ΣΥΣΧΕΤΙΣΕΙΣ ΤΙΜΩΝ ΑΙΜΟΣΦΑΙΡΙΝΗΣ Α1(HBA1) ΚΑΙ ΠΟΛΛΑΠΛΩΝ ΠΡΟΣΔΙΟΡΙΣΜΩΝ ΓΛΥΚΟΖΗΣ ΑΙΜΑΤΟΣ ΝΗΣΤΕΙΑΣ ΕΠΙ ΣΑΚΧΑΡΩΔΟΥΣ ΔΙΑΒΗΤΟΥ ΟΨΙΜΟΥ ΕΝΑΡΞΕΩΣ

DETERMINATION OF HAEMOGLOBIN A1 (HBA1) BY CATION EXCHANGE RESIN METHOD USING MICROCOLUMN WAS CARRIED OUT IN 107 MATURITY ONSET DIABETICS ATTENDING THE OUT PATIENT DIABETIC CLINIC OF EVANGELISMOS HOSPITAL. THE PATIENTS ACCORDING TO THEIR TREATMENT WERE DIVIDED IN THREE GROUPS: GROUP A UNDER INSULIN (24 PATIENTS), GROUP B ON ORAL TREATMENT (67 PATIENTS) AND GROUP C (18 PATIENTS) ON DIET ONLY. IN THESE PATIENTS THE HBA1 VALUE WAS CORRELATED TO SERIAL FASTING BLOOD GLUCOSE (FBS) VALUES DURING THE PREVIOUS AND FOLLOWING THE HBA1 DETERMINATION, 5 MONTH PERIOD. IT WAS FOUND THAT: A) IN GROUP A THERE WAS ONLY A POSSIBILITY SIGNIFICANT CORRELATION (P < 0,05) BETWEEN THE HBA1 AND THE FBS OF THE SAME DAY OR 4 WEEKS PREVIOUSLY, B) IN GROUP B THERE WAS A HIGHLY SIGNIFICANT CORRELATION (P < 0,001) BETWEEN THE HBA1 AND THE FBS OF THE SAME DAY AND 4, 8 AND 12 WEEKS PREVIOUSLY AS WELL AS THE MEAN FBS OF THE PREVIOUSLY AND FOLLOWING 3 MONTHS, C) IN GROUP C THE CORRELATION WAS SIGNIFICANT (P < 0,01) BETWEEN THE HBA1 AND THE FBS OF THE SAME DAY OR THE MEAN OF THE PREVIOUSLY 3 MONTHS. FURTHER ANALYSIS OF THE RESULTS SHOWED THAT FOR HBA1 VALUES DEFINITELY ABNORMAL A VERY SMALL PROPORTION OF THE PATIENTS HAD FBS VALUES LOWER THAN 160 MG/DL WHILE THEOPPOSITE WAS NOT ALWAYS VALID. FROM THE ABOVE IT IS CONCLUDED THAT ONE HBA1 VALUE IS A VALUABLE INDEX OF THE PATIENTS WITH STABLE. ANOTHER CONCLUSION IS THAT HBA1 VALUES DEFINITELY ABNORMAL (HIGHER THAN 10% FOR THESE PATIENTS) REFLECT UNSATISFACTORY CONTROL OF THE DIABETES AT LEAST AS THIS CAN BE JUDGED BY THEDETERMINATION OF FASTING BLOOD GLUCOSE.

Grantor dc:publisher

National and Kapodistrian University of Athens

Year dc:date

1986

Authors dc:creator

• Kleanthous, Ioannis
• Κλεάνθους, Ιωάννης

• Diabetes mellitus
• Glycosylated haemoglobin {HBA1}
• Γλυκοζυλιωνένη αιμοσφαιρίνη {HBA1}
• Σακχαρώδης διαβήτης
• Ιατρική και Επιστήμες Υγείας
• Βασική Ιατρική
• Κλινική Ιατρική
• Medical and Health Sciences
• Basic Medicine
• Clinical Medicine

Language dc:language

gre

Identifier

10.12681/eadd/0428

OAI identifier oai:identifier

oai:10442/0428