{"id":{"repo_id":"greece","oai_identifier":"oai:10442/0448"},"canonical_url":"https://search.dev.ndltd.org/etd/greece/oai:10442/0448","repository":{"repo_id":"greece","name":"Greek National Archive of PhD Theses","base_url":"https://phdtheses.ekt.gr/eadd_oai/request"},"display":{"title":"ΔΙΑΤΑΡΑΧΕΣ ΤΩΝ ΑΝΟΣΟΣΦΑΙΡΙΝΩΝ ΣΤΑ ΚΑΚΟΗΘΗ ΜΗ HODGKIN'S ΛΕΜΦΩΜΑΤΑ ΑΠΟ Β ΚΥΤΤΑΡΑ","abstract":"THIS WORK DEALS WITH THE STUDY OF SERUM AND URINE OF 76 CASES WITH B- NON HODGKIN'S LYMPHOMA, ACCORDING TO THE CRITERIA OF LUKES AND COLLINS, FOR THE DETECTION OF MONOCLONAL IMMUNOGLOBULINS. QUANTITATION OF SERUM IMMUNOGLOBULINS, DETECTION OF CRYOGLOBULINS AND INVESTIGATION OF THE MONOCLONAL IMMUNOGLOBULINS FOR AUTOANTIBODY SPECIFICITIES, WAS ALSO PERFORMED. THE OVERALL INCIDENCE OF MONOCLONAL IMMUNOGLOBULINS IN THESE PATIENTS WAS 25%. THE FREQUENCY OF THE DIFFERENT CATEGORIES OF B-NHL WAS AS FOLLOWS: CHRONIC LYMPHOMATIC LEUKAEMIA (CLL) 4%. FOLLICULAR CENTER CELL LYMPHOMAS (FCC) 11,7%, B-IMMUNOBLASTIC LYMPHOMA 40%, SMALL LYMPHOCYTIC LYMPHOMA (SLL) 41,6% AND PLASMACYTOID LYMPHOCYTIC LYMPHOMA 58,3%. HYPOGAMMAGLOBULINAEMIA WAS MORE FREQUENT IN CLL AND SLL. BENCE-JONES PROTEINS WAS FOUND IN 5 CASES. HIGH TITRE AUTOANTIBODIES WERE FOUND IN 4 PATIENTS WITH MONOCLONAL IMMUNOGLOBULINS.","abstract_html":"THIS WORK DEALS WITH THE STUDY OF SERUM AND URINE OF 76 CASES WITH B- NON HODGKIN'S LYMPHOMA, ACCORDING TO THE CRITERIA OF LUKES AND COLLINS, FOR THE DETECTION OF MONOCLONAL IMMUNOGLOBULINS. QUANTITATION OF SERUM IMMUNOGLOBULINS, DETECTION OF CRYOGLOBULINS AND INVESTIGATION OF THE MONOCLONAL IMMUNOGLOBULINS FOR AUTOANTIBODY