{"id":{"repo_id":"greece","oai_identifier":"oai:10442/1208"},"canonical_url":"https://search.dev.ndltd.org/etd/greece/oai:10442/1208","repository":{"repo_id":"greece","name":"Greek National Archive of PhD Theses","base_url":"https://phdtheses.ekt.gr/eadd_oai/request"},"display":{"title":"ΜΟΡΦΟΛΟΓΙΚΗ ΚΑΙ ΑΝΟΣΟΙΣΤΟΧΗΜΙΚΗ ΜΕΛΕΤΗ ΤΗΣ ΝΟΣΟΥ ΤΟΥ HODGKIN, ΣΥΓΚΡΙΤΙΚΗ ΣΤΙΣ ΔΙΑΦΟΡΕΣ ΜΟΡΦΕΣ","abstract":"FORTY-TWO CASES OF HODGKIN'S DISEASE WERE STUDIED MORPHOLOGICALLY AND IMMUNOHISTOCHEMICALLY BY USING MONOCLONAL ANTIBODIES MAINLY AGAINST KI-1, LEUM1, EMA, LCA, L26 AND VCHL1. NO SIMILAR STUDY HAS BEEN DONE PREVIOUSLY IN GREECE. THE WHOLE NUMBER OF STUDIES APPLIED IN B-CELL MARKERS ON LYMPHOCYTE PREDOMINANT HODGKIN'S DISEASE IS ALSO VERY LIMITED. ALL OF THEM WERE DONE ON PARAFFIN SECTIONS. INOUR PRESENT STUDY CRYOSTAT SECTIONS WERE ADDITIONALLY USED IN PART OF THE CASES. THE USE OF L26, A PAN B-ANTIGEN, HAS BEEN RECENTLY INTRODUCED IN IMMUNOHISTOPATHOLOGY. OUR STUDY WAS THE FIRST TO APPLIED THIS ANTIGEN IN IMMUNOHISTOCHEMICAL EVALUATION AND IDENTIFICATION OF THE NEOPLASTIC CELLS IN LYMPHOCYTE PREDOMINANT TYPE. IT IS CONCLUDED THAT SOME MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL FEATURES DO EXIST, HELPING WITH THE PREDICTION OF THE POSSIBLE PROGRESSION OF THE LYMPHOCYTE PREDOMINANT HODGKIN'S DISEASE TOWARD A HIGH GRADE MALIGNANT LYMPHOMA. THE INCLUDED AGGREGATION OF L AND H CELLS INTERMINGLED WITH CELLS OF CENTROBLASTIC AND/OR IMMUNOBLASTIC TYPE AS WELL AS NEGATIVITY FOR LEUM1 AND KI-1 AND POSITIVITY FOR L26 AND LCA ANTIGENS. NEGATIVITY FOR KI-1 ANTIGEN IN PARAFFIN SECTIONS