{"id":{"repo_id":"dundee","oai_identifier":"oai:discovery.dundee.ac.uk:studenttheses/f8b7f75c-3e88-454e-8323-f1225d3934b2"},"canonical_url":"https://search.dev.ndltd.org/etd/dundee/oai:discovery.dundee.ac.uk:studenttheses/f8b7f75c-3e88-454e-8323-f1225d3934b2","repository":{"repo_id":"dundee","name":"University of Dundee","base_url":"https://discovery.dundee.ac.uk/ws/oai"},"display":{"title":"Multiscale Modelling and Analysis of Plant Cell Signalling Processes and Biomechanics","abstract":"Plant growth, development, and responses to environmental cues are regulated by complex networks of interacting signalling molecules. Signalling pathways activate in response to external or internal cues, leading to a series of signalling processes which end with changes in gene expression. By modifying protein level in this way, specific signalling molecules can enhance or inhibit growth processes at the cell level.<br/><br/>In this thesis, we investigate how cellular signalling events contribute to overall growth of plant tissues. We develop mathematical models describing cellular signalling pathways and their regulation of cell growth processes. Our models consist of ordinary differential equations and partial differential equations describing temporal and spatiotemporal dynamics respectively. We explore the solution structures of our models of cellular signalling processes through analysis and numerical simulation. By solving our cellular models on domains consisting of multiple cells we investigate the contribution of cellular processes to tissue-level phenomena, such as heterogeneous patterning in tissues and growth dynamics. We demonstrate the interplay between growth processes and expression of signalling molecules over time in a plant tissue.","abstract_html":"Plant growth, development, and responses to environmental cues are regulated by complex networks of interacting signalling molecules. Signalling pathways activate in response to external or internal cues, leading to a series of signalling processes which end with changes in gene expression. By modifying protein level in this way, specific signalling molecules can enhance or inhibit growth processes at the cell level.&lt;br/&gt;&lt;br/&gt;In this thesis, we investigate how cellular signalling events contribute to overall growth of plant tissues. We develop mathematical models describing cellular signalling pathways and their regulation of cell growth processes. Our models consist of ordinary differential equations and partial differential equations describing temporal and spatiotemporal dynamics respectively. We explore the solution structures of our models of cellular signalling processes through analysis and numerical simulation. By solving our cellular models on domains consisting of multiple cells we investigate the contribution of cellular processes to tissue-level phenomena, such as heterogeneous patterning in tissues and growth dynamics. We demonstrate the interplay between growth processes and expression of signalling molecules over time in a plant tissue.","abstract_has_math":false,"creators":["Allen, Henry Richard"],"institution":"University of Dundee","degree_name":"Doctor of Philosophy","degree_level":"Doctoral Thesis","degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Ptashnyk, Mariya","Davidson, Fordyce"],"committee_chairs":[],"committee_members":[],"year":2020,"date_issued":"2020","date_published":"2020","updated_at":"2026-07-24T02:08:52Z","subjects":[],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["oai:discovery.dundee.ac.uk:studenttheses/f8b7f75c-3e88-454e-8323-f1225d3934b2"],"render_values":[{"text":"oai:discovery.dundee.ac.uk:studenttheses/f8b7f75c-3e88-454e-8323-f1225d3934b2","href":null,"code":true}]}]},"links":{"outbound_url":"https://discovery.dundee.ac.uk/en/studentTheses/f8b7f75c-3e88-454e-8323-f1225d3934b2","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Ptashnyk, Mariya","Davidson, Fordyce"]},{"key":"dc:contributor.sponsor","label":"Sponsor","values":["Engineering and Physical Sciences Research Council"]},{"key":"dc:creator","label":"Author","values":["Allen, Henry Richard"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2020"]},{"key":"dc:date.issued","label":"Date","values":["2020"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Mathematics"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Dundee"]},{"key":"dc:relation.isreferencedby","label":"Dc Relation Isreferencedby","values":["https://discovery.dundee.ac.uk/en/studentTheses/f8b7f75c-3e88-454e-8323-f1225d3934b2"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["Doctoral Thesis"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["Doctor of Philosophy"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]},{"key":"dc:rights.embargodate","label":"Dc Rights Embargodate","values":["2020-12-31"]},{"key":"dc:rights.embargoreason","label":"Dc Rights Embargoreason","values":["/dk/atira/pure/core/document/studentthesisembargoreason/commercialexploitation"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["oai:discovery.dundee.ac.uk:studenttheses/f8b7f75c-3e88-454e-8323-f1225d3934b2","https://discovery.dundee.ac.uk/en/studentTheses/f8b7f75c-3e88-454e-8323-f1225d3934b2"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://discovery.dundee.ac.uk/files/40913219/HAllen_Thesis.pdf"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Plant growth, development, and responses to environmental cues are regulated by complex networks of interacting signalling molecules. 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By solving our cellular models on domains consisting of multiple cells we investigate the contribution of cellular processes to tissue-level phenomena, such as heterogeneous patterning in tissues and growth dynamics. We demonstrate the interplay between growth processes and expression of signalling molecules over time in a plant tissue."]},{"key":"dc:title","label":"Title","values":["Multiscale Modelling and Analysis of Plant Cell Signalling Processes and Biomechanics"]}]}],"canonical_facts":{"dc:contributor.advisor":["Ptashnyk, Mariya","Davidson, Fordyce"],"dc:contributor.sponsor":["Engineering and Physical Sciences Research Council"],"dc:creator":["Allen, Henry Richard"],"dc:date":["2020"],"dc:date.issued":["2020"],"dc:description.abstract":["Plant growth, development, and responses to environmental cues are regulated by complex networks of interacting signalling molecules. 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