AN INVESTIGATION OF THE FEASIBILITY OF BIOMETHYLATION FOR GROUP IV METALS AND COMPOUNDS
type: CreativeWork
description: Methylmetal compounds are more toxic than their inorganic counterparts. The process of environmental methylation of some toxic metals and metalloids has been briefly reviewed. Group IV metals (Sn, Pb) have found widespread industrial use in recent years. Use of lead and organolead chemicals has declined but tin and organotin chemicals production has been increasing. Their methyl derivatives are of comparable toxicity but long terra toxicological studies for tin do not exist. Possible methylation of trimethyllead species in environmental sediment samples was attributed by other workers to a dismutation reaction of the bis trimethyllead sulphide formed by the reaction of trimethyllead species in the presence of biologically produced free sulphide ions. Preparation of bis trimethyltin sulphide, and reaction with artificial daylight radiation proved that the same applies to trimethyltin species. Tetraraethyltin and dimethyltin sulphide trimer were the products of the reactions. Dismutation of trimethyl tin species on the oxo-ligand tropolone suggests that oxygen and sulphur ligands in the environment will play a part in the volatilisation and cycling of tin in the environment. From incubations of deuterated trimethyltin species in a number of sediment samples only fully deuterated tetramethyltin species were detected by ms, suggesting that tetramethyltin can only be produced from dismutation of bis-trimethyltin sulphide. Computer simulation of the ms of methylated, deuterated trimethyltin and mathematical treatment of its ms breaking pattern in the presence of fully deuterated tetramethyltin , set a precedent for future use of deuterated trimethyltin species in such incubation studies. Reactions of lead and tin compounds in aqueous abiotic system with naturally occurring carbonium ion donors like iodomethane, dimethyl sulphide, trimethyl sulphonium iodide and N-trimethyl glycine produced partially methylmetal species but not in all cases. Tetramethylmetal species could …
abstract: Methylmetal compounds are more toxic than their inorganic counterparts. The process of environmental methylation of some toxic metals and metalloids has been briefly reviewed. Group IV metals (Sn, Pb) have found widespread industrial use in recent years. Use of lead and organolead chemicals has declined but tin and organotin chemicals production has been increasing. Their methyl derivatives are of comparable toxicity but long terra toxicological studies for tin do not exist. Possible methylation of trimethyllead species in environmental sediment samples was attributed by other workers to a dismutation reaction of the bis trimethyllead sulphide formed by the reaction of trimethyllead species in the presence of biologically produced free sulphide ions. Preparation of bis trimethyltin sulphide, and reaction with artificial daylight radiation proved that the same applies to trimethyltin species. Tetraraethyltin and dimethyltin sulphide trimer were the products of the reactions. Dismutation of trimethyl tin species on the oxo-ligand tropolone suggests that oxygen and sulphur ligands in the environment will play a part in the volatilisation and cycling of tin in the environment. From incubations of deuterated trimethyltin species in a number of sediment samples only fully deuterated tetramethyltin species were detected by ms, suggesting that tetramethyltin can only be produced from dismutation of bis-trimethyltin sulphide. Computer simulation of the ms of methylated, deuterated trimethyltin and mathematical treatment of its ms breaking pattern in the presence of fully deuterated tetramethyltin , set a precedent for future use of deuterated trimethyltin species in such incubation studies. Reactions of lead and tin compounds in aqueous abiotic system with naturally occurring carbonium ion donors like iodomethane, dimethyl sulphide, trimethyl sulphonium iodide and N-trimethyl glycine produced partially methylmetal species but not in all cases. Tetramethylmetal species could …
author: RAPSOMANIKIS, SPYRIDON
license: https://dora.dmu.ac.uk/bitstreams/2b1a2335-89b8-4f60-a627-d420dac97068/download
date published: 1983-08
date modified: 2026-07-24T06:18:40Z
provider: De Montfort University
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: De Montfort University