Endothelial dysfunction as a pathogenetic factor in cardiovascular diseases

Cardiovascular disease (CVD) is a major cause of morbidity and mortality around the world. The risk factors and treatments have been thoroughly researched and documented, but one crucial element is endothelial dysfunction. Endothelial dysfunction is defined by the reduction of NO-induced vasodilation. The strongest link between endothelial dysfunction and CVD is atherosclerosis. The relationship between endothelial dysfunction and CVD has been solidified by reviewing the mechanisms that cause endothelial dysfunction as well as the major therapies that have shown that reducing or protecting against endothelial dysfunction can lead to better clinical outcomes in relation to CVD.

Department dc:contributor.department

DE--Általános Orvostudományi Kar

Author dc:creator

• Elhayes, Sarah

Advisor dc:contributor.advisor

• Szentmiklósi, József András

• Endothelial dysfunction
• Cardiovascular diseases

Language dc:language.iso

en

Handle dc:identifier.uri

http://hdl.handle.net/2437/336479

OAI identifier oai:identifier

oai:dea.lib.unideb.hu:2437/336479