ΜΕΛΕΤΗ ΤΗΣ ΣΥΓΚΕΝΤΡΩΣΕΩΣ ΝΕΩΤΕΡΩΝ ΑΝΤΙΜΙΚΡΟΒΙΑΚΩΝ ΦΑΡΜΑΚΩΝ ΣΤΟ ΕΓΚΕΦΑΛΟΝΩΤΙΑΙΟ ΥΓΡΟ

THE CONCENTRATION OF SIX CEPHALOSPORINS AFTER SINGLE OR REPEATED DOSAGE WAS STUDIED IN NORMAL C.S.F. OF 74 PATIENTS. THE ONLY CEPHALOSPORINE GIVING CONSISTENTLY MEASURABLE LEVELS IN C.S.F. IN ALL TEN PATIENTS TO WHOM IT WAS GIVEN WAS CEFTOZIDIME. ALSO THERE WERE DETECTABLE LEVELS OF CEFUROXIME AND CEPHALORIDINE. THESE WERE NO DETECTABLE LEVELS NEITHER OF CEPHOPERAZONE NOR OF CEFSULODINE AND CEFOTAXIME. ON THE BASIS OF THE ABOVE FINDINGS AND THE M.I.C. OF THE CEPHALOSPORINS WE RECOMMED CEFTAZIDIME AS THE CEPHALOSPORINE OF CHOISE IN GRAM NEGATIVE MENINGITIS INCLUDING THAT DUE TO PSEUDOMONAS, ESPECIALLY UNDER CONDITIONS WHERE CONCENTRATIONS OF THE ANTIBIOTIC IN NORMAL C.S.F. IS IMPORTANT.

Grantor dc:publisher

National and Kapodistrian University of Athens

Year dc:date

1986

Author dc:creator

• Πουριέζη-Λευκίδη, Θεοδώρα

• CEFOPERAZONE
• CEFORAXIME
• CEFSULODINE
• Ceftazidime
• Cefuroxime
• CEPHALORIDIN
• Cephalosporins
• Cerebrospinal fluid
• Εγκεφαλονωτιαίο υγρό
• Κεφαλοριδίνη
• Κεφαλοσπορίνες
• ΚΕΦΟΠΕΡΑΖΟΝΗ
• Κεφοταξίμη
• Κεφουροξίμη
• ΚΕΦΣΟΥΛΟΔΙΝΗ
• Κεφταζιδίμη
• Ιατρική και Επιστήμες Υγείας
• Βασική Ιατρική
• Medical and Health Sciences
• Basic Medicine

Language dc:language

gre

Identifier

10.12681/eadd/0424

OAI identifier oai:identifier

oai:10442/0424