{"id":{"repo_id":"greece","oai_identifier":"oai:10442/0497"},"canonical_url":"https://search.dev.ndltd.org/etd/greece/oai:10442/0497","repository":{"repo_id":"greece","name":"Greek National Archive of PhD Theses","base_url":"https://phdtheses.ekt.gr/eadd_oai/request"},"display":{"title":"ΣΥΜΒΟΛΗ ΣΤΗ ΜΕΛΕΤΗ ΚΑΙ ΤΟ ΧΑΡΑΚΤΗΡΙΣΜΟ ΤΗΣ ΕΞΩΚΥΤΤΑΡΙΑΣ ΟΥΣΙΑΣ (SLIME) ΒΑΚΤΗΡΙΑΙΜΙΚΟΥ ΒΛΕΝΝΩΔΟΥΣ ΚΑΙ ΘΥΓΑΤΡΙΚΟΥ ΜΗ ΒΛΕΝΝΩΔΟΥΣ ΣΤΕΛΕΧΟΥΣ PSEUDOMONAS AERUGINOSA","abstract":"THE FIRST CASE OF A HEAVILY MUCOID STRAIN (MS) OR PSEUDOMONAS AERUGINOSA BACTEREMIA IS REPORTED IN A HOSPITALIZED 78-YR-OLD WOMAN WITH DRUG-INDUCED HEPATITIS DUE TO ANTITUBERCULOUS THERAPY. A REVERTANT NON MUCOID VARIANT (RNMV) FROM THE PARENTAL MS WAS OBTAINED BY SERIAL PASSAGE ON TRYPTICASE SOY AGAR. THE EXTRACELLULAR MATERIAL (SLIME) FROM BOTH STRAINS WAS EXTRACTED BY METHODS AS FOR THE EXTRACTION OF GLYCOLIPOPROTEIN (GLP). GROSS CHEMICAL ANALYSES OF THE MS'S AND RNMV'S SLIME FOR URONIC ACIDS, CARBOHYDRATES, PROTEINS AND LIPIDS WERE 65%, 5.5%, 1.0%, 0.9% AND 16%, 48%, 11% AND 2% OF DRY WEIGHT, RESPECTIVELY. ANTIBODIES TO THE EXTRACELLULAR MATERIAL OF BOTH STRAINS WERE RAISED IN NEW ZEALAND WHITE RABBITS AND CROSS REACTIVITY IN HIGH TITERS AMONG THEM WAS SHOWN BY PASSIVE HEMAGGLUTINATION. ALSO, IT WAS SHOWN THAT THE EXTRACELLULAR MATERIAL OF THE RNMV EXERTED MITOGENIC ACTIVITY ON HUMAN PERIPHERAL LYMPHOCYTES WHILE THE MS'S EXTRACELLULAR MATERIAL WAS NOT MITOGENIC. THE MAJOR COMPONENT OF THE MS'S SLIME WAS ISOLATED BY ION EXCHANGE CHROMATOGRAPHY (IEC) AND GEL FILTRATION. IT WAS CHARACTERIZED, BY GELATINIZATION WITH CACL2, VISCOCITY MEASUREMENTS AND INFRARED SPECTROSCOPY, AS ALGINATE OF HIGH MOLECULAR WEIGHT, SIMILAR TO THAT PRODUCED BY MUCOID P.AERUGINOSA STRAINS FROM CYSTIC FIBROSIS. UNDER THE SAME CONDITIONS, IEC OF THE RNMV'S MATERIAL REVEALED TWO MAJOR PEAKS OF WHICH THE FIRST WAS COMPOSED OF NEUTRAL SUGARS (NS) AND PROTEIN IN ABOUT 5:1 RATIO, AND