Hydroxychloroquine is a highly effective and commonly used disease-modifying anti-rheumatic drug (DMRD) for the treatment of various autoimmune diseases. Recently this medication received lot of attention in the medical world as a potential treatment for COVID-19. The goal of this research is to perform a systematic review of literature to focus on the efficacy of hydroxychloroquine in COVID-19 patients and any evidence of adverse reactions. The database used to conduct this research was PubMed, using four keywords and phrases: effects, side effects, adverse events, and serious adverse events of hydroxychloroquine in COVID-19 patients. Out of the 15 articles selected for the final review, 12 articles indicated no clinical improvement and 10 articles did not indicate any evidence of adverse reactions. The conclusion of the research is that hydroxychloroquine indicates lack of efficacy as treatment in patients with COVID-19, and there is not enough conclusive evidence for adverse reactions.
","abstract_html":"<p>Hydroxychloroquine is a highly effective and commonly used disease-modifying anti-rheumatic drug (DMRD) for the treatment of various autoimmune diseases. Recently this medication received lot of attention in the medical world as a potential treatment for COVID-19. The goal of this research is to perform a systematic review of literature to focus on the efficacy of hydroxychloroquine in COVID-19 patients and any evidence of adverse reactions. The database used to conduct this research was PubMed, using four keywords and phrases: effects, side effects, adverse events, and serious adverse events of hydroxychloroquine in COVID-19 patients. Out of the 15 articles selected for the final review, 12 articles indicated no clinical improvement and 10 articles did not indicate any evidence of adverse reactions. The conclusion of the research is that hydroxychloroquine indicates lack of efficacy as treatment in patients with COVID-19, and there is not enough conclusive evidence for adverse reactions.</p>","abstract_has_math":false,"creators":["Joseph, Soumy Maria"],"institution":null,"degree_name":"Master of Science (MS)","degree_level":"Open Access Thesis","degree_discipline":"Health Sciences","degree_department":null,"school":null,"contributors":["Michael Switzer, Ph.D.","Jean Rowan, MD, MS"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2021,"date_issued":"2021-01-01T08:00:00Z","date_published":"2021-01-01T08:00:00Z","updated_at":"2026-07-24T02:17:40Z","subjects":["Adverse Events","COVID-19 Patients","Effects","Hydroxychloroquine","Serious Adverse Events","Side Effects","Medicine and Health Sciences"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://commons.emich.edu/theses/1107","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Michael Switzer, Ph.D.","Jean Rowan, MD, MS"]},{"key":"dc:creator","label":"Author","values":["Joseph, Soumy Maria"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2022-02-01T08:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Health Sciences"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Open Access Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science (MS)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Adverse Events","COVID-19 Patients","Effects","Hydroxychloroquine","Serious Adverse Events","Side Effects","Medicine and Health Sciences"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://commons.emich.edu/theses/1107"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Hydroxychloroquine is a highly effective and commonly used disease-modifying anti-rheumatic drug (DMRD) for the treatment of various autoimmune diseases. Recently this medication received lot of attention in the medical world as a potential treatment for COVID-19. The goal of this research is to perform a systematic review of literature to focus on the efficacy of hydroxychloroquine in COVID-19 patients and any evidence of adverse reactions. The database used to conduct this research was PubMed, using four keywords and phrases: effects, side effects, adverse events, and serious adverse events of hydroxychloroquine in COVID-19 patients. Out of the 15 articles selected for the final review, 12 articles indicated no clinical improvement and 10 articles did not indicate any evidence of adverse reactions. The conclusion of the research is that hydroxychloroquine indicates lack of efficacy as treatment in patients with COVID-19, and there is not enough conclusive evidence for adverse reactions.
"]},{"key":"dc:title","label":"Title","values":["A systematic review of the efficacy of hydroxychloroquine in COVID-19 patients"]}]}],"canonical_facts":{"dc:contributor":["Michael Switzer, Ph.D.","Jean Rowan, MD, MS"],"dc:creator":["Joseph, Soumy Maria"],"dc:date.available":["2022-02-01T08:00:00Z"],"dc:description.abstract":["Hydroxychloroquine is a highly effective and commonly used disease-modifying anti-rheumatic drug (DMRD) for the treatment of various autoimmune diseases. Recently this medication received lot of attention in the medical world as a potential treatment for COVID-19. The goal of this research is to perform a systematic review of literature to focus on the efficacy of hydroxychloroquine in COVID-19 patients and any evidence of adverse reactions. The database used to conduct this research was PubMed, using four keywords and phrases: effects, side effects, adverse events, and serious adverse events of hydroxychloroquine in COVID-19 patients. Out of the 15 articles selected for the final review, 12 articles indicated no clinical improvement and 10 articles did not indicate any evidence of adverse reactions. The conclusion of the research is that hydroxychloroquine indicates lack of efficacy as treatment in patients with COVID-19, and there is not enough conclusive evidence for adverse reactions.
"],"dc:identifier":["https://commons.emich.edu/theses/1107"],"dc:subject":["Adverse Events","COVID-19 Patients","Effects","Hydroxychloroquine","Serious Adverse Events","Side Effects","Medicine and Health Sciences"],"dc:title":["A systematic review of the efficacy of hydroxychloroquine in COVID-19 patients"],"thesis:degree_discipline":["Health Sciences"],"thesis:degree_level":["Open Access Thesis"],"thesis:degree_name":["Master of Science (MS)"]},"updated_at":"2026-07-24T02:17:40Z"}