΗ ΤΟΥ ΑΝΤΙΒΙΟΤΙΚΟΥ 3-ΔΕΟΞΥΠΡΟΥΜΥΚΙΝΗ. ΣΥΝΘΕΣΗ ΒΕΝΖΥΛΟΞΥ-ΠΑΡΑΓΩΓΩΝ 2Η-ΠΥΡΑΝ-3-(6Η)-ΟΝΩΝ ΣΥΝΘΕΣΗ ΚΑΙ ΜΕΛΕΤΗ ΠΡΟΙΟΝΤΩΝ ΠΡΟΣΘΗΚΗΣ MICHAEL (ΑΖΙΔΙΟΥ-ΒΕΝΖΥΛΑΜΙΝΗΣ ΣΤΙΣ 2Η- ΠΥΡΑΝ-3(6Η)-ΑΝΕΣ. ΣΥΝΘΕΣΗ 6-ΑΚΥΛΟΞΥ ΚΑΙ 6-ΑΚΥΛΑΜΙΝΟ ΠΑΡΑΓΩΓΩΝ 2Η- ΠΥΡΑΝ-3(6Η)-ΟΝΩΝ. ΔΙΑΧΩΡΙΣΜΟΣ ΟΠΤΙΚΩΝ ΑΝΤΙΠΟΔΩΝ ΡΑΚΑΜΙΑΚΩΝ 2Η- ΠΥΡΑΝ-3(6Η)-ΟΝΩ ΣΥΝΘΕΣΗ L ΚΑΙ D-ΑΚΟΥΛΟΖΗΣ ΧΡΗΣΙΜΟΤΗΣ ΣΤΗ ΣΥΝΘΕΣΗ D ΚΑΙ L ΣΑΚΧΑΡΩΝ."],"dc:identifier":["10.12681/eadd/1224","http://hdl.handle.net/10442/hedi/1224"],"dc:language":["gre"],"dc:publisher":["Agricultural University of Athens","Ανωτάτη Γεωπονική Σχολή Αθηνών"],"dc:subject":["ΑΜΙΝΟΚΥΚΛΙΤΟΛΟ-ΑΝΤΙΒΙΟΤΙΚΑ (ΑΜΙΝΟΓΛΥΚΟΣΙΔΕΣ)","ΜΟΥΤΑΣΥΝΘΕΣΗ ΑΜΙΝΟΚΥΚΛΙΤΟΛΟ-ΑΝΤΙΒΙΟΤΙΚΩΝ","ΝΕΑΜΙΝΗ, 2-ΔΕΟΞΥΣΤΡΕΠΤΑΜΙΝΗ","ΟΠΤΙΚΩΣ ΕΝΕΡΓΟΙ ΣΥΝΘΕΣΕΙΣ","2-DEOXYSTREPTAMINE, ANTIBACTERIAL ACTIVITY","AMINOCYCLITOL ANTIBIOTICS-NEAMINE-MUTASYNTHESIS","BOTRYTIS CINEREA, S. SCLERETORIUM","MICHAEL ADDITION, RESOLUTION","Pseudomonas aeruginosa","SYNTHESIS OF D- AND L- SUGARS","Φυσικές Επιστήμες","Χημεία","Natural Sciences","Chemical Sciences"],"dc:title":["ΠΟΡΕΙΕΣ ΣΥΝΘΕΣΕΩΣ ΚΑΙ ΗΜΙΣΥΝΘΕΣΕΩΣ ΝΕΩΝ ΑΝΤΙΒΙΟΤΙΚΩΝ 'Η ΑΝΑΛΟΓΩΝ ΤΟΥΣ"],"dc:type":["PhD Thesis"]},"updated_at":"2026-07-24T02:24:49Z"}