THE SECOND WAS CONSISTEDOF BOTH NS AND URONIC ACIDS. THIS URONIC ACID WAS SEPARATED FROM THE NS MOIETYBY PRECIPITATION WITH CACL2 AND WAS ALSO CHARACTERIZED AS ALGINATE BY INFRAREDSPECTROSCOPY. UREA -SDS- POLYACRYLAMIDE GEL ELECTROPHORESIS SHOWED THAT THE CELLS OF BOTH MUCOID AND NON MUCOID P.AERUGINOSA STRAINS CONTAIN SMOOTH LIPOPOLYSACCHARID THE RNMV'S SLIME DID NOT BEHAVE AS LIPOPOLYSACCHARIDE AS SHOWN BY UREA-SDS POLYACRYLAMIDE ELECTROPHORESIS AND BY LIMULUS AMOEBOCYTE LYSATE PYROTEST.","abstract_html":"THE FIRST CASE OF A HEAVILY MUCOID STRAIN (MS) OR PSEUDOMONAS AERUGINOSA BACTEREMIA IS REPORTED IN A HOSPITALIZED 78-YR-OLD WOMAN WITH DRUG-INDUCED HEPATITIS DUE TO ANTITUBERCULOUS THERAPY. A REVERTANT NON MUCOID VARIANT (RNMV) FROM THE PARENTAL MS WAS OBTAINED BY SERIAL PASSAGE ON TRYPTICASE SOY AGAR. THE EXTRACELLULAR MATERIAL (SLIME) FROM BOTH STRAINS WAS EXTRACTED BY METHODS AS FOR THE EXTRACTION OF GLYCOLIPOPROTEIN (GLP). GROSS CHEMICAL ANALYSES OF THE MS'S AND RNMV'S SLIME FOR URONIC ACIDS, CARBOHYDRATES, PROTEINS AND LIPIDS WERE 65%, 5.5%, 1.0%, 0.9% AND 16%, 48%, 11% AND 2% OF DRY WEIGHT, RESPECTIVELY. ANTIBODIES TO THE EXTRACELLULAR MATERIAL OF BOTH STRAINS WERE RAISED IN NEW ZEALAND WHITE RABBITS AND CROSS REACTIVITY IN HIGH TITERS AMONG THEM WAS SHOWN BY PASSIVE HEMAGGLUTINATION. ALSO, IT WAS SHOWN THAT THE EXTRACELLULAR MATERIAL OF THE RNMV EXERTED MITOGENIC ACTIVITY ON HUMAN PERIPHERAL LYMPHOCYTES WHILE THE MS'S EXTRACELLULAR MATERIAL WAS NOT MITOGENIC. THE MAJOR COMPONENT OF THE MS'S SLIME WAS ISOLATED BY ION EXCHANGE CHROMATOGRAPHY (IEC) AND GEL FILTRATION. IT WAS CHARACTERIZED, BY GELATINIZATION WITH CACL2, VISCOCITY MEASUREMENTS AND INFRARED SPECTROSCOPY, AS ALGINATE OF HIGH MOLECULAR WEIGHT, SIMILAR TO THAT PRODUCED BY MUCOID P.AERUGINOSA STRAINS FROM CYSTIC FIBROSIS. UNDER THE SAME CONDITIONS, IEC OF THE RNMV'S MATERIAL REVEALED TWO MAJOR PEAKS OF WHICH THE FIRST WAS COMPOSED