{"id":{"repo_id":"creighton","oai_identifier":"oai:cdr.creighton.edu:10504/116917"},"canonical_url":"https://search.dev.ndltd.org/etd/creighton/oai:cdr.creighton.edu:10504/116917","repository":{"repo_id":"creighton","name":"Creighton University","base_url":"https://cdr.creighton.edu/server/oai/request"},"display":{"title":"The Gradient Method of Sensitivity and a Study of Stability of Antibiotics in Agar","abstract":"The fundamentals of antibiotic therapy and laboratory investigations have been fully explored for more than a decade since penicillin was made available for general use. Investigators delved into their mode of action and factors influencing their activity and the correlation between in vitro sensitivity and clinical results. The properties, potentialities and limitations of antibiotics discovered in this brief span of time, guided the practitioner to correct and discriminate use. | However, the search is still continuing for an ideal omnipotent drug, with no limitation as to its use. | The preparation of this paper was undertaken in an attempt to present a review of sensitivity testing of antibiotics in vitro and their stability in agar media, A mere fraction of the knowledge of in vitro activity is presented here.","abstract_html":"The fundamentals of antibiotic therapy and laboratory investigations have been fully explored for more than a decade since penicillin was made available for general use. Investigators delved into their mode of action and factors influencing their activity and the correlation between in vitro sensitivity and clinical results. The properties, potentialities and limitations of antibiotics discovered in this brief span of time, guided the practitioner to correct and discriminate use. | However, the search is still continuing for an ideal omnipotent drug, with no limitation as to its use. | The preparation of this paper was undertaken in an attempt to present a review of sensitivity testing of antibiotics in vitro and their stability in agar media, A mere fraction of the knowledge of in vitro activity is presented here.","abstract_has_math":false,"creators":["Siekaniec, Carmelita Ann"],"institution":"Creighton University","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Severens, James M."],"committee_chairs":[],"committee_members":[],"year":1958,"date_issued":"1958","date_published":"1958","updated_at":"2026-07-24T01:49:51Z","subjects":["Microbiology"],"languages":["en_US"],"rights":["A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/10504/116917","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Severens, James M."]},{"key":"dc:creator","label":"Author","values":["Siekaniec, Carmelita Ann"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2018-02-19T22:07:42Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2018-02-19T22:07:42Z"]},{"key":"dc:date.issued","label":"Date","values":["1958"]},{"key":"dc:publisher","label":"Institution","values":["Creighton University"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Microbiology"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en_US"]},{"key":"dc:rights","label":"Dc Rights","values":["A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/10504/116917"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The fundamentals of antibiotic therapy and laboratory investigations have been fully explored for more than a decade since penicillin was made available for general use. Investigators delved into their mode of action and factors influencing their activity and the correlation between in vitro sensitivity and clinical results. The properties, potentialities and limitations of antibiotics discovered in this brief span of time, guided the practitioner to correct and discriminate use. | However, the search is still continuing for an ideal omnipotent drug, with no limitation as to its use. | The preparation of this paper was undertaken in an attempt to present a review of sensitivity testing of antibiotics in vitro and their stability in agar media, A mere fraction of the knowledge of in vitro activity is presented here."]},{"key":"dc:title","label":"Title","values":["The Gradient Method of Sensitivity and a Study of Stability of Antibiotics in Agar"]}]}],"canonical_facts":{"dc:contributor.advisor":["Severens, James M."],"dc:creator":["Siekaniec, Carmelita Ann"],"dc:date.accessioned":["2018-02-19T22:07:42Z"],"dc:date.available":["2018-02-19T22:07:42Z"],"dc:date.issued":["1958"],"dc:description.abstract":["The fundamentals of antibiotic therapy and laboratory investigations have been fully explored for more than a decade since penicillin was made available for general use. Investigators delved into their mode of action and factors influencing their activity and the correlation between in vitro sensitivity and clinical results. The properties, potentialities and limitations of antibiotics discovered in this brief span of time, guided the practitioner to correct and discriminate use. | However, the search is still continuing for an ideal omnipotent drug, with no limitation as to its use. | The preparation of this paper was undertaken in an attempt to present a review of sensitivity testing of antibiotics in vitro and their stability in agar media, A mere fraction of the knowledge of in vitro activity is presented here."],"dc:identifier.uri":["http://hdl.handle.net/10504/116917"],"dc:language.iso":["en_US"],"dc:publisher":["Creighton University"],"dc:rights":["A non-exclusive distribution right is granted to Creighton University and to ProQuest following the publishing model selected above."],"dc:subject":["Microbiology"],"dc:title":["The Gradient Method of Sensitivity and a Study of Stability of Antibiotics in Agar"],"dc:type":["Thesis"]},"updated_at":"2026-07-24T01:49:51Z"}