SPECIFICITIES, WAS ALSO PERFORMED. THE OVERALL INCIDENCE OF MONOCLONAL IMMUNOGLOBULINS IN THESE PATIENTS WAS 25%. THE FREQUENCY OF THE DIFFERENT CATEGORIES OF B-NHL WAS AS FOLLOWS: CHRONIC LYMPHOMATIC LEUKAEMIA (CLL) 4%. FOLLICULAR CENTER CELL LYMPHOMAS (FCC) 11,7%, B-IMMUNOBLASTIC LYMPHOMA 40%, SMALL LYMPHOCYTIC LYMPHOMA (SLL) 41,6% AND PLASMACYTOID LYMPHOCYTIC LYMPHOMA 58,3%. HYPOGAMMAGLOBULINAEMIA WAS MORE FREQUENT IN CLL AND SLL. BENCE-JONES PROTEINS WAS FOUND IN 5 CASES. HIGH TITRE AUTOANTIBODIES WERE FOUND IN 4 PATIENTS WITH MONOCLONAL IMMUNOGLOBULINS.","abstract_has_math":false,"creators":["Καρατσοπάνη-Τερζόγλου, Κωνσταντίνα"],"institution":"National and Kapodistrian University of Athens","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1986,"date_issued":"1986","date_published":"1986","updated_at":"2026-07-24T02:25:17Z","subjects":["Ανοσοσφαιρίνες","Β-ΑΝΟΣΟΒΛΑΣΤΙΚΟ ΛΕΜΦΩΜΑ","Β-ΜΗ HODGKIN'S ΛΕΜΦΩΜΑΤΑ","ΛΕΜΦΩΜΑ ΑΠΟ ΚΥΤΤΑΡΑ ΤΟΥ ΒΛΑΣΤΙΚΟΥ ΚΕΝΤΡΟΥ","Λέμφωμα από μικρά λεμφοκύτταρα","ΛΕΜΦΩΜΑ ΑΠΟ ΠΛΑΣΜΑΤΟΚΥΤΤΑΡΟΕΙΔΗ ΛΕΜΦΟΚΥΤΤ ΥΠΟΓΑΜΜΑΣΦΑΙΡΙΝΑΙΜΙΑ","Μονοκλωνικές ανοσοσφαιρίνες","Λευχαιμία, Χρόνια λεμφική","B-IMMUNOBLASTIC LYMPHOMA","B - non Hodgkin's lymphomas","Chronic lymphocytic leukemia","FOLLICULAR CENTER CELL LYMPHOMA","HYPOGAMMAGLOBULINAEMIA","Immunoglobulins","Monoclonal immunoglobulins","PLASMACYTOID LYMPHOCYTIC LYMPHOMA","Small lymphocytic lymphoma","Ιατρική και Επιστήμες Υγείας","Κλινική Ιατρική","Medical and Health Sciences","Clinical