{"id":{"repo_id":"debrecen","oai_identifier":"oai:dea.lib.unideb.hu:2437/307535"},"canonical_url":"https://search.dev.ndltd.org/etd/debrecen/oai:dea.lib.unideb.hu:2437/307535","repository":{"repo_id":"debrecen","name":"University of Debrecen","base_url":"https://dea.lib.unideb.hu/server/oai/request"},"display":{"title":"The preventive and therapeutic effects of molecular Hydrogen","abstract":"Hydrogen gas, which was previously considered to be physiologically inert in mammalian cells, is now considered as a novel selective antioxidant with potentially therapeutic applications and minor adverse effects. Its selectivity presents through its mild effect that is enough neither to disturb metabolic redox reactions nor to affect ROS, which function in cell signaling. This thesis reviewed the development of hydrogen in therapy, which includes its characteristic, production, possible underlying mechanisms and therapeutic applications. However, the primary targets of molecular hydrogen still remain elusive. Thus, further research is needed to determine the underlying mechanisms of therapeutic effects, antioxidant, anti-inflammatory and apoptotic ways, which will certainly advance the important molecule in clinical applications.","abstract_html":"Hydrogen gas, which was previously considered to be physiologically inert in mammalian cells, is now considered as a novel selective antioxidant with potentially therapeutic applications and minor adverse effects. Its selectivity presents through its mild effect that is enough neither to disturb metabolic redox reactions nor to affect ROS, which function in cell signaling. This thesis reviewed the development of hydrogen in therapy, which includes its characteristic, production, possible underlying mechanisms and therapeutic applications. However, the primary targets of molecular hydrogen still remain elusive. Thus, further research is needed to determine the underlying mechanisms of therapeutic effects, antioxidant, anti-inflammatory and apoptotic ways, which will certainly advance the important molecule in clinical applications.","abstract_has_math":false,"creators":["Nguyen, Mai My Hong"],"institution":null,"degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":"DE--Gyógyszerésztudományi Kar","school":null,"contributors":[],"advisors":["Bak, István"],"committee_chairs":[],"committee_members":[],"year":null,"date_issued":"","date_published":null,"updated_at":"2026-07-27T19:13:57Z","subjects":["molecular Hydrogen"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2437/307535","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Bak, István"]},{"key":"dc:contributor.department","label":"Department","values":["DE--Gyógyszerésztudományi Kar"]},{"key":"dc:creator","label":"Author","values":["Nguyen, Mai My Hong"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2021-04-27T06:52:46Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2021-04-27T06:52:46Z"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["molecular Hydrogen"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/2437/307535"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Hydrogen gas, which was previously considered to be physiologically inert in mammalian cells, is now considered as a novel selective antioxidant with potentially therapeutic applications and minor adverse effects. Its selectivity presents through its mild effect that is enough neither to disturb metabolic redox reactions nor to affect ROS, which function in cell signaling. This thesis reviewed the development of hydrogen in therapy, which includes its characteristic, production, possible underlying mechanisms and therapeutic applications. However, the primary targets of molecular hydrogen still remain elusive. Thus, further research is needed to determine the underlying mechanisms of therapeutic effects, antioxidant, anti-inflammatory and apoptotic ways, which will certainly advance the important molecule in clinical applications."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["egységes, osztatlan"]},{"key":"dc:title","label":"Title","values":["The preventive and therapeutic effects of molecular Hydrogen"]}]}],"canonical_facts":{"dc:contributor.advisor":["Bak, István"],"dc:contributor.department":["DE--Gyógyszerésztudományi Kar"],"dc:creator":["Nguyen, Mai My Hong"],"dc:date.accessioned":["2021-04-27T06:52:46Z"],"dc:date.available":["2021-04-27T06:52:46Z"],"dc:description.abstract":["Hydrogen gas, which was previously considered to be physiologically inert in mammalian cells, is now considered as a novel selective antioxidant with potentially therapeutic applications and minor adverse effects. Its selectivity presents through its mild effect that is enough neither to disturb metabolic redox reactions nor to affect ROS, which function in cell signaling. This thesis reviewed the development of hydrogen in therapy, which includes its characteristic, production, possible underlying mechanisms and therapeutic applications. However, the primary targets of molecular hydrogen still remain elusive. Thus, further research is needed to determine the underlying mechanisms of therapeutic effects, antioxidant, anti-inflammatory and apoptotic ways, which will certainly advance the important molecule in clinical applications."],"dc:description.degree":["egységes, osztatlan"],"dc:identifier.uri":["http://hdl.handle.net/2437/307535"],"dc:language.iso":["en"],"dc:subject":["molecular Hydrogen"],"dc:title":["The preventive and therapeutic effects of molecular Hydrogen"]},"updated_at":"2026-07-27T19:13:57Z"}