OF NEUTRAL SUGARS (NS) AND PROTEIN IN ABOUT 5:1 RATIO, AND THE SECOND WAS CONSISTEDOF BOTH NS AND URONIC ACIDS. THIS URONIC ACID WAS SEPARATED FROM THE NS MOIETYBY PRECIPITATION WITH CACL2 AND WAS ALSO CHARACTERIZED AS ALGINATE BY INFRAREDSPECTROSCOPY. UREA -SDS- POLYACRYLAMIDE GEL ELECTROPHORESIS SHOWED THAT THE CELLS OF BOTH MUCOID AND NON MUCOID P.AERUGINOSA STRAINS CONTAIN SMOOTH LIPOPOLYSACCHARID THE RNMV'S SLIME DID NOT BEHAVE AS LIPOPOLYSACCHARIDE AS SHOWN BY UREA-SDS POLYACRYLAMIDE ELECTROPHORESIS AND BY LIMULUS AMOEBOCYTE LYSATE PYROTEST.","abstract_has_math":false,"creators":["Anastassiou, Evangelos","Αναστασίου, Ευάγγελος"],"institution":"University of Patras","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1987,"date_issued":"1987","date_published":"1987","updated_at":"2026-07-24T02:25:17Z","subjects":["ΑΛΓΙΝΙΚΟ","Βακτηριαιμίες","ΒΛΕΝΝΩΔΕΣ ΣΤΕΛΕΧΟΣ","Γλυκολιποπρωτεϊνη","ΕΞΟΚΥΤΤΑΡΙΑ ΟΥΣΙΑ","ΛΙΠΟΠΟΛΥΣΑΚΧΑΡΙΤΕΣ","Alginate","Bacteremia","GLYCOLIPOPROTEIN GLP","LIPOPOLYSACCHARIDE","MUCOID STRAIN","Pseudomonas aeruginosa","Slime","Ιατρική και Επιστήμες Υγείας","Κλινική Ιατρική","Medical and Health Sciences","Clinical Medicine"],"languages":["gre"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["10.12681/eadd/0497"],"render_values":[{"text":"10.12681/eadd/0497","href":"https://doi.org/10.12681/eadd/0497","code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/10442/hedi/0497","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Anastassiou, Evangelos","Αναστασίου, Ευάγγελος"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["1987"]},{"key":"dc:publisher","label":"Institution","values":["University of Patras","Πανεπιστήμιο Πατρών"]},{"key":"dc:type","label":"Dc Type","values":["PhD Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["ΑΛΓΙΝΙΚΟ","Βακτηριαιμίες","ΒΛΕΝΝΩΔΕΣ ΣΤΕΛΕΧΟΣ","Γλυκολιποπρωτεϊνη","ΕΞΟΚΥΤΤΑΡΙΑ ΟΥΣΙΑ","ΛΙΠΟΠΟΛΥΣΑΚΧΑΡΙΤΕΣ","Alginate","Bacteremia","GLYCOLIPOPROTEIN