Medicine"],"languages":["gre"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["10.12681/eadd/0448"],"render_values":[{"text":"10.12681/eadd/0448","href":"https://doi.org/10.12681/eadd/0448","code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/10442/hedi/0448","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Καρατσοπάνη-Τερζόγλου, Κωνσταντίνα"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["1986"]},{"key":"dc:publisher","label":"Institution","values":["National and Kapodistrian University of Athens","Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)"]},{"key":"dc:type","label":"Dc Type","values":["PhD Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Ανοσοσφαιρίνες","Β-ΑΝΟΣΟΒΛΑΣΤΙΚΟ ΛΕΜΦΩΜΑ","Β-ΜΗ HODGKIN'S ΛΕΜΦΩΜΑΤΑ","ΛΕΜΦΩΜΑ ΑΠΟ ΚΥΤΤΑΡΑ ΤΟΥ ΒΛΑΣΤΙΚΟΥ ΚΕΝΤΡΟΥ","Λέμφωμα από μικρά λεμφοκύτταρα","ΛΕΜΦΩΜΑ ΑΠΟ ΠΛΑΣΜΑΤΟΚΥΤΤΑΡΟΕΙΔΗ ΛΕΜΦΟΚΥΤΤ ΥΠΟΓΑΜΜΑΣΦΑΙΡΙΝΑΙΜΙΑ","Μονοκλωνικές ανοσοσφαιρίνες","Λευχαιμία, Χρόνια λεμφική","B-IMMUNOBLASTIC LYMPHOMA","B - non Hodgkin's lymphomas","Chronic lymphocytic leukemia","FOLLICULAR CENTER CELL LYMPHOMA","HYPOGAMMAGLOBULINAEMIA","Immunoglobulins","Monoclonal immunoglobulins","PLASMACYTOID LYMPHOCYTIC LYMPHOMA","Small lymphocytic lymphoma","Ιατρική και Επιστήμες Υγείας","Κλινική Ιατρική","Medical and Health Sciences","Clinical Medicine"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["gre"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["10.12681/eadd/0448","http://hdl.handle.net/10442/hedi/0448"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["THIS WORK DEALS WITH THE STUDY OF SERUM AND URINE OF 76 CASES WITH B- NON HODGKIN'S LYMPHOMA, ACCORDING TO THE CRITERIA OF LUKES AND COLLINS, FOR THE DETECTION OF MONOCLONAL IMMUNOGLOBULINS. QUANTITATION OF SERUM IMMUNOGLOBULINS, DETECTION OF