The Metabolism of Normal and Malignant Tissue Culture Cell Strains

Warburg in his classic monograph postulated that the physiological cause of malignancy is an Interference with cell respiration. He stated that when there Is an Injury to cellular respiration the cell usually dies, but If the cell survives a tumor results. In 1956 he reaffirmed this hypothesis by stating that tumorogenesis involves two principal steps which are: an irreversible damage to the respiratory mechanism of the cell which in turn is accompanied or followed by a marked Increase in both the aerobic and the anaerobic glycolytic mechanism.

Grantor dc:publisher

Creighton University

Year dc:date.issued

1959

Author dc:creator

• Andrews, Richard V.

Advisor dc:contributor.advisor

• Phillips, Hugh J.

Statement dc:rights

• A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above.

Language dc:language.iso

en_US

Handle dc:identifier.uri

http://hdl.handle.net/10504/117925

OAI identifier oai:identifier

oai:cdr.creighton.edu:10504/117925