GLP","LIPOPOLYSACCHARIDE","MUCOID STRAIN","Pseudomonas aeruginosa","Slime","Ιατρική και Επιστήμες Υγείας","Κλινική Ιατρική","Medical and Health Sciences","Clinical Medicine"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["gre"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["10.12681/eadd/0497","http://hdl.handle.net/10442/hedi/0497"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["THE FIRST CASE OF A HEAVILY MUCOID STRAIN (MS) OR PSEUDOMONAS AERUGINOSA BACTEREMIA IS REPORTED IN A HOSPITALIZED 78-YR-OLD WOMAN WITH DRUG-INDUCED HEPATITIS DUE TO ANTITUBERCULOUS THERAPY. A REVERTANT NON MUCOID VARIANT (RNMV) FROM THE PARENTAL MS WAS OBTAINED BY SERIAL PASSAGE ON TRYPTICASE SOY AGAR. THE EXTRACELLULAR MATERIAL (SLIME) FROM BOTH STRAINS WAS EXTRACTED BY METHODS AS FOR THE EXTRACTION OF GLYCOLIPOPROTEIN (GLP). GROSS CHEMICAL ANALYSES OF THE MS'S AND RNMV'S SLIME FOR URONIC ACIDS, CARBOHYDRATES, PROTEINS AND LIPIDS WERE 65%, 5.5%, 1.0%, 0.9% AND 16%, 48%, 11% AND 2% OF DRY WEIGHT, RESPECTIVELY. ANTIBODIES TO THE EXTRACELLULAR MATERIAL OF BOTH STRAINS WERE RAISED IN NEW ZEALAND WHITE RABBITS AND CROSS REACTIVITY IN HIGH TITERS AMONG THEM WAS SHOWN BY PASSIVE HEMAGGLUTINATION. ALSO, IT WAS SHOWN THAT THE EXTRACELLULAR MATERIAL OF THE RNMV EXERTED MITOGENIC ACTIVITY ON HUMAN PERIPHERAL LYMPHOCYTES WHILE THE MS'S EXTRACELLULAR MATERIAL WAS NOT MITOGENIC. THE MAJOR COMPONENT OF THE MS'S SLIME WAS ISOLATED BY ION EXCHANGE CHROMATOGRAPHY (IEC) AND GEL FILTRATION. IT WAS CHARACTERIZED, BY GELATINIZATION WITH CACL2, VISCOCITY MEASUREMENTS AND INFRARED SPECTROSCOPY, AS ALGINATE OF HIGH MOLECULAR WEIGHT, SIMILAR TO THAT PRODUCED BY MUCOID P.AERUGINOSA STRAINS FROM CYSTIC FIBROSIS. UNDER THE SAME CONDITIONS, IEC OF THE RNMV'S MATERIAL REVEALED TWO MAJOR PEAKS OF WHICH THE FIRST WAS COMPOSED OF NEUTRAL SUGARS (NS) AND PROTEIN IN ABOUT 5:1 RATIO, AND THE SECOND WAS CONSISTEDOF BOTH NS AND URONIC