CRYOGLOBULINS AND INVESTIGATION OF THE MONOCLONAL IMMUNOGLOBULINS FOR AUTOANTIBODY SPECIFICITIES, WAS ALSO PERFORMED. THE OVERALL INCIDENCE OF MONOCLONAL IMMUNOGLOBULINS IN THESE PATIENTS WAS 25%. THE FREQUENCY OF THE DIFFERENT CATEGORIES OF B-NHL WAS AS FOLLOWS: CHRONIC LYMPHOMATIC LEUKAEMIA (CLL) 4%. FOLLICULAR CENTER CELL LYMPHOMAS (FCC) 11,7%, B-IMMUNOBLASTIC LYMPHOMA 40%, SMALL LYMPHOCYTIC LYMPHOMA (SLL) 41,6% AND PLASMACYTOID LYMPHOCYTIC LYMPHOMA 58,3%. HYPOGAMMAGLOBULINAEMIA WAS MORE FREQUENT IN CLL AND SLL. BENCE-JONES PROTEINS WAS FOUND IN 5 CASES. HIGH TITRE AUTOANTIBODIES WERE FOUND IN 4 PATIENTS WITH MONOCLONAL IMMUNOGLOBULINS.","ΣΤΗΝ ΕΡΓΑΣΙΑ ΑΥΤΗ ΜΕΛΕΤΗΘΗΚΑΝ ΟΡΟΣ ΚΑΙ ΟΥΡΑ 76 ΠΕΡΙΠΤΩΣΕΩΝ Β-ΜΝ HΟDGKIN'S ΛΕΜΦΩΜΑΤΩΝ ΤΑΞΙΝΟΜΗΜΕΝΩΝ ΜΕ ΤΑ ΚΡΙΤΗΡΙΑ ΤΩΝ LUKES ΚΑΙ COLLINS ΓΙΑ ΤΗΝ ΑΝΙΧΝΕΥΣΗ ΜΟΝΟΚΛΩΝΙΚΩΝ ΑΝΟΣΟΣΦΑIΡΙΝΩΝ. ΠΑΡΑΛΛΗΛΑ ΕΓΙΝΕ ΠΟΣΟΤΙΚΟΣ ΠΡΟΣΔΙΟΡΙΣΜΟΣ ΤΩΝ ΑΝΟΣΟΣΦΑΙΡΙΝΩΝ ΤΟΥ ΟΡΟΥ, ΑΝΙΧΝΕΥΣΗ ΚΡΥΟΣΦΑΙΡΙΝΩΝ ΚΑΙ ΕΛΕΓΧΟΣ ΓΙΑ ΠΑΡΟΥΣΙΑ ΑΥTΟΑΝΤΙΣΩΜΑΤΩΝ ΣΤΟΥΣ ΟΡΟΥΣ ΠΟΥ ΕΙΧΑΝ ΜΟΝΟΚΛΩΝΙΚΗ ΑΝΟΣΟΣΦΑΙΡΙΝΗ. Η ΣΥΧΝΟΤΗΤΑ ΤΩΝ ΜΟΝΟΚΛΩΝΙΚΩΝ ΑΝΟΣΟΣΦΑΙΡΙΝΩΝ ΗΤΑΝ 25%, ΜΕ ΤΗΝ ΕΞΗΣ ΣΕΙΡΑ ΣΤΟΥΣ ΔΙΑΦΟΡΟΥΣ ΤΥΠΟΥΣ ΛΕΜΦΩΜΑΤΩΝ: ΧΡΟΝΙΑ ΛΕΜΦΙΚΗ ΛΕΥΧΑΙΜΙΑ 4%, ΜΗΛ ΑΠΟ ΚΥΤΤΑΡΑ ΒΛΑΣΤΙΚΟΥ ΚΕΝΤΡΟΥ 11,7%, Β-ΑΝΟΣΟΒΛΑΣΤΙΚΟ ΛΕΜΦΩΜΑ 40%, ΜΗΛ ΑΠΟ ΜΙΚΡΑ ΛΕΜΦΟΚΥΤΤΑΡΑ 4,6%, ΜΗΛ ΑΠΟ ΠΛΑΣΜΑΤΟΚΥΤΤΑΡΟΕΙΔΗ ΛΕΜΦΟΚΥΤΤΑΡΑ 58,3%. Η ΥΠΟΓΑΜΜΑΣΦΑΙΡΙΝΑΙΜΙΑ ΗΤΑΝ ΠΙΟ ΣΥΧΝΗ ΣΤΗΝ ΧΛΛ ΚΑΙ ΣΤΟ ΛΕΜΦΩΜΑ ΑΠΟ ΜΙΚΡΑ ΛΕΜΦΟΚΥΤΤΑΡΑ. Η ΣΥΧΝΟΤΗΤΑ ΚΡYΟΣΦΑΙΡΙΝΩΝ ΣΤΟΥΣ ΟΡΟΥΣ ΜΕ ΜΟΝΟΚΛΩΝΙΚΗ ΑΝΟΣΟΣΦΑΙΡΙΝΗ ΗΤΑΝ 31,5%. Η ΣΥΧΝΟΤΗΤΑ ΠΡΩΤΕΙΝΟΥΡΙΑΣ BENCE-JONESΗΤΑΝ 29,4%. ΑΥΤΟΑΝΤΙΣΩΜΑΤΑ ΣΕ ΥΨΗΛΟΥΣ ΤΙΤΛΟΥΣ ΒΡΕΘΗΚΑΝ ΣΕ 4 ΑΠΟ 15 ΠΕΡΙΠΤΩΣΕΙΣ ΜΕ ΜΟΝΟΚΛΩΝΙΚΗ ΑΝΟΣΟΣΦΑΙΡΙΝΗ ΣΤΟΝ ΟΡΟ."]