{"id":{"repo_id":"creighton","oai_identifier":"oai:cdr.creighton.edu:10504/165926"},"canonical_url":"https://search.dev.ndltd.org/etd/creighton/oai:cdr.creighton.edu:10504/165926","repository":{"repo_id":"creighton","name":"Creighton University","base_url":"https://cdr.creighton.edu/server/oai/request"},"display":{"title":"Biodegradable Polymeric Ion Releasing Fillers","abstract":"Dental sealants are a highly effective tool used by dentists to prevent occlusal caries in children by sealing pits and fissures of molars. However, polymerization shrinkage can lead to marginal leakage and secondary caries over time. Biodegradeable polymeric ion-releasing fillers (PIRFs) synthesized from alginate have the potential to be a useful sustainable tool that can provide sustained pH independent release of ions that promote remineralization in enamel. These PIRFs were rinsed to remove excess calcium ions and then charged with a 0.9M NaF solution or 3-6M K2HPO4 solution. After being soaked in these solutions the PIRFs exhibited effective ion release into water. When incorporated into BisGMA/TEGMA sealants adequate depth of cure and degree of conversion properties were observed. PIRFs promote a solution that promotes remineralization of enamel which may also help reduce secondary caries risk while also being sourced from renewable alginate.","abstract_html":"Dental sealants are a highly effective tool used by dentists to prevent occlusal caries in children by sealing pits and fissures of molars. However, polymerization shrinkage can lead to marginal leakage and secondary caries over time. Biodegradeable polymeric ion-releasing fillers (PIRFs) synthesized from alginate have the potential to be a useful sustainable tool that can provide sustained pH independent release of ions that promote remineralization in enamel. These PIRFs were rinsed to remove excess calcium ions and then charged with a 0.9M NaF solution or 3-6M K2HPO4 solution. After being soaked in these solutions the PIRFs exhibited effective ion release into water. When incorporated into BisGMA/TEGMA sealants adequate depth of cure and degree of conversion properties were observed. PIRFs promote a solution that promotes remineralization of enamel which may also help reduce secondary caries risk while also being sourced from renewable alginate.","abstract_has_math":false,"creators":["Brizuela Rapalo, William, Lizandro"],"institution":"Creighton University","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Gross, Stephen"],"committee_chairs":[],"committee_members":[],"year":2026,"date_issued":"2026-04-09","date_published":"2026-04-09","updated_at":"2026-07-24T01:50:02Z","subjects":[],"languages":["en_US"],"rights":["Copyright is retained by the Author. A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://cdr.creighton.edu/handle/10504/165926","outbound_label":"Repository record","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Gross, Stephen"]},{"key":"dc:creator","label":"Author","values":["Brizuela Rapalo, William, Lizandro"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2026-06-25T14:09:29Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2026-06-25T14:09:29Z"]},{"key":"dc:date.issued","label":"Date","values":["2026-04-09"]},{"key":"dc:publisher","label":"Institution","values":["Creighton University"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en_US"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright is retained by the Author. A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://cdr.creighton.edu/handle/10504/165926"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["2026"]},{"key":"dc:description.abstract","label":"Abstract","values":["Dental sealants are a highly effective tool used by dentists to prevent occlusal caries in children by sealing pits and fissures of molars. However, polymerization shrinkage can lead to marginal leakage and secondary caries over time. Biodegradeable polymeric ion-releasing fillers (PIRFs) synthesized from alginate have the potential to be a useful sustainable tool that can provide sustained pH independent release of ions that promote remineralization in enamel. These PIRFs were rinsed to remove excess calcium ions and then charged with a 0.9M NaF solution or 3-6M K2HPO4 solution. After being soaked in these solutions the PIRFs exhibited effective ion release into water. When incorporated into BisGMA/TEGMA sealants adequate depth of cure and degree of conversion properties were observed. PIRFs promote a solution that promotes remineralization of enamel which may also help reduce secondary caries risk while also being sourced from renewable alginate."]},{"key":"dc:title","label":"Title","values":["Biodegradable Polymeric Ion Releasing Fillers"]}]}],"canonical_facts":{"dc:contributor.advisor":["Gross, Stephen"],"dc:creator":["Brizuela Rapalo, William, Lizandro"],"dc:date.accessioned":["2026-06-25T14:09:29Z"],"dc:date.available":["2026-06-25T14:09:29Z"],"dc:date.issued":["2026-04-09"],"dc:description":["2026"],"dc:description.abstract":["Dental sealants are a highly effective tool used by dentists to prevent occlusal caries in children by sealing pits and fissures of molars. However, polymerization shrinkage can lead to marginal leakage and secondary caries over time. Biodegradeable polymeric ion-releasing fillers (PIRFs) synthesized from alginate have the potential to be a useful sustainable tool that can provide sustained pH independent release of ions that promote remineralization in enamel. These PIRFs were rinsed to remove excess calcium ions and then charged with a 0.9M NaF solution or 3-6M K2HPO4 solution. After being soaked in these solutions the PIRFs exhibited effective ion release into water. When incorporated into BisGMA/TEGMA sealants adequate depth of cure and degree of conversion properties were observed. PIRFs promote a solution that promotes remineralization of enamel which may also help reduce secondary caries risk while also being sourced from renewable alginate."],"dc:identifier.uri":["https://cdr.creighton.edu/handle/10504/165926"],"dc:language.iso":["en_US"],"dc:publisher":["Creighton University"],"dc:rights":["Copyright is retained by the Author. A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."],"dc:title":["Biodegradable Polymeric Ion Releasing Fillers"],"dc:type":["Thesis"]},"updated_at":"2026-07-24T01:50:02Z"}