Some investigations to compare the durability and performance of mechanical and porcine heart valve prostheses

The work reported in this thesis is an inherent part of research carried out in Edinburgh to assess the performance and durability of heart valve prostheses. Frcm 1975 to 1979 540 patients undergoing heart valve replacement in Edinburgh Royal Infirmary were entered into a randomised trial and received either a mechanical (Bjork-Shiley), or porcine heterograft (Hancock or Carpentier-Edwards) prosthesis. Starting in 1977 in the United States the Veterans Administration carried out a similar randomised trial on 575 patients. After a mean period of 5 years no significant advantage to any of the three prostheses was observed, although there were some differences in the results reported in the Edinburgh and the US trials and possible explanations for these are proposed.

Grantor dc:publisher

The University of Edinburgh

Year dc:date.issued

1990

Author dc:creator

• Bloomfield, Peter

Handle dc:identifier.uri

http://hdl.handle.net/1842/28332

OAI identifier oai:identifier

oai:era.ed.ac.uk:1842/28332