The Effect of Caffeine and Choline on Short-term Memory

This study sought to determine whether caffeine combined with choline could improve short-term memory in healthy adults. The study tested the effect of choline (2 gm) alone and in combination with several concentrations of caffeine (25 mg, 50mg and 100mg) on short-term verbal and visual memory and attention. The Wide Range Assessment of Memory and Learning-2 was utilized. Choline 2 gm + caffeine 25 mg group showed significantly (p<0.05) higher overall memory performance whereas memory performance in the choline 2 gm + caffeine 50 mg group was significantly impaired compared to placebo. The data suggest that specific combinations of caffeine and choline can either facilitate or impair short-term memory in adults with normal cognitive function. Future studies of caffeine and choline combinations will test memory performance in subjects with memory impairment.

Name thesis:degree_name

MS

Level thesis:degree_level

Immediate Access

Discipline thesis:degree_discipline

Pharmacology

Year dc:date.available

2012

Author dc:creator

• Nagrecha, Natasha

Contributors dc:contributor

• David Johnson
• Vincent Giannetti
• Paula Witt-Enderby

• Caffeine
• Choline
• Short term memory
• WRAML 2

Language dc:language

English

Repository record dc:identifier

https://dsc.duq.edu/etd/967

OAI identifier oai:identifier

oai:dsc.duq.edu:etd-1983