MUST BE ACCEPTED WITH RESERVE IMMUNOHISTOCHEMICAL IDENTIFICATION OF KI-1 PHENOTYPE OF NEOPLASTIC CELLS IN LYMPHOCYTE PREDOMINANT TYPE DEMANDS THE USAGE OF CRYOSTAT SECTIONS.","abstract_html":"FORTY-TWO CASES OF HODGKIN'S DISEASE WERE STUDIED MORPHOLOGICALLY AND IMMUNOHISTOCHEMICALLY BY USING MONOCLONAL ANTIBODIES MAINLY AGAINST KI-1, LEUM1, EMA, LCA, L26 AND VCHL1. NO SIMILAR STUDY HAS BEEN DONE PREVIOUSLY IN GREECE. THE WHOLE NUMBER OF STUDIES APPLIED IN B-CELL MARKERS ON LYMPHOCYTE PREDOMINANT HODGKIN'S DISEASE IS ALSO VERY LIMITED. ALL OF THEM WERE DONE ON PARAFFIN SECTIONS. INOUR PRESENT STUDY CRYOSTAT SECTIONS WERE ADDITIONALLY USED IN PART OF THE CASES. THE USE OF L26, A PAN B-ANTIGEN, HAS BEEN RECENTLY INTRODUCED IN IMMUNOHISTOPATHOLOGY. OUR STUDY WAS THE FIRST TO APPLIED THIS ANTIGEN IN IMMUNOHISTOCHEMICAL EVALUATION AND IDENTIFICATION OF THE NEOPLASTIC CELLS IN LYMPHOCYTE PREDOMINANT TYPE. IT IS CONCLUDED THAT SOME MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL FEATURES DO EXIST, HELPING WITH THE PREDICTION OF THE POSSIBLE PROGRESSION OF THE LYMPHOCYTE PREDOMINANT HODGKIN'S DISEASE TOWARD A HIGH GRADE MALIGNANT LYMPHOMA. THE INCLUDED AGGREGATION OF L AND H CELLS INTERMINGLED WITH CELLS OF CENTROBLASTIC AND/OR IMMUNOBLASTIC TYPE AS WELL AS NEGATIVITY FOR LEUM1 AND KI-1 AND POSITIVITY FOR L26 AND LCA ANTIGENS. NEGATIVITY FOR KI-1 ANTIGEN IN PARAFFIN SECTIONS MUST BE ACCEPTED WITH RESERVE IMMUNOHISTOCHEMICAL IDENTIFICATION OF KI-1 PHENOTYPE OF NEOPLASTIC CELLS IN LYMPHOCYTE PREDOMINANT TYPE DEMANDS THE USAGE OF CRYOSTAT