Retrotransposons are a type of transposable element in which DNA copies are produced via an RNA intermediate and integrate into new chromosomal sites continually contributing to the dynamics of genomes. While sequencing the mys element among the Cricetidae family of rodents, we identified a previously uncharacterized element in the genome of the Mexican volcano mouse that we refer to as mys-related sequence (mysRS). This investigation provides a unique opportunity to contrast the evolution of the two retrotransposon families apparently restricted to a specific taxonomic group of rodents. By analyzing the genomes of various cricetid rodents, our results provide evidence that the mysRS element originated in either an ancestor of the Neotominae subfamily or the Reithrodontomini tribe of rodents, which diverged roughly nine million years ago, and predates the appearance of the mys element.
","abstract_html":"<p>Retrotransposons are a type of transposable element in which DNA copies are produced via an RNA intermediate and integrate into new chromosomal sites continually contributing to the dynamics of genomes. While sequencing the mys element among the Cricetidae family of rodents, we identified a previously uncharacterized element in the genome of the Mexican volcano mouse that we refer to as mys-related sequence (mysRS). This investigation provides a unique opportunity to contrast the evolution of the two retrotransposon families apparently restricted to a specific taxonomic group of rodents. By analyzing the genomes of various cricetid rodents, our results provide evidence that the mysRS element originated in either an ancestor of the Neotominae subfamily or the Reithrodontomini tribe of rodents, which diverged roughly nine million years ago, and predates the appearance of the mys element.</p>","abstract_has_math":false,"creators":["Scott, Megan M"],"institution":null,"degree_name":"Master of Science (MS)","degree_level":"Open Access Thesis","degree_discipline":"Biology","degree_department":null,"school":null,"contributors":["David Kass","Katherine Greenwald","Lynne Shetron-Rama"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2016,"date_issued":"2016-01-01T08:00:00Z","date_published":"2016-01-01T08:00:00Z","updated_at":"2026-07-24T02:17:13Z","subjects":["Cricetidae","mys","mysRS","Retrotransposons","Biology","Life Sciences"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://commons.emich.edu/theses/786","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["David Kass","Katherine Greenwald","Lynne Shetron-Rama"]},{"key":"dc:creator","label":"Author","values":["Scott, Megan M"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2018-03-07T08:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Biology"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Open Access Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science (MS)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Cricetidae","mys","mysRS","Retrotransposons","Biology","Life Sciences"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://commons.emich.edu/theses/786"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Retrotransposons are a type of transposable element in which DNA copies are produced via an RNA intermediate and integrate into new chromosomal sites continually contributing to the dynamics of genomes. While sequencing the mys element among the Cricetidae family of rodents, we identified a previously uncharacterized element in the genome of the Mexican volcano mouse that we refer to as mys-related sequence (mysRS). This investigation provides a unique opportunity to contrast the evolution of the two retrotransposon families apparently restricted to a specific taxonomic group of rodents. By analyzing the genomes of various cricetid rodents, our results provide evidence that the mysRS element originated in either an ancestor of the Neotominae subfamily or the Reithrodontomini tribe of rodents, which diverged roughly nine million years ago, and predates the appearance of the mys element.
"]},{"key":"dc:title","label":"Title","values":["Evolution of the mysRS element in the genome of rodent species"]}]}],"canonical_facts":{"dc:contributor":["David Kass","Katherine Greenwald","Lynne Shetron-Rama"],"dc:creator":["Scott, Megan M"],"dc:date.available":["2018-03-07T08:00:00Z"],"dc:description.abstract":["Retrotransposons are a type of transposable element in which DNA copies are produced via an RNA intermediate and integrate into new chromosomal sites continually contributing to the dynamics of genomes. While sequencing the mys element among the Cricetidae family of rodents, we identified a previously uncharacterized element in the genome of the Mexican volcano mouse that we refer to as mys-related sequence (mysRS). This investigation provides a unique opportunity to contrast the evolution of the two retrotransposon families apparently restricted to a specific taxonomic group of rodents. By analyzing the genomes of various cricetid rodents, our results provide evidence that the mysRS element originated in either an ancestor of the Neotominae subfamily or the Reithrodontomini tribe of rodents, which diverged roughly nine million years ago, and predates the appearance of the mys element.
"],"dc:identifier":["https://commons.emich.edu/theses/786"],"dc:subject":["Cricetidae","mys","mysRS","Retrotransposons","Biology","Life Sciences"],"dc:title":["Evolution of the mysRS element in the genome of rodent species"],"thesis:degree_discipline":["Biology"],"thesis:degree_level":["Open Access Thesis"],"thesis:degree_name":["Master of Science (MS)"]},"updated_at":"2026-07-24T02:17:13Z"}