Current research on children with Fragile X Syndrome (FXS) lacks inclusion of qualitative outcomes on the child’s daily occupational performance. Standardized measurements are frequently utilized and provide useful information, however, can be less sensitive to change (Berry Kravis et al., 2013) and miss capturing family perspectives and improvements within meaningful occupations. This research incorporates family perspectives via semi-structured interviews to promote an in-depth understanding about FXS and its impact on child and family occupations in addition to standardized assessment scores through in-depth case study analysis. This study used a mixed method research design examining four male participants who were given sertraline in an in-depth case study analysis. Caregivers were interviewed using a semi-structured interview protocol at baseline and at six months post-treatment to discuss their child, occupations, and any potential impacts of sertraline. Baseline and post-testing standardized assessment results were compared to the occupation centered semi-structured interviews. The data was collected from a pre-existing database in a previous study determining the outcome measures of sertraline. Dedoose software was used to code for categories and themes found in the FXS family interviews. Results indicated that standardized assessments have limited sensitivity to fully capture the lived experiences of families with FXS. Standardized assessments test for performance skills that may not necessarily translate to daily occupations as reported by families. While future practitioners should use standardized assessments in their evaluations, they should also include what families report in their daily lives to fully conclude the child’s abilities to participate and engage in their daily occupations
","abstract_html":"<p>Current research on children with Fragile X Syndrome (FXS) lacks inclusion of qualitative outcomes on the child’s daily occupational performance. Standardized measurements are frequently utilized and provide useful information, however, can be less sensitive to change (Berry Kravis et al., 2013) and miss capturing family perspectives and improvements within meaningful occupations. This research incorporates family perspectives via semi-structured interviews to promote an in-depth understanding about FXS and its impact on child and family occupations in addition to standardized assessment scores through in-depth case study analysis. This study used a mixed method research design examining four male participants who were given sertraline in an in-depth case study analysis. Caregivers were interviewed using a semi-structured interview protocol at baseline and at six months post-treatment to discuss their child, occupations, and any potential impacts of sertraline. Baseline and post-testing standardized assessment results were compared to the occupation centered semi-structured interviews. The data was collected from a pre-existing database in a previous study determining the outcome measures of sertraline. Dedoose software was used to code for categories and themes found in the FXS family interviews. Results indicated that standardized assessments have limited sensitivity to fully capture the lived experiences of families with FXS. Standardized assessments test for performance skills that may not necessarily translate to daily occupations as reported by families. While future practitioners should use standardized assessments in their evaluations, they should also include what families report in their daily lives to fully conclude the child’s abilities to participate and engage in their daily occupations</p>","abstract_has_math":false,"creators":["Ye, Tracy P","Mendoza, Decerie A","Javier, Elena A","Dualan, Martina C"],"institution":null,"degree_name":"Master of Science in Occupational Therapy","degree_level":"Capstone Project","degree_discipline":"Occupational Therapy","degree_department":null,"school":null,"contributors":["Laura Greiss Hess, PhD, OTR/L"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2019,"date_issued":"2019-05-01T07:00:00Z","date_published":"2019-05-01T07:00:00Z","updated_at":"2026-07-24T02:04:51Z","subjects":["Occupation","Fragile X Syndrome","Family Perspectives","Sertraline","Interviews","Neurodevelopmental Disorders","Occupational Therapy"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://scholar.dominican.edu/occupational-therapy-capstone-projects/1","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Laura Greiss Hess, PhD, OTR/L"]},{"key":"dc:creator","label":"Author","values":["Ye, Tracy P","Mendoza, Decerie A","Javier, Elena A","Dualan, Martina C"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2022-12-01T08:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Occupational Therapy"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Capstone Project"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science in Occupational Therapy"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Occupation","Fragile X Syndrome","Family Perspectives","Sertraline","Interviews","Neurodevelopmental Disorders","Occupational Therapy"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://scholar.dominican.edu/occupational-therapy-capstone-projects/1"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Current research on children with Fragile X Syndrome (FXS) lacks inclusion of qualitative outcomes on the child’s daily occupational performance. Standardized measurements are frequently utilized and provide useful information, however, can be less sensitive to change (Berry Kravis et al., 2013) and miss capturing family perspectives and improvements within meaningful occupations. This research incorporates family perspectives via semi-structured interviews to promote an in-depth understanding about FXS and its impact on child and family occupations in addition to standardized assessment scores through in-depth case study analysis. This study used a mixed method research design examining four male participants who were given sertraline in an in-depth case study analysis. Caregivers were interviewed using a semi-structured interview protocol at baseline and at six months post-treatment to discuss their child, occupations, and any potential impacts of sertraline. Baseline and post-testing standardized assessment results were compared to the occupation centered semi-structured interviews. The data was collected from a pre-existing database in a previous study determining the outcome measures of sertraline. Dedoose software was used to code for categories and themes found in the FXS family interviews. Results indicated that standardized assessments have limited sensitivity to fully capture the lived experiences of families with FXS. Standardized assessments test for performance skills that may not necessarily translate to daily occupations as reported by families. While future practitioners should use standardized assessments in their evaluations, they should also include what families report in their daily lives to fully conclude the child’s abilities to participate and engage in their daily occupations
"]},{"key":"dc:title","label":"Title","values":["Effects of Sertraline Treatment for Young Children with Fragile X Syndrome: Family Perspectives via Case Studies"]}]}],"canonical_facts":{"dc:contributor":["Laura Greiss Hess, PhD, OTR/L"],"dc:creator":["Ye, Tracy P","Mendoza, Decerie A","Javier, Elena A","Dualan, Martina C"],"dc:date.available":["2022-12-01T08:00:00Z"],"dc:description.abstract":["Current research on children with Fragile X Syndrome (FXS) lacks inclusion of qualitative outcomes on the child’s daily occupational performance. Standardized measurements are frequently utilized and provide useful information, however, can be less sensitive to change (Berry Kravis et al., 2013) and miss capturing family perspectives and improvements within meaningful occupations. This research incorporates family perspectives via semi-structured interviews to promote an in-depth understanding about FXS and its impact on child and family occupations in addition to standardized assessment scores through in-depth case study analysis. This study used a mixed method research design examining four male participants who were given sertraline in an in-depth case study analysis. Caregivers were interviewed using a semi-structured interview protocol at baseline and at six months post-treatment to discuss their child, occupations, and any potential impacts of sertraline. Baseline and post-testing standardized assessment results were compared to the occupation centered semi-structured interviews. The data was collected from a pre-existing database in a previous study determining the outcome measures of sertraline. Dedoose software was used to code for categories and themes found in the FXS family interviews. Results indicated that standardized assessments have limited sensitivity to fully capture the lived experiences of families with FXS. Standardized assessments test for performance skills that may not necessarily translate to daily occupations as reported by families. While future practitioners should use standardized assessments in their evaluations, they should also include what families report in their daily lives to fully conclude the child’s abilities to participate and engage in their daily occupations
"],"dc:identifier":["https://scholar.dominican.edu/occupational-therapy-capstone-projects/1"],"dc:subject":["Occupation","Fragile X Syndrome","Family Perspectives","Sertraline","Interviews","Neurodevelopmental Disorders","Occupational Therapy"],"dc:title":["Effects of Sertraline Treatment for Young Children with Fragile X Syndrome: Family Perspectives via Case Studies"],"thesis:degree_discipline":["Occupational Therapy"],"thesis:degree_level":["Capstone Project"],"thesis:degree_name":["Master of Science in Occupational Therapy"]},"updated_at":"2026-07-24T02:04:51Z"}