SECTIONS.","abstract_has_math":false,"creators":["Kostopoulos, Ioannis","Κωστόπουλος, Ιωάννης"],"institution":"University of Ioannina","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1989,"date_issued":"1989","date_published":"1989","updated_at":"2026-07-24T02:24:46Z","subjects":["ΛΕΜΦΟΕΠΙΚΡΑΤΙΚΟΣ ΤΥΠΟΣ (ΟΖΩΔΗΣ, ΔΙΑΧΥΤΟΣ)","Νόσος Hodgkin","Hodgkin's disease","LYMPHOCYTE PREDOMINANT TYPE (NODULAR, DIFFUSE)","Ιατρική και Επιστήμες Υγείας","Κλινική Ιατρική","Medical and Health Sciences","Clinical Medicine"],"languages":["gre"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["10.12681/eadd/1208"],"render_values":[{"text":"10.12681/eadd/1208","href":"https://doi.org/10.12681/eadd/1208","code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/10442/hedi/1208","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Kostopoulos, Ioannis","Κωστόπουλος, Ιωάννης"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["1989"]},{"key":"dc:publisher","label":"Institution","values":["University of Ioannina","Πανεπιστήμιο Ιωαννίνων"]},{"key":"dc:type","label":"Dc Type","values":["PhD Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["ΛΕΜΦΟΕΠΙΚΡΑΤΙΚΟΣ ΤΥΠΟΣ (ΟΖΩΔΗΣ, ΔΙΑΧΥΤΟΣ)","Νόσος Hodgkin","Hodgkin's disease","LYMPHOCYTE PREDOMINANT TYPE (NODULAR, DIFFUSE)","Ιατρική και Επιστήμες Υγείας","Κλινική Ιατρική","Medical and Health Sciences","Clinical Medicine"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["gre"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["10.12681/eadd/1208","http://hdl.handle.net/10442/hedi/1208"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["FORTY-TWO CASES OF HODGKIN'S DISEASE