ΑΠΟΤΕΛΕΣΜΑΤΑ ΚΑΙ ΙΣΤΟΛΟΓΙΚΕΣ ΑΛΛΟΙΩΣΕΙΣ ΤΩΝ ΟΓΚΩΝ ΜΕΤΑ ΑΠΟ ΕΝΔΟΚΥΣΤΙΚΕΣ ΕΓΧΥΣΕΙΣ

THE EFFECTIVENESS AND THE RESULTS OF INTRAVESICAL INFUSIONS OF CYTOTOXIC AGENTS ON PATIENTS WITH SUPERFICIAL SLADDER TUMOUR ARE PRESENTED. THE EFFECTIVENESSHAVE BEEN CONFIRMED BY THE ESTIMATION OF THE RESULTS OF INTRAVESICAL INSTALLATION OF ADNAMYHCIN IN 36 PATIENTS WITH T0 AND 8 T1. EPODYL IN 6 PATIENTS WITH T0 AND 4 T1 AND BY INSTALLATIONS OF THIOTEPA IN 4 PATIENTS WITH T0 AND 3 PATIENTS WITH T1. THE RESULTS SHOW THAT THE THREE CYTOTOXIC AGENT WORK ON SLADDER TUMOUR WITH THE SAME SUCCESS. THE SIDE EFFECTS OF ALL CYTOTOXIC DRUGS WERE UNSIGNIFICANT AND WE CAN SAY THAT THE INSTALLATION SHOULD BE DONE ON ALL KINDS OFPATIENTS. THE HISTOPATHOLOGICAL CHANGES UNDER ELECTRON MICROSCOPE CAN BE CLASSIFIED INTO FIVE DEGREES OF A) APPEARANCE OF NUMEROUS CYTOPLASMIC VACUOLI, B) DAMAGED TUMOUR CELLS AND RESERED OF TUMOUR CELL NEST. C) DAMAGES TUMOUR DEEP CELL AND TUMOUR NEST. D) CHANGES IN CAPILLARY ENDOTHELIUM. E) APPEARANCE OF HIDROTIC TISSUE. THOSE CHANGES DEPEND ON THE NUMBER OF THE INSTALLATION AND TUMOUR GRADE. SIMILAR CHANGES WERE SEEN IN NORMAL BLADDER MUCOSSA BUT WERE LESS SEVERE AND AFTER NUMEROUS INSTALLATIONS.

Grantor dc:publisher

National and Kapodistrian University of Athens

Year dc:date

1982

Author dc:creator

• Μπίσας, Απόστολος

• Ενδοκυστικές εκχύσεις
• ΜΗ-ΔΙΗΘΗΤΙΚΟΙ ΟΓΚΟΙ ΟΥΡΟΔΟΧΟΥ ΚΥΣΤΕΩΣ
• ΠΑΘΟΛΟΓΙΚΕΣ ΑΛΛΟΙΩΣΕΙΣ
• Intravesical instillations
• PATHOLOGICAL CHANGES
• SUPERFICIAL TRANSITIONAL CELL CARCINOMA
• Ιατρική και Επιστήμες Υγείας
• Κλινική Ιατρική
• Medical and Health Sciences
• Clinical Medicine

Language dc:language

gre

Identifier

10.12681/eadd/0384

OAI identifier oai:identifier

oai:10442/0384