Ongoing efforts to incorporate traditional or herbal medicine practice into the main stream healthcare delivery system of Ghana has led to increased research to isolate, identify, and characterize the active ingredients in these herbal products. It has also led to the development of semi-synthetic drugs and pharmacologically-active compounds. Essential oils from different parts of Xylopia aethiopica, a plant of Africa, showed various degrees of anti bacterial activity. The activity has been attributed to the presence of Xylopic acid the major diterpene component of the fruit oil extract. This work examines the effects of extraction solvent and time of extraction on the yield of xylopic acid. Xylopic acid was isolated from the dried fruits of Xylopia aethiopica using petroleum ether and characterized using various analytical tools. This was then used as reference standard to design an HPLC method to quantify the amount of the acid extracted using different solvent systems.
","abstract_html":"<p>Ongoing efforts to incorporate traditional or herbal medicine practice into the main stream healthcare delivery system of Ghana has led to increased research to isolate, identify, and characterize the active ingredients in these herbal products. It has also led to the development of semi-synthetic drugs and pharmacologically-active compounds. Essential oils from different parts of <em>Xylopia aethiopica,</em> a plant of Africa, showed various degrees of anti bacterial activity. The activity has been attributed to the presence of Xylopic acid the major diterpene component of the fruit oil extract. This work examines the effects of extraction solvent and time of extraction on the yield of xylopic acid. Xylopic acid was isolated from the dried fruits of<em> Xylopia aethiopica</em> using petroleum ether and characterized using various analytical tools. This was then used as reference standard to design an HPLC method to quantify the amount of the acid extracted using different solvent systems.</p>","abstract_has_math":false,"creators":["Esuon, Francis"],"institution":null,"degree_name":"MS (Master of Science)","degree_level":"Thesis - restricted","degree_discipline":"Chemistry","degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2013,"date_issued":"2013-05-01T07:00:00Z","date_published":"2013-05-01T07:00:00Z","updated_at":"2026-07-24T02:19:59Z","subjects":["xylopic acid","Xylopia aethiopica","Chemistry"],"languages":[],"rights":["Copyright by the authors."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://dc.etsu.edu/etd/1171","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Esuon, Francis"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2013-04-08T07:00:00Z"]},{"key":"dc:date.issued","label":"Date","values":["2013-05-01T07:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Chemistry"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis - restricted"]},{"key":"thesis:degree_name","label":"Degree Name","values":["MS (Master of Science)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["xylopic acid","Xylopia aethiopica","Chemistry"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:rights","label":"Dc Rights","values":["Copyright by the authors."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://dc.etsu.edu/context/etd/article/2340/viewcontent/EsuonF050913f.pdf","https://dc.etsu.edu/etd/1171"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Ongoing efforts to incorporate traditional or herbal medicine practice into the main stream healthcare delivery system of Ghana has led to increased research to isolate, identify, and characterize the active ingredients in these herbal products. It has also led to the development of semi-synthetic drugs and pharmacologically-active compounds. Essential oils from different parts of Xylopia aethiopica, a plant of Africa, showed various degrees of anti bacterial activity. The activity has been attributed to the presence of Xylopic acid the major diterpene component of the fruit oil extract. This work examines the effects of extraction solvent and time of extraction on the yield of xylopic acid. Xylopic acid was isolated from the dried fruits of Xylopia aethiopica using petroleum ether and characterized using various analytical tools. This was then used as reference standard to design an HPLC method to quantify the amount of the acid extracted using different solvent systems.
"]},{"key":"dc:title","label":"Title","values":["Extraction and Characterization of Xylopic Acid from Xylopia aethiopica"]}]}],"canonical_facts":{"dc:creator":["Esuon, Francis"],"dc:date.available":["2013-04-08T07:00:00Z"],"dc:date.issued":["2013-05-01T07:00:00Z"],"dc:description.abstract":["Ongoing efforts to incorporate traditional or herbal medicine practice into the main stream healthcare delivery system of Ghana has led to increased research to isolate, identify, and characterize the active ingredients in these herbal products. It has also led to the development of semi-synthetic drugs and pharmacologically-active compounds. Essential oils from different parts of Xylopia aethiopica, a plant of Africa, showed various degrees of anti bacterial activity. The activity has been attributed to the presence of Xylopic acid the major diterpene component of the fruit oil extract. This work examines the effects of extraction solvent and time of extraction on the yield of xylopic acid. Xylopic acid was isolated from the dried fruits of Xylopia aethiopica using petroleum ether and characterized using various analytical tools. This was then used as reference standard to design an HPLC method to quantify the amount of the acid extracted using different solvent systems.
"],"dc:identifier":["https://dc.etsu.edu/context/etd/article/2340/viewcontent/EsuonF050913f.pdf","https://dc.etsu.edu/etd/1171"],"dc:rights":["Copyright by the authors."],"dc:subject":["xylopic acid","Xylopia aethiopica","Chemistry"],"dc:title":["Extraction and Characterization of Xylopic Acid from Xylopia aethiopica"],"thesis:degree_discipline":["Chemistry"],"thesis:degree_level":["Thesis - restricted"],"thesis:degree_name":["MS (Master of Science)"]},"updated_at":"2026-07-24T02:19:59Z"}