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Creighton University

Determining the Difference Between Active and Inactive Caries White Spot Lesions Using Sodium Iodide

Abstract

dc:description.abstract

Identifying the differences between active and inactive white spot caries lesions is presently a challenging task in clinical dentistry. White spot lesions are normally associated with demineralization that has happened (inactive) or is happening (active) to the tooth at a given time. In inactive white spot lesions, the demineralization is at rest and the infectious carious process is stopped. It is important to be able to differentiate an inactive lesion from an active one because inactive lesions can be treated without surgical methods. Avoiding unnecessary repair will preserve the natural structure of the tooth and increase its longevity. We have tested the ability of a concentrated, 11 molar Sodium Iodide (NaI) solution as a radiographic contrast agent to differentiate between active and inactive caries white spot lesions. The hypothesis is that concentrated NaI solution is likely to penetrate into the tooth structure of active, but not inactive, lesions, thereby providing a visual method for distinguishing the activity states. To test this hypothesis, two teeth (one human maxillary 1st molar and one maxillary 3rd molar) with visible white spot lesions were collected for analysis. Photomicrography, radiography and Scanning Electron Microscopy (SEM) assessments were used to study these specimens. Consistent with our hypothesis, radiographic images revealed a high penetration of NaI solution through the enamel of the 1st molar, which had an active white spot lesion, as confirmed by photomicrography and SEM analysis. However, minimal to no NaI penetration was observed through the enamel of the 3rd molar, which was confirmed to have an inactive white spot lesion. While this study is preliminary, new methods to identify active carious lesions have the potential to improve the management of caries and reduce unnecessary restorative measures.

Degree

thesis:*
Grantor dc:publisher
Creighton University
Year dc:date.issued
2014

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Berry, Michael Robert
Advisor dc:contributor.advisor
  • Sanchez, Sonia M.

Rights

dc:rights
Statement dc:rights
  • Copyright is retained by the Author. A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above.
Language dc:language.iso
en_US

Identifiers

dc:identifier.*
Handle dc:identifier.uri
http://hdl.handle.net/10504/49899
OAI identifier oai:identifier
oai:cdr.creighton.edu:10504/49899

Chain of custody

source
Harvested from
Creighton University
Base URL
cdr.creighton.edu/server/oai/request
Last updated
2026-07-24
Source record
OAI-PMH GetRecord
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citation

Berry, Michael Robert. Determining the Difference Between Active and Inactive Caries White Spot Lesions Using Sodium Iodide. Creighton University, 2014. http://hdl.handle.net/10504/49899