{"id":{"repo_id":"dialnet","oai_identifier":"oai:dialnet.unirioja.es:TES0000000264"},"canonical_url":"https://search.dev.ndltd.org/etd/dialnet/oai:dialnet.unirioja.es:TES0000000264","repository":{"repo_id":"dialnet","name":"Dialnet","base_url":"https://dialnet.unirioja.es/oaites/OAIHandler"},"display":{"title":"Implicaciones de la NDP reductasa en la progresión de las horquillas de replicación en Escherichia coli","abstract":"NDP reductase is the only specific enzyme required for the enzymatic synthesis of the precursors of DNA and it is a part of the Nucleotides Synthesis Complex. In this work we have analysed the replication fork progression in a nrdA101 mutant, which has a thermosensitive NDP reductase. We have proved that the Nucleotides Synthesis Complex and the Replication Complex are associated in a Replication Hyperstructure.","abstract_html":"NDP reductase is the only specific enzyme required for the enzymatic synthesis of the precursors of DNA and it is a part of the Nucleotides Synthesis Complex. In this work we have analysed the replication fork progression in a nrdA101 mutant, which has a thermosensitive NDP reductase. 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Cualquier enlace al texto completo de estos documentos deberá hacerse a través de la URL oficial de éstos en Dialnet. Más información: https://dialnet.unirioja.es/info/derechosOAI | INTELLECTUAL PROPERTY RIGHTS STATEMENT: Full text documents hosted by Dialnet are protected by copyright and/or related rights. This digital object is accessible without charge, but its use is subject to the licensing conditions set by its authors or editors. Unless expressly stated otherwise in the licensing conditions, you are free to linking, browsing, printing and making a copy for your own personal purposes. All other acts of reproduction and communication to the public are subject to the licensing conditions expressed by editors and authors and require consent from them. Any link to this document should be made using its official URL in Dialnet. 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Por tanto, cualquier acto de reproducción, distribución, comunicación pública y/o transformación total o parcial requiere el consentimiento expreso y escrito de aquéllos. Cualquier enlace al texto completo de estos documentos deberá hacerse a través de la URL oficial de éstos en Dialnet. Más información: https://dialnet.unirioja.es/info/derechosOAI | INTELLECTUAL PROPERTY RIGHTS STATEMENT: Full text documents hosted by Dialnet are protected by copyright and/or related rights. This digital object is accessible without charge, but its use is subject to the licensing conditions set by its authors or editors. Unless expressly stated otherwise in the licensing conditions, you are free to linking, browsing, printing and making a copy for your own personal purposes. All other acts of reproduction and communication to the public are subject to the licensing conditions expressed by editors and authors and require consent from them. 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We have proved that the Nucleotides Synthesis Complex and the Replication Complex are associated in a Replication Hyperstructure.","La NDP reductasa es la única enzima requerida directamente para la biosíntesis de los precursores del DNA y está formando parte del Complejo de Síntesis de Nucleótidos. En este trabajo se ha analizado la progresión de las horquillas de replicación en un mutante nrdA101 que posee un NDP reductasa termosensible, comprobándose que el Complejo se Síntesis de Nucleótidos y el de Replicación están asociados formando una Hiperestructura de Replicación."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Implicaciones de la NDP reductasa en la progresión de las horquillas de replicación en Escherichia coli"]}]}],"canonical_facts":{"dc:contributor":["Jiménez Sánchez, Alfonso (Universidad de Extremadura)","Guzmán Cabañas, María Elena (Universidad de Extremadura)"],"dc:creator":["Guarino Almeida, Estrella"],"dc:date":["2006"],"dc:description":["NDP reductase is the only specific enzyme required for the enzymatic synthesis of the precursors of DNA and it is a part of the Nucleotides Synthesis Complex. In this work we have analysed the replication fork progression in a nrdA101 mutant, which has a thermosensitive NDP reductase. We have proved that the Nucleotides Synthesis Complex and the Replication Complex are associated in a Replication Hyperstructure.","La NDP reductasa es la única enzima requerida directamente para la biosíntesis de los precursores del DNA y está formando parte del Complejo de Síntesis de Nucleótidos. En este trabajo se ha analizado la progresión de las horquillas de replicación en un mutante nrdA101 que posee un NDP reductasa termosensible, comprobándose que el Complejo se Síntesis de Nucleótidos y el de Replicación están asociados formando una Hiperestructura de Replicación."],"dc:format":["application/pdf"],"dc:identifier":["https://dialnet.unirioja.es/servlet/oaites?codigo=615","(Tesis) ISBN 84-7723-734-4"],"dc:language":["spa"],"dc:publisher":["Universidad de Extremadura (España)"],"dc:rights":["LICENCIA DE USO: Los documentos a texto completo incluidos en Dialnet son de acceso libre y propiedad de sus autores y/o editores. Por tanto, cualquier acto de reproducción, distribución, comunicación pública y/o transformación total o parcial requiere el consentimiento expreso y escrito de aquéllos. Cualquier enlace al texto completo de estos documentos deberá hacerse a través de la URL oficial de éstos en Dialnet. Más información: https://dialnet.unirioja.es/info/derechosOAI | INTELLECTUAL PROPERTY RIGHTS STATEMENT: Full text documents hosted by Dialnet are protected by copyright and/or related rights. This digital object is accessible without charge, but its use is subject to the licensing conditions set by its authors or editors. Unless expressly stated otherwise in the licensing conditions, you are free to linking, browsing, printing and making a copy for your own personal purposes. All other acts of reproduction and communication to the public are subject to the licensing conditions expressed by editors and authors and require consent from them. Any link to this document should be made using its official URL in Dialnet. More info: https://dialnet.unirioja.es/info/derechosOAI"],"dc:title":["Implicaciones de la NDP reductasa en la progresión de las horquillas de replicación en Escherichia coli"],"dc:type":["text (thesis)"]},"updated_at":"2026-07-24T06:26:35Z"}