ACIDS. THIS URONIC ACID WAS SEPARATED FROM THE NS MOIETYBY PRECIPITATION WITH CACL2 AND WAS ALSO CHARACTERIZED AS ALGINATE BY INFRAREDSPECTROSCOPY. UREA -SDS- POLYACRYLAMIDE GEL ELECTROPHORESIS SHOWED THAT THE CELLS OF BOTH MUCOID AND NON MUCOID P.AERUGINOSA STRAINS CONTAIN SMOOTH LIPOPOLYSACCHARID THE RNMV'S SLIME DID NOT BEHAVE AS LIPOPOLYSACCHARIDE AS SHOWN BY UREA-SDS POLYACRYLAMIDE ELECTROPHORESIS AND BY LIMULUS AMOEBOCYTE LYSATE PYROTEST.","ΑΝΑΦΕΡΕΤΑΙ ΓΙΑ ΠΡΩΤΗ ΦΟΡΑ ΣΤΗ ΒΙΒΛΙΟΓΡΑΦΙΑ Η ΑΠΟΜΟΝΩΣΗ ΠΟΛΥ ΒΛΕΝΝΩΔΟΥΣ ΣΤΕΛΕΧΟΥΣ PSEUDOMONAS AERUGINOSA ΑΠΟ ΚΑΛΛΙΕΡΓΕΙΕΣ ΑΙΜΑΤΟΣ. Η ΕΞΩΚΥΤΤΑΡΙΑ ΟΥΣΙΑ (SLIME) ΤΟΥ ΜΗΤΡΙΚΟΥ ΒΛΕΝΝΩΔΟΥΣ ΣΤΕΛΕΧΟΥΣ (ΜΒΣ) ΧΑΡΑΚΤΗΡΙΣΘΗΚΕ ΩΣ ΑΛΓΙΝΙΚΟ ΥΨΗΛΟΥ ΜΟΡΙΑΚΟΥ ΒΑΡΟΥΣ . ΑΠΟ ΤΟ ΜΒΣ ΠΑΡΑΛΗΦΘΗΚΕ ΜΕΤΑ ΑΠΟ ΣΥΝΕΧΕΙΣ IN VITRO ΑΝΑΚΑΛΛΙΕΡΓΕΙΕΣ ΘΥΓΑΤΡΙΚΟ ΜΗ ΒΛΕΝΝΩΔΕΣ ΣΤΕΛΕΧΟΣ (ΘΜΒΣ) ΑΠΟ ΤΟ ΟΠΟΙΟ ΑΠΟΜΟΝΩΘΗΚΕ ΕΞΩΚΥΤΤΑΡΙΑ ΟΥΣΙΑ Η ΟΠΟΙΑ ΑΠΟΤΕΛΕΙΤΟ ΑΠΟ ΟΥΡΟΝΙΚΑ ΟΞΕΑ (16%), ΥΔΑΤΑΝΘΡΑΚΕΣ (48%), ΠΡΩΤΕΙΝΗ (11%) ΚΑΙ ΛΙΠΗ (2%). Η ΕΞΩΚΥΤΤΑΡΙΑ ΟΥΣΙΑ ΤΟΥ ΘΜΒΣ ΧΑΡΑΚΤΗΡΙΣΘΗΚΕ ΩΣ ΑΝΑΛΟΓΗ ΤΗΣ ΓΛΥΚΟΛΙΠΟΠΡΩΤΕΙΝΗΣ (GLP) ΤΟΥ SLIME ΠΟΥ ΑΠΟΜΟΝΩΝΕΤΑΙ ΚΑΙ ΑΠΟ ΤΟΥΣ ΕΠΤΑ ΑΝΟΣΟΤΥΠΟΥΣΤΟΥ FISHER. Η ΕΞΩΚΥΤΤΑΡΙΑ ΟΥΣΙΑ ΤΟΥ ΜΒΣ ΔΕΝ ΕΞΑΣΚΕΙ ΜΙΤΟΓΟΝΟ ΔΡΑΣΗ ΣΕ ΑΝΘΡΩΠΙΝΑ ΠΕΡΙΦΕΡΙΚΑ ΛΕΜΦΟΚΥΤΤΑΡΑ, ΥΠΑΡΧΟΥΝ ΔΙΑΣΤΑΥΡΟΥΜΕΝΕΣ ΑΝΟΣΟΛΟΓΙΚΕΣ ΑΝΤΙΔΡΑΣΕΙΣ ΜΕΤΑΞΥ ΤΩΝ ΕΞΩΚΥΤΤΑΡΙΩΝ ΟΥΣΙΩΝ ΤΟΥ ΜΒΣ ΚΑΙ ΘΜΒΣ ΕΝΩ ΚΑΙ ΤΑ ΔΥΟ ΣΤΕΛΕΧΗ ΑΠΟΤΕΛΟΥΝΤΑΙ ΑΠΟ SMOOTH ΤΥΠΟ ΛΙΠΟΠΟΛΥΣΑΚΧΑΡΙΤΗ. Η ΕΞΩΚΥΤΤΑΡΙΑ ΟΥΣΙΑ (GLP) ΤΟΥ ΘΜΒΣ ΠΕΡΙΕΧΕΙ ΜΙΚΡΑ ΠΟΣΑ ΑΛΓΙΝΙΚΟΥ."]},{"key":"dc:title","label":"Title","values":["ΣΥΜΒΟΛΗ ΣΤΗ ΜΕΛΕΤΗ ΚΑΙ ΤΟ ΧΑΡΑΚΤΗΡΙΣΜΟ ΤΗΣ ΕΞΩΚΥΤΤΑΡΙΑΣ ΟΥΣΙΑΣ (SLIME) ΒΑΚΤΗΡΙΑΙΜΙΚΟΥ ΒΛΕΝΝΩΔΟΥΣ ΚΑΙ ΘΥΓΑΤΡΙΚΟΥ ΜΗ ΒΛΕΝΝΩΔΟΥΣ ΣΤΕΛΕΧΟΥΣ PSEUDOMONAS AERUGINOSA","CHARACTERIZATION OF THE EXTRACELLULAR MATERIAL (SLIME) OF A HEAVILY MUCOID STRAIN OF PSEUDOMONAS AERUGINOSA ISOLATED FROM BLOOD CULTURES AND OF ITS REVERTANT NONMUCOID VARIANT"]}]}],"canonical_facts":{"dc:creator":["Anastassiou, Evangelos","Αναστασίου, Ευάγγελος"],"dc:date":["1987"],"dc:description":["THE