Catalysts are reagents used to reduce the amount of energy that a reaction needs to execute, allowing it to proceed at a higher rate while not being consumed. The use of catalyst functionalized amphiphilic copolymer allows easier recovery of the catalyst at the end of the synthesis and allows for the reaction. In water, under appropriate conditions, the amphiphilic block copolymers will form micelles and allow the reaction to occur on the interior of the micelle. The synthesis of amphiphilic copolymer with a hydrophobic O-methacryloyl-trans-4- hydroxy-L-proline and methyl methacrylate end and a hydrophilic acrylic acid end was characterized. The polymer was tested as an asymmetric catalyst for an aldol reaction in aqueous conditions. The polymer was able to successfully stereoselectively catalyze the reaction with a preference for the anti-addition.
","abstract_html":"<p>Catalysts are reagents used to reduce the amount of energy that a reaction needs to execute, allowing it to proceed at a higher rate while not being consumed. The use of catalyst functionalized amphiphilic copolymer allows easier recovery of the catalyst at the end of the synthesis and allows for the reaction. In water, under appropriate conditions, the amphiphilic block copolymers will form micelles and allow the reaction to occur on the interior of the micelle. The synthesis of amphiphilic copolymer with a hydrophobic O-methacryloyl-trans-4- hydroxy-L-proline and methyl methacrylate end and a hydrophilic acrylic acid end was characterized. The polymer was tested as an asymmetric catalyst for an aldol reaction in aqueous conditions. The polymer was able to successfully stereoselectively catalyze the reaction with a preference for the anti-addition.</p>","abstract_has_math":false,"creators":["Firestone, Eric"],"institution":null,"degree_name":"Master of Science (MS)","degree_level":"Open Access Thesis","degree_discipline":"Chemistry","degree_department":null,"school":null,"contributors":["Gregg Wilmes, PhD,","Cory Emal, PhD","Timothy Friebe, PhD"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2018,"date_issued":"2018-01-01T08:00:00Z","date_published":"2018-01-01T08:00:00Z","updated_at":"2026-07-24T02:17:27Z","subjects":["Block Copolymer","Micelle","Proline","RAFT Polymerization","Chemistry","Organic Chemistry","Polymer Chemistry"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://commons.emich.edu/theses/920","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Gregg Wilmes, PhD,","Cory Emal, PhD","Timothy Friebe, PhD"]},{"key":"dc:creator","label":"Author","values":["Firestone, Eric"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2018-10-03T07:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Chemistry"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Open Access Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science (MS)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Block Copolymer","Micelle","Proline","RAFT Polymerization","Chemistry","Organic Chemistry","Polymer Chemistry"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://commons.emich.edu/theses/920"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Catalysts are reagents used to reduce the amount of energy that a reaction needs to execute, allowing it to proceed at a higher rate while not being consumed. The use of catalyst functionalized amphiphilic copolymer allows easier recovery of the catalyst at the end of the synthesis and allows for the reaction. In water, under appropriate conditions, the amphiphilic block copolymers will form micelles and allow the reaction to occur on the interior of the micelle. The synthesis of amphiphilic copolymer with a hydrophobic O-methacryloyl-trans-4- hydroxy-L-proline and methyl methacrylate end and a hydrophilic acrylic acid end was characterized. The polymer was tested as an asymmetric catalyst for an aldol reaction in aqueous conditions. The polymer was able to successfully stereoselectively catalyze the reaction with a preference for the anti-addition.
"]},{"key":"dc:title","label":"Title","values":["Synthesis and catalytic testing of a proline functionalized amphiphilic block copolymer"]}]}],"canonical_facts":{"dc:contributor":["Gregg Wilmes, PhD,","Cory Emal, PhD","Timothy Friebe, PhD"],"dc:creator":["Firestone, Eric"],"dc:date.available":["2018-10-03T07:00:00Z"],"dc:description.abstract":["Catalysts are reagents used to reduce the amount of energy that a reaction needs to execute, allowing it to proceed at a higher rate while not being consumed. The use of catalyst functionalized amphiphilic copolymer allows easier recovery of the catalyst at the end of the synthesis and allows for the reaction. In water, under appropriate conditions, the amphiphilic block copolymers will form micelles and allow the reaction to occur on the interior of the micelle. The synthesis of amphiphilic copolymer with a hydrophobic O-methacryloyl-trans-4- hydroxy-L-proline and methyl methacrylate end and a hydrophilic acrylic acid end was characterized. The polymer was tested as an asymmetric catalyst for an aldol reaction in aqueous conditions. The polymer was able to successfully stereoselectively catalyze the reaction with a preference for the anti-addition.
"],"dc:identifier":["https://commons.emich.edu/theses/920"],"dc:subject":["Block Copolymer","Micelle","Proline","RAFT Polymerization","Chemistry","Organic Chemistry","Polymer Chemistry"],"dc:title":["Synthesis and catalytic testing of a proline functionalized amphiphilic block copolymer"],"thesis:degree_discipline":["Chemistry"],"thesis:degree_level":["Open Access Thesis"],"thesis:degree_name":["Master of Science (MS)"]},"updated_at":"2026-07-24T02:17:27Z"}