Clinical studies of breathing during sleep and sudden infant death syndrome

The primary aim of the research reported in this thesis was to study breathing patterns during sleep in a) apparently normal symptom-free full-term infants, b) infants admitted to hospital during and following recovery from relatively minor illnesses, and c] infants thought to be at increased risk for Sudden Infant Death Syndrome CSIDS) - siblings of previous SIDS victims, and 'near-miss' for SIDS cases, to quantify apnoea (central and obstructive] and observe its effect on heart rate and transcutaneous oxygen tension, PtcO₂. Secondary aims were to study gross body movements (as an indicator of arousal], and to assess whether infants at 'increased risk' for SIDS were chronicallyhypoxaemic during the early months of life. Polysomniographic studies lasting three to five hours during the night recorded eye movements, digastric muscle tone, electrocardiogram^, electroencephalogram, airflow, chest and abdominal movements and PtcO₂ in 86 index cases and 11 healthy controls studied on 176 and 31 occasions respectively.

Grantor dc:publisher

The University of Edinburgh

Year dc:date.issued

1985

Author dc:creator

• Abreu e Silva, Fernando Antonio.

Handle dc:identifier.uri

http://hdl.handle.net/1842/30126

OAI identifier oai:identifier

oai:era.ed.ac.uk:1842/30126