{"id":{"repo_id":"dialnet","oai_identifier":"oai:dialnet.unirioja.es:TES0000000830"},"canonical_url":"https://search.dev.ndltd.org/etd/dialnet/oai:dialnet.unirioja.es:TES0000000830","repository":{"repo_id":"dialnet","name":"Dialnet","base_url":"https://dialnet.unirioja.es/oaites/OAIHandler"},"display":{"title":"Rutas de señalización intracelular que regulan la apoptosis inducida por lovastatina en neuroblastos fetales de rata","abstract":"The aim of this Thesis has been to study the intracellular signals and molecular mechanisms that control neuronal apoptosis. We have mainly focused our attention to the survival pathways Duch as RAS/RAF/MAP-kinases, PI3-K/PKB, as well as death pathways, stress-activated MAP-kinases (JUN-kinases and p38).","abstract_html":"The aim of this Thesis has been to study the intracellular signals and molecular mechanisms that control neuronal apoptosis. We have mainly focused our attention to the survival pathways Duch as RAS/RAF/MAP-kinases, PI3-K/PKB, as well as death pathways, stress-activated MAP-kinases (JUN-kinases and p38).","abstract_has_math":false,"creators":["Cerezo Guisado, María Isabel"],"institution":"Universidad de Extremadura (España)","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":["Bragado González, María Julia (Universidad de Extremadura)","Lorenzo Benayas, María Jesús (Universidad de Extremadura)"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2006,"date_issued":"2006","date_published":"2006","updated_at":"2026-07-24T06:26:35Z","subjects":[],"languages":["spa"],"rights":["LICENCIA DE USO: Los documentos a texto completo incluidos en Dialnet son de acceso libre y propiedad de sus autores y/o editores. 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Por tanto, cualquier acto de reproducción, distribución, comunicación pública y/o transformación total o parcial requiere el consentimiento expreso y escrito de aquéllos. Cualquier enlace al texto completo de estos documentos deberá hacerse a través de la URL oficial de éstos en Dialnet. Más información: https://dialnet.unirioja.es/info/derechosOAI | INTELLECTUAL PROPERTY RIGHTS STATEMENT: Full text documents hosted by Dialnet are protected by copyright and/or related rights. This digital object is accessible without charge, but its use is subject to the licensing conditions set by its authors or editors. Unless expressly stated otherwise in the licensing conditions, you are free to linking, browsing, printing and making a copy for your own personal purposes. All other acts of reproduction and communication to the public are subject to the licensing conditions expressed by editors and authors and require consent from them. 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En concreto se ha estudiado el efecto de la lovastatina en las rutas de transducción de señales, principalmente en las rutas reguladoras de la supervivencia celular como las de RAS/RAF/MAP-quinasas y PI3-K/PKB, así como en las rutas mediadoras de muerte celular, MAP-quinasas activadas por estrés (JUN-quinasas y p38)."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Rutas de señalización intracelular que regulan la apoptosis inducida por lovastatina en neuroblastos fetales de rata"]}]}],"canonical_facts":{"dc:contributor":["Bragado González, María Julia (Universidad de Extremadura)","Lorenzo Benayas, María Jesús (Universidad de Extremadura)"],"dc:creator":["Cerezo Guisado, María Isabel"],"dc:date":["2006"],"dc:description":["The aim of this Thesis has been to study the intracellular signals and molecular mechanisms that control neuronal apoptosis. 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En concreto se ha estudiado el efecto de la lovastatina en las rutas de transducción de señales, principalmente en las rutas reguladoras de la supervivencia celular como las de RAS/RAF/MAP-quinasas y PI3-K/PKB, así como en las rutas mediadoras de muerte celular, MAP-quinasas activadas por estrés (JUN-quinasas y p38)."],"dc:format":["application/pdf"],"dc:identifier":["https://dialnet.unirioja.es/servlet/oaites?codigo=1275","(Tesis) ISBN 84-7723-754-9"],"dc:language":["spa"],"dc:publisher":["Universidad de Extremadura (España)"],"dc:rights":["LICENCIA DE USO: Los documentos a texto completo incluidos en Dialnet son de acceso libre y propiedad de sus autores y/o editores. Por tanto, cualquier acto de reproducción, distribución, comunicación pública y/o transformación total o parcial requiere el consentimiento expreso y escrito de aquéllos. Cualquier enlace al texto completo de estos documentos deberá hacerse a través de la URL oficial de éstos en Dialnet. 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