},{"key":"dc:title","label":"Title","values":["ΔΙΑΤΑΡΑΧΕΣ ΤΩΝ ΑΝΟΣΟΣΦΑΙΡΙΝΩΝ ΣΤΑ ΚΑΚΟΗΘΗ ΜΗ HODGKIN'S ΛΕΜΦΩΜΑΤΑ ΑΠΟ Β ΚΥΤΤΑΡΑ","IMMUNOGLOBULIN ABNORMALITIES IN B-NON HODGKIN'S LYMPHOMAS"]}]}],"canonical_facts":{"dc:creator":["Καρατσοπάνη-Τερζόγλου, Κωνσταντίνα"],"dc:date":["1986"],"dc:description":["THIS WORK DEALS WITH THE STUDY OF SERUM AND URINE OF 76 CASES WITH B- NON HODGKIN'S LYMPHOMA, ACCORDING TO THE CRITERIA OF LUKES AND COLLINS, FOR THE DETECTION OF MONOCLONAL IMMUNOGLOBULINS. QUANTITATION OF SERUM IMMUNOGLOBULINS, DETECTION OF CRYOGLOBULINS AND INVESTIGATION OF THE MONOCLONAL IMMUNOGLOBULINS FOR AUTOANTIBODY SPECIFICITIES, WAS ALSO PERFORMED. THE OVERALL INCIDENCE OF MONOCLONAL IMMUNOGLOBULINS IN THESE PATIENTS WAS 25%. THE FREQUENCY OF THE DIFFERENT CATEGORIES OF B-NHL WAS AS FOLLOWS: CHRONIC LYMPHOMATIC LEUKAEMIA (CLL) 4%. FOLLICULAR CENTER CELL LYMPHOMAS (FCC) 11,7%, B-IMMUNOBLASTIC LYMPHOMA 40%, SMALL LYMPHOCYTIC LYMPHOMA (SLL) 41,6% AND PLASMACYTOID LYMPHOCYTIC LYMPHOMA 58,3%. HYPOGAMMAGLOBULINAEMIA WAS MORE FREQUENT IN CLL AND SLL. BENCE-JONES PROTEINS WAS FOUND IN 5 CASES. HIGH TITRE AUTOANTIBODIES WERE FOUND IN 4 PATIENTS WITH MONOCLONAL IMMUNOGLOBULINS.","ΣΤΗΝ ΕΡΓΑΣΙΑ ΑΥΤΗ ΜΕΛΕΤΗΘΗΚΑΝ ΟΡΟΣ ΚΑΙ ΟΥΡΑ 76 ΠΕΡΙΠΤΩΣΕΩΝ Β-ΜΝ HΟDGKIN'S ΛΕΜΦΩΜΑΤΩΝ ΤΑΞΙΝΟΜΗΜΕΝΩΝ ΜΕ ΤΑ ΚΡΙΤΗΡΙΑ ΤΩΝ LUKES ΚΑΙ COLLINS ΓΙΑ ΤΗΝ ΑΝΙΧΝΕΥΣΗ ΜΟΝΟΚΛΩΝΙΚΩΝ ΑΝΟΣΟΣΦΑIΡΙΝΩΝ. ΠΑΡΑΛΛΗΛΑ ΕΓΙΝΕ ΠΟΣΟΤΙΚΟΣ ΠΡΟΣΔΙΟΡΙΣΜΟΣ ΤΩΝ ΑΝΟΣΟΣΦΑΙΡΙΝΩΝ ΤΟΥ ΟΡΟΥ, ΑΝΙΧΝΕΥΣΗ ΚΡΥΟΣΦΑΙΡΙΝΩΝ ΚΑΙ ΕΛΕΓΧΟΣ ΓΙΑ ΠΑΡΟΥΣΙΑ ΑΥTΟΑΝΤΙΣΩΜΑΤΩΝ ΣΤΟΥΣ ΟΡΟΥΣ ΠΟΥ ΕΙΧΑΝ ΜΟΝΟΚΛΩΝΙΚΗ ΑΝΟΣΟΣΦΑΙΡΙΝΗ. Η ΣΥΧΝΟΤΗΤΑ ΤΩΝ ΜΟΝΟΚΛΩΝΙΚΩΝ ΑΝΟΣΟΣΦΑΙΡΙΝΩΝ ΗΤΑΝ 25%, ΜΕ ΤΗΝ ΕΞΗΣ ΣΕΙΡΑ ΣΤΟΥΣ ΔΙΑΦΟΡΟΥΣ ΤΥΠΟΥΣ ΛΕΜΦΩΜΑΤΩΝ: ΧΡΟΝΙΑ ΛΕΜΦΙΚΗ ΛΕΥΧΑΙΜΙΑ 4%, ΜΗΛ ΑΠΟ ΚΥΤΤΑΡΑ ΒΛΑΣΤΙΚΟΥ ΚΕΝΤΡΟΥ 11,7%, Β-ΑΝΟΣΟΒΛΑΣΤΙΚΟ ΛΕΜΦΩΜΑ 40%, ΜΗΛ ΑΠΟ ΜΙΚΡΑ ΛΕΜΦΟΚΥΤΤΑΡΑ 4,6%, ΜΗΛ ΑΠΟ ΠΛΑΣΜΑΤΟΚΥΤΤΑΡΟΕΙΔΗ ΛΕΜΦΟΚΥΤΤΑΡΑ 58,3%. Η ΥΠΟΓΑΜΜΑΣΦΑΙΡΙΝΑΙΜΙΑ ΗΤΑΝ ΠΙΟ ΣΥΧΝΗ ΣΤΗΝ ΧΛΛ ΚΑΙ ΣΤΟ ΛΕΜΦΩΜΑ ΑΠΟ ΜΙΚΡΑ ΛΕΜΦΟΚΥΤΤΑΡΑ. Η ΣΥΧΝΟΤΗΤΑ ΚΡYΟΣΦΑΙΡΙΝΩΝ ΣΤΟΥΣ ΟΡΟΥΣ ΜΕ ΜΟΝΟΚΛΩΝΙΚΗ ΑΝΟΣΟΣΦΑΙΡΙΝΗ ΗΤΑΝ 31,5%. Η ΣΥΧΝΟΤΗΤΑ ΠΡΩΤΕΙΝΟΥΡΙΑΣ BENCE-JONESΗΤΑΝ 29,4%. ΑΥΤΟΑΝΤΙΣΩΜΑΤΑ ΣΕ ΥΨΗΛΟΥΣ ΤΙΤΛΟΥΣ ΒΡΕΘΗΚΑΝ ΣΕ 4 ΑΠΟ 15 ΠΕΡΙΠΤΩΣΕΙΣ ΜΕ ΜΟΝΟΚΛΩΝΙΚΗ ΑΝΟΣΟΣΦΑΙΡΙΝΗ ΣΤΟΝ ΟΡΟ."],"dc:identifier":["10.12681/eadd/0448","http://hdl.handle.net/10442/hedi/0448"],"dc:language":["gre"],"dc:publisher":["National and Kapodistrian University of Athens","Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)"],"dc:subject":["Ανοσοσφαιρίνες","Β-ΑΝΟΣΟΒΛΑΣΤΙΚΟ ΛΕΜΦΩΜΑ","Β-ΜΗ HODGKIN'S ΛΕΜΦΩΜΑΤΑ","ΛΕΜΦΩΜΑ ΑΠΟ ΚΥΤΤΑΡΑ ΤΟΥ ΒΛΑΣΤΙΚΟΥ ΚΕΝΤΡΟΥ","Λέμφωμα από μικρά λεμφοκύτταρα","ΛΕΜΦΩΜΑ ΑΠΟ ΠΛΑΣΜΑΤΟΚΥΤΤΑΡΟΕΙΔΗ ΛΕΜΦΟΚΥΤΤ ΥΠΟΓΑΜΜΑΣΦΑΙΡΙΝΑΙΜΙΑ","Μονοκλωνικές ανοσοσφαιρίνες","Λευχαιμία, Χρόνια λεμφική","B-IMMUNOBLASTIC LYMPHOMA","B - non Hodgkin's lymphomas","Chronic lymphocytic leukemia","FOLLICULAR CENTER CELL LYMPHOMA","HYPOGAMMAGLOBULINAEMIA","Immunoglobulins","Monoclonal immunoglobulins","PLASMACYTOID LYMPHOCYTIC LYMPHOMA","Small lymphocytic lymphoma","Ιατρική και Επιστήμες Υγείας","Κλινική Ιατρική","Medical and Health Sciences","Clinical Medicine"],"dc:title":["ΔΙΑΤΑΡΑΧΕΣ ΤΩΝ ΑΝΟΣΟΣΦΑΙΡΙΝΩΝ ΣΤΑ ΚΑΚΟΗΘΗ ΜΗ HODGKIN'S ΛΕΜΦΩΜΑΤΑ ΑΠΟ Β ΚΥΤΤΑΡΑ","IMMUNOGLOBULIN ABNORMALITIES IN B-NON HODGKIN'S LYMPHOMAS"],"dc:type":["PhD Thesis"]},"updated_at":"2026-07-24T02:25:17Z"}