FIRST CASE OF A HEAVILY MUCOID STRAIN (MS) OR PSEUDOMONAS AERUGINOSA BACTEREMIA IS REPORTED IN A HOSPITALIZED 78-YR-OLD WOMAN WITH DRUG-INDUCED HEPATITIS DUE TO ANTITUBERCULOUS THERAPY. A REVERTANT NON MUCOID VARIANT (RNMV) FROM THE PARENTAL MS WAS OBTAINED BY SERIAL PASSAGE ON TRYPTICASE SOY AGAR. THE EXTRACELLULAR MATERIAL (SLIME) FROM BOTH STRAINS WAS EXTRACTED BY METHODS AS FOR THE EXTRACTION OF GLYCOLIPOPROTEIN (GLP). GROSS CHEMICAL ANALYSES OF THE MS'S AND RNMV'S SLIME FOR URONIC ACIDS, CARBOHYDRATES, PROTEINS AND LIPIDS WERE 65%, 5.5%, 1.0%, 0.9% AND 16%, 48%, 11% AND 2% OF DRY WEIGHT, RESPECTIVELY. ANTIBODIES TO THE EXTRACELLULAR MATERIAL OF BOTH STRAINS WERE RAISED IN NEW ZEALAND WHITE RABBITS AND CROSS REACTIVITY IN HIGH TITERS AMONG THEM WAS SHOWN BY PASSIVE HEMAGGLUTINATION. ALSO, IT WAS SHOWN THAT THE EXTRACELLULAR MATERIAL OF THE RNMV EXERTED MITOGENIC ACTIVITY ON HUMAN PERIPHERAL LYMPHOCYTES WHILE THE MS'S EXTRACELLULAR MATERIAL WAS NOT MITOGENIC. THE MAJOR COMPONENT OF THE MS'S SLIME WAS ISOLATED BY ION EXCHANGE CHROMATOGRAPHY (IEC) AND GEL FILTRATION. IT WAS CHARACTERIZED, BY GELATINIZATION WITH CACL2, VISCOCITY MEASUREMENTS AND INFRARED SPECTROSCOPY, AS ALGINATE OF HIGH MOLECULAR WEIGHT, SIMILAR TO THAT PRODUCED BY MUCOID P.AERUGINOSA STRAINS FROM CYSTIC FIBROSIS. UNDER THE SAME CONDITIONS, IEC OF THE RNMV'S MATERIAL REVEALED TWO MAJOR PEAKS OF WHICH THE FIRST WAS COMPOSED OF NEUTRAL SUGARS (NS) AND PROTEIN IN ABOUT 5:1 RATIO, AND THE SECOND WAS CONSISTEDOF BOTH NS AND URONIC ACIDS. THIS URONIC ACID WAS SEPARATED FROM THE NS MOIETYBY PRECIPITATION WITH CACL2 AND WAS ALSO CHARACTERIZED AS ALGINATE BY INFRAREDSPECTROSCOPY. UREA -SDS- POLYACRYLAMIDE GEL ELECTROPHORESIS SHOWED THAT THE CELLS OF BOTH MUCOID AND NON MUCOID P.AERUGINOSA STRAINS CONTAIN SMOOTH LIPOPOLYSACCHARID THE RNMV'S SLIME DID NOT BEHAVE AS LIPOPOLYSACCHARIDE AS SHOWN BY UREA-SDS POLYACRYLAMIDE ELECTROPHORESIS AND