{"id":{"repo_id":"creighton","oai_identifier":"oai:cdr.creighton.edu:10504/118415"},"canonical_url":"https://search.dev.ndltd.org/etd/creighton/oai:cdr.creighton.edu:10504/118415","repository":{"repo_id":"creighton","name":"Creighton University","base_url":"https://cdr.creighton.edu/server/oai/request"},"display":{"title":"The Mechanism of the Action of Gastrin on Guinea Pig Ileum Smooth Muscle","abstract":"Over fifty years elapsed between the discovery that a crude antral extract could increase the acid content of the stomach and the characterization of the specific secretory hormone, gastrin. | Gastrin was discovered to have a spectrum of actions upon the gastrointestinal tract. Vizi et al. produced direct evidence that gastrin caused the release of acetylcholine from Auerbach's plexus of guinea pig terminal ileum which, in turn, caused the muscle to contract. The purpose of this study was to verify the findings of Vizi et al. and to describe the mechanism and sites at which this action of gastrin was mediated.","abstract_html":"Over fifty years elapsed between the discovery that a crude antral extract could increase the acid content of the stomach and the characterization of the specific secretory hormone, gastrin. | Gastrin was discovered to have a spectrum of actions upon the gastrointestinal tract. Vizi et al. produced direct evidence that gastrin caused the release of acetylcholine from Auerbach's plexus of guinea pig terminal ileum which, in turn, caused the muscle to contract. The purpose of this study was to verify the findings of Vizi et al. and to describe the mechanism and sites at which this action of gastrin was mediated.","abstract_has_math":false,"creators":["Morelock, Michael Dennis"],"institution":"Creighton University","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Magee, Donal F."],"committee_chairs":[],"committee_members":[],"year":1973,"date_issued":"1973","date_published":"1973","updated_at":"2026-07-24T01:50:57Z","subjects":[],"languages":["en_US"],"rights":["A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10504/118415","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Magee, Donal F."]},{"key":"dc:creator","label":"Author","values":["Morelock, Michael Dennis"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2018-06-18T15:55:50Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2018-06-18T15:55:50Z"]},{"key":"dc:date.issued","label":"Date","values":["1973"]},{"key":"dc:publisher","label":"Institution","values":["Creighton University"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en_US"]},{"key":"dc:rights","label":"Dc Rights","values":["A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10504/118415"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Over fifty years elapsed between the discovery that a crude antral extract could increase the acid content of the stomach and the characterization of the specific secretory hormone, gastrin. | Gastrin was discovered to have a spectrum of actions upon the gastrointestinal tract. Vizi et al. produced direct evidence that gastrin caused the release of acetylcholine from Auerbach's plexus of guinea pig terminal ileum which, in turn, caused the muscle to contract. The purpose of this study was to verify the findings of Vizi et al. and to describe the mechanism and sites at which this action of gastrin was mediated."]},{"key":"dc:title","label":"Title","values":["The Mechanism of the Action of Gastrin on Guinea Pig Ileum Smooth Muscle"]}]}],"canonical_facts":{"dc:contributor.advisor":["Magee, Donal F."],"dc:creator":["Morelock, Michael Dennis"],"dc:date.accessioned":["2018-06-18T15:55:50Z"],"dc:date.available":["2018-06-18T15:55:50Z"],"dc:date.issued":["1973"],"dc:description.abstract":["Over fifty years elapsed between the discovery that a crude antral extract could increase the acid content of the stomach and the characterization of the specific secretory hormone, gastrin. | Gastrin was discovered to have a spectrum of actions upon the gastrointestinal tract. Vizi et al. produced direct evidence that gastrin caused the release of acetylcholine from Auerbach's plexus of guinea pig terminal ileum which, in turn, caused the muscle to contract. The purpose of this study was to verify the findings of Vizi et al. and to describe the mechanism and sites at which this action of gastrin was mediated."],"dc:identifier.uri":["http://hdl.handle.net/10504/118415"],"dc:language.iso":["en_US"],"dc:publisher":["Creighton University"],"dc:rights":["A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."],"dc:title":["The Mechanism of the Action of Gastrin on Guinea Pig Ileum Smooth Muscle"],"dc:type":["Thesis"]},"updated_at":"2026-07-24T01:50:57Z"}