WERE STUDIED MORPHOLOGICALLY AND IMMUNOHISTOCHEMICALLY BY USING MONOCLONAL ANTIBODIES MAINLY AGAINST KI-1, LEUM1, EMA, LCA, L26 AND VCHL1. NO SIMILAR STUDY HAS BEEN DONE PREVIOUSLY IN GREECE. THE WHOLE NUMBER OF STUDIES APPLIED IN B-CELL MARKERS ON LYMPHOCYTE PREDOMINANT HODGKIN'S DISEASE IS ALSO VERY LIMITED. ALL OF THEM WERE DONE ON PARAFFIN SECTIONS. INOUR PRESENT STUDY CRYOSTAT SECTIONS WERE ADDITIONALLY USED IN PART OF THE CASES. THE USE OF L26, A PAN B-ANTIGEN, HAS BEEN RECENTLY INTRODUCED IN IMMUNOHISTOPATHOLOGY. OUR STUDY WAS THE FIRST TO APPLIED THIS ANTIGEN IN IMMUNOHISTOCHEMICAL EVALUATION AND IDENTIFICATION OF THE NEOPLASTIC CELLS IN LYMPHOCYTE PREDOMINANT TYPE. IT IS CONCLUDED THAT SOME MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL FEATURES DO EXIST, HELPING WITH THE PREDICTION OF THE POSSIBLE PROGRESSION OF THE LYMPHOCYTE PREDOMINANT HODGKIN'S DISEASE TOWARD A HIGH GRADE MALIGNANT LYMPHOMA. THE INCLUDED AGGREGATION OF L AND H CELLS INTERMINGLED WITH CELLS OF CENTROBLASTIC AND/OR IMMUNOBLASTIC TYPE AS WELL AS NEGATIVITY FOR LEUM1 AND KI-1 AND POSITIVITY FOR L26 AND LCA ANTIGENS. NEGATIVITY FOR KI-1 ANTIGEN IN PARAFFIN SECTIONS MUST BE ACCEPTED WITH RESERVE IMMUNOHISTOCHEMICAL IDENTIFICATION OF KI-1 PHENOTYPE OF NEOPLASTIC CELLS IN LYMPHOCYTE PREDOMINANT TYPE DEMANDS THE USAGE OF CRYOSTAT SECTIONS.","ΜΕΛΕΤΗΘΗΚΑΝ 42 ΠΕΡΙΠΤΩΣΕΙΣ ΝΟΣΟΥ ΤΟΥ HODGKIN ΜΟΡΦΟΛΟΓΙΚΑ ΚΑΙ ΑΝΟΣΟΙΣΤΟΛΟΓΙΚΑ ΧΡΗΣΙΜΟΠΟΙΩΝΤΑΣ ΤΑ ΜΟΝΟΚΛΩΝΙΚΑ ΑΝΤΙΣΩΜΑΤΑ ANTI-KI -1, LEUM1, ANTI EMA, ANTI-LCA, LZ6 ΚΑΙ UCHL1. ΑΝΑΛΟΓΗ ΕΡΓΑΣΙΑ ΣΤΗΝ ΕΛΛΑΔΑ ΓΙΝΕΤΑΙ ΓΙΑ ΠΡΩΤΗ ΦΟΡΑ ΔΙΕΘΝΩΣ Η ΧΡΗΣΗ Β-ΚΥΤΤΑΡΙΚΩΝ ΔΕΙΚΤΩΝ ΣΤΟΝ ΛΕΜΦΟΕΠΙΚΡΑΤΗΤΙΚΟ ΤΥΠΟ ΤΗΣ ΝΟΣΟΥ ΤΟΥ HODGKIN ΕΙΝΑΙΠΕΡΙΟΡΙΣΜΕΝΗ. ΟΛΕΣ ΑΦΟΡΟΥΝ ΤΟΜΕΣ ΠΑΡΑΦΙΝΗΣ. ΣΤΗΝ ΕΡΓΑΣΙΑ ΜΑΣ ΧΡΗΣΙΜΟΠΟΙΗΘΗΚΑΝ ΣΕ ΜΕΡΟΣ ΤΩΝ ΠΕΡΙΠΤΩΣΕΩΝ ΚΑΙ ΤΟΜΕΣ ΚΡΥΟΣΤΑΤΗ. ΤΟ Β-ΚΥΤΤΑΡΙΚΟ ΑΝΤΙΓΟΝΟ L26 ΧΡΗΣΙΜΟΠΟΙΗΘΗΚΕ ΠΡΟΣΦΑΤΑ ΚΑΙ ΚΥΡΙΩΣ ΣΤΗΝ ΔΙΚΗ ΜΑΣ ΕΡΓΑΣΙΑ ΠΟΥ ΑΠΟΤΕΛΕΙ ΣΥΜΒΟΛΗ ΣΤΗΝ ΑΞΙΟΛΟΓΗΣΗ ΚΑΙ ΑΞΙΟΠΟΙΗΣΗ ΤΟΥ ΕΝ ΛΟΓΩ ΑΝΤΙΓΟΝΟΥ ΣΕ ΣΧΕΣΗ ΜΕ ΤΗΝ ΤΑΥΤΟΠΟΙΗΣΗ ΤΩΝΝΕΟΠΛΑΣΜΑΤΙΚΩΝ ΚΥΤΤΑΡΩΝ ΤΟΥ ΛΕΜΦΟΕΠΙΚΡΑΤΗΤΙΚΟΥ ΤΥΠΟΥ. ΑΠΟ ΤΗΝ ΕΡΓΑΣΙΑ ΜΑΣ ΣΥΝΑΓΕΤΑΙ ΟΤΙ ΥΠΑΡΧΟΥΝ ΟΡΙΣΜΕΝΟΙ ΜΟΡΦΟΛΟΓΙΚΟΙ ΚΑΙ ΑΝΟΣΟΙΣΤΟΧΗΜΙΚΟΙ ΧΑΡΑΚΤΗΡΕΣ ΠΟΥ ΜΠΟΡΟΥΝ ΝΑ ΠΡΟΔΙΚΑΣΟΥΝ ΤΗΝ ΠΙΘΑΝΗ ΕΞΕΛΙΞΗ ΤΟΥ ΛΕΜΦΟΕΠΙΚΡΑΤΗΤΙΚΟΥ ΤΥΠΟΥ ΠΡΟΣ ΕΝΑ ΥΨΗΛΗΣ ΚΑΚΟΗΘΕΙΑΣ ΛΕΜΦΩΜΑ. ΑΥΤΗ ΕΙΝΑΙ Η ΣΥΓΚΕΝΤΡΩΣΗ ΚΥΤΤΑΡΩΝ ΛΕΜΦΟΕΠΙΚΡΑΤΥΠΟΥ ΚΑΙ Η ΑΝΑΜΙΞΗ ΤΟΥΣ ΜΕ ΚΥΤΤΑΡΑ ΚΕΝΤΡΟΒΛΑΣΤΙΚΟΥ 'Η ΑΝΟΣΟΒΛΑΣΤΙΚΟΥ ΤΥΠΟΥ, Η ΑΡΝΗΤΙΚΟΤΗΤΑ ΣΤΑ ΑΝΤΙΓΟΝΑ LEUM1 ΚΑΙ ΚΙ-1 ΚΑΙ ΘΕΤΙΚΟΤΗΤΑ ΣΤΑ L26 ΚΑΙ LCA. ΑΡΝΗΤΙΚΟΤΗΤΑ ΣΤΟ ΑΝΤΙΓΟΝΟ KI-1 ΣΕ ΤΟΜΕΣ ΠΑΡΑΦΙΝΗΣ ΠΡΕΠΕΙ ΝΑ ΓΙΝΕΤΑΙ ΔΕΚΤΗ ΜΕ ΕΠΙΦΥΛΑΞΗ. Ο ΚΑΘΟΡΙΣΜΟΣ ΤΟΥ ΑΝΟΣΟΙΣΤΟΧΗΜΙΚΟΥ ΦΑΙΝΟΤΥΠΟΥ ΣΕ ΟΤΙ ΑΦΟΡΑ ΤΟ ΑΝΤΙΓΟΝΟ ΚΙ-1 ΣΤΙΣ ΔΙΑΦΟΡΕΣ ΜΟΡΦΕΣ ΤΟΥ ΛΕΜΦΟΕΠΙΚΡΑΤΗΤΙΚΟΥ ΤΥΠΟΥ ΑΠΑΙΤΕΙ ΕΚΤΕΤΑΜΕΝΗ ΧΡΗΣΙΜΟΠΟΙΗΣΗ ΤΟΜΩΝ ΚΡΥΟΣΤΑΤΗ, ΓΕΓΟΝΟΣ ΠΟΥ ΔΕΝ ΕΧΕΙ ΕΦΑΡΜΟΣΘΕΙ ΣΤΙΣ ΜΕΧΡΙ ΤΩΡΑ ΜΕΛΕΤΕΣ."]},{"key":"dc:title","label":"Title","values":["ΜΟΡΦΟΛΟΓΙΚΗ ΚΑΙ ΑΝΟΣΟΙΣΤΟΧΗΜΙΚΗ ΜΕΛΕΤΗ ΤΗΣ ΝΟΣΟΥ ΤΟΥ HODGKIN, ΣΥΓΚΡΙΤΙΚΗ ΣΤΙΣ ΔΙΑΦΟΡΕΣ ΜΟΡΦΕΣ"]}]}],"canonical_facts":{"dc:creator":["Kostopoulos, Ioannis","Κωστόπουλος, Ιωάννης"],"dc:date":["1989"],"dc:description":["FORTY-TWO CASES OF HODGKIN'S DISEASE WERE STUDIED MORPHOLOGICALLY AND IMMUNOHISTOCHEMICALLY BY USING MONOCLONAL ANTIBODIES MAINLY AGAINST KI-1, LEUM1, EMA, LCA, L26 AND VCHL1. NO