BY LIMULUS AMOEBOCYTE LYSATE PYROTEST.","ΑΝΑΦΕΡΕΤΑΙ ΓΙΑ ΠΡΩΤΗ ΦΟΡΑ ΣΤΗ ΒΙΒΛΙΟΓΡΑΦΙΑ Η ΑΠΟΜΟΝΩΣΗ ΠΟΛΥ ΒΛΕΝΝΩΔΟΥΣ ΣΤΕΛΕΧΟΥΣ PSEUDOMONAS AERUGINOSA ΑΠΟ ΚΑΛΛΙΕΡΓΕΙΕΣ ΑΙΜΑΤΟΣ. Η ΕΞΩΚΥΤΤΑΡΙΑ ΟΥΣΙΑ (SLIME) ΤΟΥ ΜΗΤΡΙΚΟΥ ΒΛΕΝΝΩΔΟΥΣ ΣΤΕΛΕΧΟΥΣ (ΜΒΣ) ΧΑΡΑΚΤΗΡΙΣΘΗΚΕ ΩΣ ΑΛΓΙΝΙΚΟ ΥΨΗΛΟΥ ΜΟΡΙΑΚΟΥ ΒΑΡΟΥΣ . ΑΠΟ ΤΟ ΜΒΣ ΠΑΡΑΛΗΦΘΗΚΕ ΜΕΤΑ ΑΠΟ ΣΥΝΕΧΕΙΣ IN VITRO ΑΝΑΚΑΛΛΙΕΡΓΕΙΕΣ ΘΥΓΑΤΡΙΚΟ ΜΗ ΒΛΕΝΝΩΔΕΣ ΣΤΕΛΕΧΟΣ (ΘΜΒΣ) ΑΠΟ ΤΟ ΟΠΟΙΟ ΑΠΟΜΟΝΩΘΗΚΕ ΕΞΩΚΥΤΤΑΡΙΑ ΟΥΣΙΑ Η ΟΠΟΙΑ ΑΠΟΤΕΛΕΙΤΟ ΑΠΟ ΟΥΡΟΝΙΚΑ ΟΞΕΑ (16%), ΥΔΑΤΑΝΘΡΑΚΕΣ (48%), ΠΡΩΤΕΙΝΗ (11%) ΚΑΙ ΛΙΠΗ (2%). Η ΕΞΩΚΥΤΤΑΡΙΑ ΟΥΣΙΑ ΤΟΥ ΘΜΒΣ ΧΑΡΑΚΤΗΡΙΣΘΗΚΕ ΩΣ ΑΝΑΛΟΓΗ ΤΗΣ ΓΛΥΚΟΛΙΠΟΠΡΩΤΕΙΝΗΣ (GLP) ΤΟΥ SLIME ΠΟΥ ΑΠΟΜΟΝΩΝΕΤΑΙ ΚΑΙ ΑΠΟ ΤΟΥΣ ΕΠΤΑ ΑΝΟΣΟΤΥΠΟΥΣΤΟΥ FISHER. Η ΕΞΩΚΥΤΤΑΡΙΑ ΟΥΣΙΑ ΤΟΥ ΜΒΣ ΔΕΝ ΕΞΑΣΚΕΙ ΜΙΤΟΓΟΝΟ ΔΡΑΣΗ ΣΕ ΑΝΘΡΩΠΙΝΑ ΠΕΡΙΦΕΡΙΚΑ ΛΕΜΦΟΚΥΤΤΑΡΑ, ΥΠΑΡΧΟΥΝ ΔΙΑΣΤΑΥΡΟΥΜΕΝΕΣ ΑΝΟΣΟΛΟΓΙΚΕΣ ΑΝΤΙΔΡΑΣΕΙΣ ΜΕΤΑΞΥ ΤΩΝ ΕΞΩΚΥΤΤΑΡΙΩΝ ΟΥΣΙΩΝ ΤΟΥ ΜΒΣ ΚΑΙ ΘΜΒΣ ΕΝΩ ΚΑΙ ΤΑ ΔΥΟ ΣΤΕΛΕΧΗ ΑΠΟΤΕΛΟΥΝΤΑΙ ΑΠΟ SMOOTH ΤΥΠΟ ΛΙΠΟΠΟΛΥΣΑΚΧΑΡΙΤΗ. Η ΕΞΩΚΥΤΤΑΡΙΑ ΟΥΣΙΑ (GLP) ΤΟΥ ΘΜΒΣ ΠΕΡΙΕΧΕΙ ΜΙΚΡΑ ΠΟΣΑ ΑΛΓΙΝΙΚΟΥ."],"dc:identifier":["10.12681/eadd/0497","http://hdl.handle.net/10442/hedi/0497"],"dc:language":["gre"],"dc:publisher":["University of Patras","Πανεπιστήμιο Πατρών"],"dc:subject":["ΑΛΓΙΝΙΚΟ","Βακτηριαιμίες","ΒΛΕΝΝΩΔΕΣ ΣΤΕΛΕΧΟΣ","Γλυκολιποπρωτεϊνη","ΕΞΟΚΥΤΤΑΡΙΑ ΟΥΣΙΑ","ΛΙΠΟΠΟΛΥΣΑΚΧΑΡΙΤΕΣ","Alginate","Bacteremia","GLYCOLIPOPROTEIN GLP","LIPOPOLYSACCHARIDE","MUCOID STRAIN","Pseudomonas aeruginosa","Slime","Ιατρική και Επιστήμες Υγείας","Κλινική Ιατρική","Medical and Health Sciences","Clinical Medicine"],"dc:title":["ΣΥΜΒΟΛΗ ΣΤΗ ΜΕΛΕΤΗ ΚΑΙ ΤΟ ΧΑΡΑΚΤΗΡΙΣΜΟ ΤΗΣ ΕΞΩΚΥΤΤΑΡΙΑΣ ΟΥΣΙΑΣ (SLIME) ΒΑΚΤΗΡΙΑΙΜΙΚΟΥ ΒΛΕΝΝΩΔΟΥΣ ΚΑΙ ΘΥΓΑΤΡΙΚΟΥ ΜΗ ΒΛΕΝΝΩΔΟΥΣ ΣΤΕΛΕΧΟΥΣ PSEUDOMONAS AERUGINOSA","CHARACTERIZATION OF THE EXTRACELLULAR MATERIAL (SLIME) OF A HEAVILY MUCOID STRAIN OF PSEUDOMONAS AERUGINOSA ISOLATED FROM BLOOD CULTURES AND OF ITS REVERTANT NONMUCOID VARIANT"],"dc:type":["PhD Thesis"]},"updated_at":"2026-07-24T02:25:17Z"}