Η ΡΕΥΜΑΤΟΕΙΔΗΣ ΑΡΘΡΙΤΙΔΑ ΣΤΗΝ ΕΛΛΑΔΑ. ΚΛΙΝΙΚΗ, ΟΡΟΛΟΓΙΚΗ ΚΑΙ ΑΝΟΣΟΓΕΝΕΤΙΚΗ ΜΕΛΕΤΗ

THE CLINICAL PICTURE, AS WELL AS RADIOLOGIC, SEROLOGIC AND HISTOLOGIC MANIFESTATIONS WERE STUDIED IN 105 GREEK PATIENTS WITH CLASSICAL OR DEFINITE RHEUMATOID ARTHRITIS. ARTICULAR MANIFESTATIONS IN GREEK R.A PATIENTS ARE SIMILAR TO THESE DESCRIBED IN THE INTERNATIONAL LITERATURE WHILE RHEUMATOID MODULES, CUTANEOUS VASCULITIS AND FELTY'S SYNDROME SEEM TO BE MORE UNFREQUENT. IN CONTRAST, ANTIBODIES TO RO(SSA) CELLULAR ANTIGEN ARE FOUND MORE FREQUENTLY (14%) THAN DESCRIBED PREVIOUSLY IN THE LITERATURE. FINALLY, R.A IN GREEK PATIENTS IS NOT ASSOCIATED WITH HLA-DR4. COMPARING THE CLINICAL, LABORATORY, HISTOLOGIC AND RADIOLOGIC MANIFESTATIONS OF ANTI-RO(SSA) POSITIVE TO ANTI-RO(SSA) NEGATIVE R.A PATIENTS, IT WAS OBSERVED THAT ANTI-RO(SSA) POSITIVE R.A PATIENTS PRESENT WITH THE SAME ARTICULAR AND EXTRAARTICULAR MANIFESTATIONS. HOWEVER, THEY ARE PREDOMINANTLY FEMALES WITH LOWER RHEUMATOID FACTOR TITERS AND HIGH INCIDENCE OF POSITIVE MINOR SALIVARY GLAND BIOPSIES FOR SJOGREN'S SYNDROME. IT WAS ALSO FOUND THAT ANTI- RO(SSA) POSITIVE R.A PATIENTS FREQUENTLY EXPRESS PENICILLAMINE SIDE- EFFECTS. FINALLY, AN INCREASED PREVELANCE, BUT NOT STATISTICALLY SIGNIFICANT, OFTHE HLA-DRS ANTIGEN WAS OBSERVED IN THE RO(SSA) POSITIVE R.A GROUP.

Grantor dc:publisher

University of Ioannina

Year dc:date

1986

Author dc:creator

• Σκοπούλη, Φωτεινή

• Αντι-Ro-SSA αντίσωμα
• Αντιγόνα ιστοσυμβατότητας HLA
• ΑΝΤΙΣΩΜΑΤΑ ΣΕ ΑΝΤΙΓΟΝΑ ΕΚΧΥΛΙΣΜΑΤΩΝ ΚΥΤΤΑΡΟΥ
• Δ-ΠΕΝΙΚΙΛΛΑΜΙΝΗ
• Παθολογία
• Ρευματοειδής αρθρίτιδα
• ANTIBODIES TO EXTRACTABLE NUCLEAR ANTIGENS
• ANTIBODY TO RO-SSA
• D-penicillamine
• HLA HISTOCOMPATIBILITY ANTIGENS
• Rheumatoid arthritis
• Ιατρική και Επιστήμες Υγείας
• Επιστήμες Υγείας
• Κλινική Ιατρική
• Medical and Health Sciences
• Health Sciences
• Clinical Medicine

Language dc:language

gre

Identifier

10.12681/eadd/0104

OAI identifier oai:identifier

oai:10442/0104