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Duke University

Bayesian and Information-Theoretic Learning of High Dimensional Data

Abstract

dc:description.abstract

<p>The concept of sparseness is harnessed to learn a low dimensional representation of high dimensional data. This sparseness assumption is exploited in multiple ways. In the Bayesian Elastic Net, a small number of correlated features are identified for the response variable. In the sparse Factor Analysis for biomarker trajectories, the high dimensional gene expression data is reduced to a small number of latent factors, each with a prototypical dynamic trajectory. In the Bayesian Graphical LASSO, the inverse covariance matrix of the data distribution is assumed to be sparse, inducing a sparsely connected Gaussian graph. In the nonparametric Mixture of Factor Analyzers, the covariance matrices in the Gaussian Mixture Model are forced to be low-rank, which is closely related to the concept of block sparsity. </p><p>Finally in the information-theoretic projection design, a linear projection matrix is explicitly sought for information-preserving dimensionality reduction. All the methods mentioned above prove to be effective in learning both simulated and real high dimensional datasets.</p>

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Chen, Minhua
Advisor dc:contributor.advisor
  • Carin, Lawrence

Subjects

dc:subject × 9

Identifiers

dc:identifier.*
Handle dc:identifier.uri
https://hdl.handle.net/10161/5588
OAI identifier oai:identifier
oai:dukespace.lib.duke.edu:10161/5588

Chain of custody

source
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Duke University
Base URL
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Last updated
2026-07-24
Source record
OAI-PMH GetRecord
citation

Chen, Minhua. Bayesian and Information-Theoretic Learning of High Dimensional Data. 2012. https://hdl.handle.net/10161/5588