{"id":{"repo_id":"dialnet","oai_identifier":"oai:dialnet.unirioja.es:TES0000000261"},"canonical_url":"https://search.dev.ndltd.org/etd/dialnet/oai:dialnet.unirioja.es:TES0000000261","repository":{"repo_id":"dialnet","name":"Dialnet","base_url":"https://dialnet.unirioja.es/oaites/OAIHandler"},"display":{"title":"Inducción térmica del inicio de la replicación cromosómica en Escherichia coli","abstract":"A shift-up of ten or more degrees in the growth temperature of an Escherichia coli culture causes induction of extra rounds of chromosome replication. This heat-induced replication (HIR) initiates at oriC, is transitory, requires RNase H1 and RecA and requires neither RNA polymerase activity nor de novo protein synthesis. HIR is neither related to SDR nor induced by the heat shock response. A thermodynamic alteration of oriC structure or of membrane fluidity could explain the observed HIR.","abstract_html":"A shift-up of ten or more degrees in the growth temperature of an Escherichia coli culture causes induction of extra rounds of chromosome replication. This heat-induced replication (HIR) initiates at oriC, is transitory, requires RNase H1 and RecA and requires neither RNA polymerase activity nor de novo protein synthesis. HIR is neither related to SDR nor induced by the heat shock response. A thermodynamic alteration of oriC structure or of membrane fluidity could explain the observed HIR.","abstract_has_math":false,"creators":["Botello Cambero, Emilia Carmen"],"institution":"Universidad de Extremadura (España)","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":["Jiménez Sánchez, Alfonso (Universidad de Extremadura)"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1994,"date_issued":"1994","date_published":"1994","updated_at":"2026-07-24T06:26:35Z","subjects":[],"languages":["spa"],"rights":["LICENCIA DE USO: Los documentos a texto completo incluidos en Dialnet son de acceso libre y propiedad de sus autores y/o editores. Por tanto, cualquier acto de reproducción, distribución, comunicación pública y/o transformación total o parcial requiere el consentimiento expreso y escrito de aquéllos. Cualquier enlace al texto completo de estos documentos deberá hacerse a través de la URL oficial de éstos en Dialnet. Más información: https://dialnet.unirioja.es/info/derechosOAI | INTELLECTUAL PROPERTY RIGHTS STATEMENT: Full text documents hosted by Dialnet are protected by copyright and/or related rights. This digital object is accessible without charge, but its use is subject to the licensing conditions set by its authors or editors. Unless expressly stated otherwise in the licensing conditions, you are free to linking, browsing, printing and making a copy for your own personal purposes. All other acts of reproduction and communication to the public are subject to the licensing conditions expressed by editors and authors and require consent from them. Any link to this document should be made using its official URL in Dialnet. More info: https://dialnet.unirioja.es/info/derechosOAI"],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["(Tesis) ISBN 84-7723-725-5"],"render_values":[{"text":"(Tesis) ISBN 84-7723-725-5","href":null,"code":true}]}]},"links":{"outbound_url":"https://dialnet.unirioja.es/servlet/oaites?codigo=603","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Jiménez Sánchez, Alfonso (Universidad de Extremadura)"]},{"key":"dc:creator","label":"Author","values":["Botello Cambero, Emilia Carmen"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["1994"]},{"key":"dc:publisher","label":"Institution","values":["Universidad de Extremadura (España)"]},{"key":"dc:type","label":"Dc Type","values":["text (thesis)"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["spa"]},{"key":"dc:rights","label":"Dc Rights","values":["LICENCIA DE USO: Los documentos a texto completo incluidos en Dialnet son de acceso libre y propiedad de sus autores y/o editores. Por tanto, cualquier acto de reproducción, distribución, comunicación pública y/o transformación total o parcial requiere el consentimiento expreso y escrito de aquéllos. Cualquier enlace al texto completo de estos documentos deberá hacerse a través de la URL oficial de éstos en Dialnet. Más información: https://dialnet.unirioja.es/info/derechosOAI | INTELLECTUAL PROPERTY RIGHTS STATEMENT: Full text documents hosted by Dialnet are protected by copyright and/or related rights. This digital object is accessible without charge, but its use is subject to the licensing conditions set by its authors or editors. Unless expressly stated otherwise in the licensing conditions, you are free to linking, browsing, printing and making a copy for your own personal purposes. All other acts of reproduction and communication to the public are subject to the licensing conditions expressed by editors and authors and require consent from them. Any link to this document should be made using its official URL in Dialnet. More info: https://dialnet.unirioja.es/info/derechosOAI"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://dialnet.unirioja.es/servlet/oaites?codigo=603","(Tesis) ISBN 84-7723-725-5"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["A shift-up of ten or more degrees in the growth temperature of an Escherichia coli culture causes induction of extra rounds of chromosome replication. This heat-induced replication (HIR) initiates at oriC, is transitory, requires RNase H1 and RecA and requires neither RNA polymerase activity nor de novo protein synthesis. HIR is neither related to SDR nor induced by the heat shock response. A thermodynamic alteration of oriC structure or of membrane fluidity could explain the observed HIR.","Un aumento de diez o más grados en la temperatura de incubación de un cultivo de Escherichia coli induce ciclos de replicación extras. Esta replicación inducida por calor (HIR) inicia en oriC, es transitoria, requiere Rnase H1 y RecA y no requiere la actividad de la RNA polimerasa ni síntesis de proteínas de novo. HIR no está relacionada con SDR ni con la respuesta de choque térmico. Una alteración termodinámica de la estructura de oriC o de la fluidez de membrana podría justificar HIR."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Inducción térmica del inicio de la replicación cromosómica en Escherichia coli"]}]}],"canonical_facts":{"dc:contributor":["Jiménez Sánchez, Alfonso (Universidad de Extremadura)"],"dc:creator":["Botello Cambero, Emilia Carmen"],"dc:date":["1994"],"dc:description":["A shift-up of ten or more degrees in the growth temperature of an Escherichia coli culture causes induction of extra rounds of chromosome replication. This heat-induced replication (HIR) initiates at oriC, is transitory, requires RNase H1 and RecA and requires neither RNA polymerase activity nor de novo protein synthesis. HIR is neither related to SDR nor induced by the heat shock response. A thermodynamic alteration of oriC structure or of membrane fluidity could explain the observed HIR.","Un aumento de diez o más grados en la temperatura de incubación de un cultivo de Escherichia coli induce ciclos de replicación extras. Esta replicación inducida por calor (HIR) inicia en oriC, es transitoria, requiere Rnase H1 y RecA y no requiere la actividad de la RNA polimerasa ni síntesis de proteínas de novo. HIR no está relacionada con SDR ni con la respuesta de choque térmico. Una alteración termodinámica de la estructura de oriC o de la fluidez de membrana podría justificar HIR."],"dc:format":["application/pdf"],"dc:identifier":["https://dialnet.unirioja.es/servlet/oaites?codigo=603","(Tesis) ISBN 84-7723-725-5"],"dc:language":["spa"],"dc:publisher":["Universidad de Extremadura (España)"],"dc:rights":["LICENCIA DE USO: Los documentos a texto completo incluidos en Dialnet son de acceso libre y propiedad de sus autores y/o editores. Por tanto, cualquier acto de reproducción, distribución, comunicación pública y/o transformación total o parcial requiere el consentimiento expreso y escrito de aquéllos. Cualquier enlace al texto completo de estos documentos deberá hacerse a través de la URL oficial de éstos en Dialnet. Más información: https://dialnet.unirioja.es/info/derechosOAI | INTELLECTUAL PROPERTY RIGHTS STATEMENT: Full text documents hosted by Dialnet are protected by copyright and/or related rights. This digital object is accessible without charge, but its use is subject to the licensing conditions set by its authors or editors. Unless expressly stated otherwise in the licensing conditions, you are free to linking, browsing, printing and making a copy for your own personal purposes. All other acts of reproduction and communication to the public are subject to the licensing conditions expressed by editors and authors and require consent from them. Any link to this document should be made using its official URL in Dialnet. More info: https://dialnet.unirioja.es/info/derechosOAI"],"dc:title":["Inducción térmica del inicio de la replicación cromosómica en Escherichia coli"],"dc:type":["text (thesis)"]},"updated_at":"2026-07-24T06:26:35Z"}