SIMILAR STUDY HAS BEEN DONE PREVIOUSLY IN GREECE. THE WHOLE NUMBER OF STUDIES APPLIED IN B-CELL MARKERS ON LYMPHOCYTE PREDOMINANT HODGKIN'S DISEASE IS ALSO VERY LIMITED. ALL OF THEM WERE DONE ON PARAFFIN SECTIONS. INOUR PRESENT STUDY CRYOSTAT SECTIONS WERE ADDITIONALLY USED IN PART OF THE CASES. THE USE OF L26, A PAN B-ANTIGEN, HAS BEEN RECENTLY INTRODUCED IN IMMUNOHISTOPATHOLOGY. OUR STUDY WAS THE FIRST TO APPLIED THIS ANTIGEN IN IMMUNOHISTOCHEMICAL EVALUATION AND IDENTIFICATION OF THE NEOPLASTIC CELLS IN LYMPHOCYTE PREDOMINANT TYPE. IT IS CONCLUDED THAT SOME MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL FEATURES DO EXIST, HELPING WITH THE PREDICTION OF THE POSSIBLE PROGRESSION OF THE LYMPHOCYTE PREDOMINANT HODGKIN'S DISEASE TOWARD A HIGH GRADE MALIGNANT LYMPHOMA. THE INCLUDED AGGREGATION OF L AND H CELLS INTERMINGLED WITH CELLS OF CENTROBLASTIC AND/OR IMMUNOBLASTIC TYPE AS WELL AS NEGATIVITY FOR LEUM1 AND KI-1 AND POSITIVITY FOR L26 AND LCA ANTIGENS. NEGATIVITY FOR KI-1 ANTIGEN IN PARAFFIN SECTIONS MUST BE ACCEPTED WITH RESERVE IMMUNOHISTOCHEMICAL IDENTIFICATION OF KI-1 PHENOTYPE OF NEOPLASTIC CELLS IN LYMPHOCYTE PREDOMINANT TYPE DEMANDS THE USAGE OF CRYOSTAT SECTIONS.","ΜΕΛΕΤΗΘΗΚΑΝ 42 ΠΕΡΙΠΤΩΣΕΙΣ ΝΟΣΟΥ ΤΟΥ HODGKIN ΜΟΡΦΟΛΟΓΙΚΑ ΚΑΙ ΑΝΟΣΟΙΣΤΟΛΟΓΙΚΑ ΧΡΗΣΙΜΟΠΟΙΩΝΤΑΣ ΤΑ ΜΟΝΟΚΛΩΝΙΚΑ ΑΝΤΙΣΩΜΑΤΑ ANTI-KI -1, LEUM1, ANTI EMA, ANTI-LCA, LZ6 ΚΑΙ UCHL1. ΑΝΑΛΟΓΗ ΕΡΓΑΣΙΑ ΣΤΗΝ ΕΛΛΑΔΑ ΓΙΝΕΤΑΙ ΓΙΑ ΠΡΩΤΗ ΦΟΡΑ ΔΙΕΘΝΩΣ Η ΧΡΗΣΗ Β-ΚΥΤΤΑΡΙΚΩΝ ΔΕΙΚΤΩΝ ΣΤΟΝ ΛΕΜΦΟΕΠΙΚΡΑΤΗΤΙΚΟ ΤΥΠΟ ΤΗΣ ΝΟΣΟΥ ΤΟΥ HODGKIN ΕΙΝΑΙΠΕΡΙΟΡΙΣΜΕΝΗ. ΟΛΕΣ ΑΦΟΡΟΥΝ ΤΟΜΕΣ ΠΑΡΑΦΙΝΗΣ. ΣΤΗΝ ΕΡΓΑΣΙΑ ΜΑΣ ΧΡΗΣΙΜΟΠΟΙΗΘΗΚΑΝ ΣΕ ΜΕΡΟΣ ΤΩΝ ΠΕΡΙΠΤΩΣΕΩΝ ΚΑΙ ΤΟΜΕΣ ΚΡΥΟΣΤΑΤΗ. ΤΟ Β-ΚΥΤΤΑΡΙΚΟ ΑΝΤΙΓΟΝΟ L26 ΧΡΗΣΙΜΟΠΟΙΗΘΗΚΕ ΠΡΟΣΦΑΤΑ ΚΑΙ ΚΥΡΙΩΣ ΣΤΗΝ ΔΙΚΗ ΜΑΣ ΕΡΓΑΣΙΑ ΠΟΥ ΑΠΟΤΕΛΕΙ ΣΥΜΒΟΛΗ ΣΤΗΝ ΑΞΙΟΛΟΓΗΣΗ ΚΑΙ ΑΞΙΟΠΟΙΗΣΗ ΤΟΥ ΕΝ ΛΟΓΩ ΑΝΤΙΓΟΝΟΥ ΣΕ ΣΧΕΣΗ ΜΕ ΤΗΝ ΤΑΥΤΟΠΟΙΗΣΗ ΤΩΝΝΕΟΠΛΑΣΜΑΤΙΚΩΝ ΚΥΤΤΑΡΩΝ ΤΟΥ ΛΕΜΦΟΕΠΙΚΡΑΤΗΤΙΚΟΥ ΤΥΠΟΥ. ΑΠΟ ΤΗΝ ΕΡΓΑΣΙΑ ΜΑΣ ΣΥΝΑΓΕΤΑΙ ΟΤΙ ΥΠΑΡΧΟΥΝ ΟΡΙΣΜΕΝΟΙ ΜΟΡΦΟΛΟΓΙΚΟΙ ΚΑΙ ΑΝΟΣΟΙΣΤΟΧΗΜΙΚΟΙ ΧΑΡΑΚΤΗΡΕΣ ΠΟΥ ΜΠΟΡΟΥΝ ΝΑ ΠΡΟΔΙΚΑΣΟΥΝ ΤΗΝ ΠΙΘΑΝΗ ΕΞΕΛΙΞΗ ΤΟΥ ΛΕΜΦΟΕΠΙΚΡΑΤΗΤΙΚΟΥ ΤΥΠΟΥ ΠΡΟΣ ΕΝΑ ΥΨΗΛΗΣ ΚΑΚΟΗΘΕΙΑΣ ΛΕΜΦΩΜΑ. ΑΥΤΗ ΕΙΝΑΙ Η ΣΥΓΚΕΝΤΡΩΣΗ ΚΥΤΤΑΡΩΝ ΛΕΜΦΟΕΠΙΚΡΑΤΥΠΟΥ ΚΑΙ Η ΑΝΑΜΙΞΗ ΤΟΥΣ ΜΕ ΚΥΤΤΑΡΑ ΚΕΝΤΡΟΒΛΑΣΤΙΚΟΥ 'Η ΑΝΟΣΟΒΛΑΣΤΙΚΟΥ ΤΥΠΟΥ, Η ΑΡΝΗΤΙΚΟΤΗΤΑ ΣΤΑ ΑΝΤΙΓΟΝΑ LEUM1 ΚΑΙ ΚΙ-1 ΚΑΙ ΘΕΤΙΚΟΤΗΤΑ ΣΤΑ L26 ΚΑΙ LCA. ΑΡΝΗΤΙΚΟΤΗΤΑ ΣΤΟ ΑΝΤΙΓΟΝΟ KI-1 ΣΕ ΤΟΜΕΣ ΠΑΡΑΦΙΝΗΣ ΠΡΕΠΕΙ ΝΑ ΓΙΝΕΤΑΙ ΔΕΚΤΗ ΜΕ ΕΠΙΦΥΛΑΞΗ. Ο ΚΑΘΟΡΙΣΜΟΣ ΤΟΥ ΑΝΟΣΟΙΣΤΟΧΗΜΙΚΟΥ ΦΑΙΝΟΤΥΠΟΥ ΣΕ ΟΤΙ ΑΦΟΡΑ ΤΟ ΑΝΤΙΓΟΝΟ ΚΙ-1 ΣΤΙΣ ΔΙΑΦΟΡΕΣ ΜΟΡΦΕΣ ΤΟΥ ΛΕΜΦΟΕΠΙΚΡΑΤΗΤΙΚΟΥ ΤΥΠΟΥ ΑΠΑΙΤΕΙ ΕΚΤΕΤΑΜΕΝΗ ΧΡΗΣΙΜΟΠΟΙΗΣΗ ΤΟΜΩΝ ΚΡΥΟΣΤΑΤΗ, ΓΕΓΟΝΟΣ ΠΟΥ ΔΕΝ ΕΧΕΙ ΕΦΑΡΜΟΣΘΕΙ ΣΤΙΣ ΜΕΧΡΙ ΤΩΡΑ ΜΕΛΕΤΕΣ."],"dc:identifier":["10.12681/eadd/1208","http://hdl.handle.net/10442/hedi/1208"],"dc:language":["gre"],"dc:publisher":["University of Ioannina","Πανεπιστήμιο Ιωαννίνων"],"dc:subject":["ΛΕΜΦΟΕΠΙΚΡΑΤΙΚΟΣ ΤΥΠΟΣ (ΟΖΩΔΗΣ, ΔΙΑΧΥΤΟΣ)","Νόσος Hodgkin","Hodgkin's disease","LYMPHOCYTE PREDOMINANT TYPE (NODULAR, DIFFUSE)","Ιατρική και Επιστήμες Υγείας","Κλινική Ιατρική","Medical and Health Sciences","Clinical Medicine"],"dc:title":["ΜΟΡΦΟΛΟΓΙΚΗ ΚΑΙ ΑΝΟΣΟΙΣΤΟΧΗΜΙΚΗ ΜΕΛΕΤΗ ΤΗΣ ΝΟΣΟΥ ΤΟΥ HODGKIN, ΣΥΓΚΡΙΤΙΚΗ ΣΤΙΣ ΔΙΑΦΟΡΕΣ ΜΟΡΦΕΣ"],"dc:type":["PhD Thesis"]},"updated_at":"2026-07-24T02:24:46Z"}